The interaction of coordinationally unsaturated 2,9-dimethylphenanthroline cobalt complex with adenine nucleotides

The study of complex formation between adenosine triphosphate (ATP) or adenosine diphosphate (ADP) and coordinationally unsaturated cobalt complex with 2, 9-dimethyl-o-phenanthroline (L) showed the possibility of formation of relatively stable mixed ligand complex CoL·ATP (log=4.45). The latter may be formed under the oxidative phosphorylation conditions in mitochondria. The presence of ATP in the complex provides the specific inhibition of the ATPase active center.Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 4, pp. 744–748, April, 1994.     

A study of the reactions of the chemical modification of chymotrypsin. I

Summary The reaction of chymotrypsin with a number of modified analogs of the specific inhibitor of chymotrypsin L-1-tosylamido-2-phenylethyl chloromethyl ketone has been studied; the compounds investigated were D-1-tosylamido-2-phenethyl chloromethyl ketone, phenethyl chloromethyl ketone (PECK), and benzylethyl chloromethyl ketone (BCMK).It has been shown that D-TAPK does not possess inhibiting activity. The inhibiting capacity of PECK is considerably reduced. A simultaneous decrease in the length of the carbon chain and the elimination of the tosylamino group (BCMK) practically destroys the inhibiting action of the reagent.Khimiya Prirodnykh Soedinenii, Vol. 4, No. 2, pp. 116–120, 1968     

Cobalt complexes-hydrophobic derivatives of vitamin B12 in catalysis and electrocatalysis

Conclusions The state of the reaction of the catalyst with the electron donor is important for both homogeneous catalytic oxidation of quinols by cobalt corrin complexes and for electrolytic reduction of oxygen on electrodes modified by these complexes; the efficiency of this reaction is determined by the correspondence of the hydrophobic properties of the catalyst and substrate.Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 4, pp. 759–765, April, 1988.We would like to thank I. P. Rudakova for her valuable advice on synthesis of the cobryrinic acid derivatives.     

Transition-metal complexes as catalysts of active oxygen species formation in autooxidation reactions

Water-soluble Co and Fe phthalocyanines catalyze autooxidation of ascorbic acid and hydroquinone. Co and Fe phthalocyanines with cationic substituents in macroligands and also sulfo- and carboxy-substituted phthalocyanines were found to be the most active. Using the specific radical traps, the formation of active oxygen species (O₂ ^–., OH^–) in the course of the dark reaction of autooxidation was established.Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 8, pp. 2105–2111, August, 1996.     

Catalytic autooxidation of hydroquinone in the presence of chelate complexes of transition metals

Autooxidation of hydroquinone was studied in the presence of Co and Cu complexes with salene, decamethyl-octadehydrocorrine, corrine and o-phenanthroline as ligands in aqueous solution and in protic and aprotic solvents. A possible mechanism of the catalytic action of some active complexes is discussed.

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, Co, Cu , , - . .

     

Generation of OH radicals in redox reactions of cobalt corrin complexes

Corrin complexes of cobalt reduce molecular oxygen to H₂O₂ in the presence of a reducing agent (ascorbic acid or ubiquinol Q₉H₂). The complex of divalent cobalt [Co^II(cor)]_OMe ⁺ClO₄ ^– breaks down H₂O₂ according to a radical mechanism, with the formation of OH radicals.Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 12, pp. 2679–2683, December, 1989.