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Sergey V. Bukharov Yulia N. Oludina Roza G. Tagasheva Viktor V. Syakaev Rashid Z. Musin 《Phosphorus, sulfur, and silicon and the related elements》2016,191(7):1069-1074
The synthesis of N-[dimethoxyphosphoryl-(3,5-di-tert-butyl-4-hydroxyphenyl)] methylisatins has been performed by the addition of isatin and 5-butylisatin to the double bond of dimethyl-(3,5-di-tert-butyl-4-oxo-2,5-cyclohexadienylidene)methylphosphonate. Subsequent functionalization of the compounds synthesized with thiosemicarbazide hydrochloride, 3-(3′,5′-di-tert-butyl-4′-hydroxyphenyl)propionic acid hydrazide, and isonicotinic acid. Hydrazide gave isatin derivatives containing several pharmacophore fragments. Each of them has the ability to the increase the antioxidant and biological activities of these compounds. 相似文献
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Yu. N. Oludina S. V. Bukharov A. R. Burilov R. G. Tagasheva V. V. Syakaev R. Z. Musin E. F. Akhmetova G. N. Nugumanova 《Russian Chemical Bulletin》2014,63(1):115-117
Addition of isatin to the exocyclic double bond of dimethyl (3,5-di-tert-butyl-4-oxocyclohexa-2,5-dienylidene)methylphosphonate gave dimethyl (3,5-di-tert-butyl-4-hydroxyphenyl)(2,3-dioxo-2,3-dihydro-1H-indol-1-yl)methylphosphonate. Its subsequent functionalization in reactions with thiosemicarbazide and 3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionohydrazide yielded isatin derivatives containing several pharmacophoric fragments. 相似文献
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R. G. Tagasheva S. V. Bukharov G. N. Nugumanova Yu. N. Oludina M. A. Sazykina I. S. Sazykin E. Yu. Seliverstov M. I. Khammami 《Russian Journal of General Chemistry》2016,86(3):602-606
Salicylaldehyde derivatives containing sterically hindered phenol fragments were synthesized. The compounds obtained are capable to offer protection against UV radiation. 相似文献
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Oludina Yu. N. Ibatullina E. D. Bukharov S. V. Nugumanova G. N. Tagasheva R. G. Deberdeev R. Ya. 《Russian Journal of General Chemistry》2015,85(2):383-386
Russian Journal of General Chemistry - Alkyl splitting of 4-acetylamino-N-(3,5-di-tert-butyl-4-hydroxybenzyl)benzenesulfonamide with alkali solution has been discovered, the reaction being uncommon... 相似文献
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S. V. Bukharov Yu. N. Oludina R. A. Khabibullina A. R. Burilov E. L. Gavrilova 《Phosphorus, sulfur, and silicon and the related elements》2013,188(12):822-830
AbstractThe insertion of fragments of sterically hindered phenols into the structure of phosphorylacetic acids hydrazides in their reactions with 3,5-di-tert-butyl-4-hydroxybenzylacetates and sterically hindered 2- and 4-hydroxybenzaldehydes has been carried out. The synthesis of 3,5-di-tert-butyl-4-benzyl derivatives of 5-[(diphenylphosphoryl) methyl]-2,4-dihydro-3H-1,2,4-triazol-3-thiones was also carried out. 相似文献
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