Evaluation of thyroid scintigraphy in small animals

Thyroid scintigraphy in rats and mice with 99mTc and 123I was attempted to examine whether this modality might be used in small animals and to describe the possibilities of its application in examining experimentally produced thyroid diseases. A human gamma camera with a pinhole collimator improved for small animals was used for imaging. Thyroid images with 99mTc were obtained 20 minutes after injection and those with 123I were 24 hours after administration. All the scintigrams, although those obtained from mice with 99mTc displayed overlapped salivary gland images, demonstrated sufficiently clear images in size and shape, which showed that thyroid scintigraphy in small animals should be applicable in examining experimentally produced thyroid diseases.     

SPECTRAL ANALYSIS OF CHLOROPHYLL a AGGREGATES IN THE PRESENCE OF WATER-SOLUBLE MACROMOLECULES

Abstract— The absorption and fluorescence spectra of chlorophyll a (Chi a) aggregates formed in aqueous solutions of polyvinyl alcohol) (PVA), polyvinyl pyrrolidone) (PVP), and bovine serum albumin (BSA) were analyzed by curve-fitting methods in the wavelength region from 650 to 800 nm. The results indicated that the aggregation of Chi a to polymeric forms such as (Chia–2H₂0), was suppressed in the presence of the macromolecules. The suppression was due to a coordination of macromolecule bound ligands to Chi a and was strongest in BSA and weaker in PVA. There were differences in the spectra even though the same types of polymeric Chi a forms were observed due to characteristically different composition of these forms. Fluorescence patterns indicated that energy was transferred from the shorter to the longer wavelength forms.     

Construction of an asymmetric quaternary carbon via an asymmetric aza-Claisen rearrangement and its application in the total synthesis of (+)-α-cuparenone

Excess lithium hexamethyldisilazide (LHMDS) with LiCl prompted the asymmetric aza-Claisen rearrangement of carboxamide and retarded the decomposition of its amide enolate. The addition of these two reagents was a key step that led to the total synthesis of (+)-α-cuparenone with a stereogenic quaternary center.     

Poincarésupergravity as broken superconformal gravity

We present a locally superconformal invariant theory of supergravity which is gauge equivalent to the usual, Poincaré, supergravity. This is achieved by means of a compensating scalar supermultiplet. This shows that local superconformal symmetry can be made compatible with gravitational phenomenology.     

Observation of vacuum-ultraviolet Ar2* radiation gain at 126 nm produced by an ultrashort high-intensity laser pulse propagating in a hollow fiber

We observed a small-signal gain of Ar2* emission at 126 nm by use of a hollow fiber to guide the high-intensity laser propagation in high-pressure Ar. The small-signal gain coefficient was measured to be 0.05 cm(-1) at 126 nm. Kinetic analysis revealed that the electrons produced by the high-intensity laser through an optical-field-induced ionization process initiated the Ar2* production processes. The increase in the emission intensity was measured to be exp(2.5), with an increase in the fiber length.     

Sterol composition of a cultured marine dinoflagellate,Heterocapsa circularisquama

The composition of sterols was determined in a cultured marine dinoflagellate Heterocapsa circularisquama. Ten kinds of the sterol in H. circularisquama were identified by capillary gas chromatography-mass spectrometry. The major sterol was a 4-methyl sterol, 4alpha,23,24-trimethyl-5alpha-cholest-22E-en-3beta-ol (dinosterol) which is the common sterol in many dinoflagellates.     

Optimization of hollow fiber pulse compression using pressure gradients

We present a study on the optimization of multi-mJ spectral broadening in neon-filled hollow fibers using pressure gradients. It is found that the intensity of the laser pulse at the entrance of the hollow fiber should be below or at the level where multi-photon ionization (MPI) starts to occur. If the intensity is higher than the threshold value for MPI, ionization can significantly reduce the throughput efficiency. The extension of the scheme to a terawatt power level is also addressed. PACS 42.65.Re; 42.65.Jx; 42.65.k     

The scheduling of deliveries in a production-distribution system with multiple buyers

In a real production and distribution business environment with one supplier and multiple heterogeneous buyers, the differences in buyers’ ordering cycles have influence on production arrangements. Consequently, the average inventory level (AIL) at the supplier’s end is affected by both the production policy and the ordering policy, typically by the scheduling of deliveries. Consequently, the average inventory holding cost is most deeply affected. In this paper, it is proposed that the scheduling of deliveries be formulated as a decision problem to determine the time point at which deliveries are made to buyers in order to minimize the supplier’s average inventory. A formulation of the average inventory level (AIL) in a production cycle at the supplier’s end using a lot-for-lot policy is developed. Under the lot-for-lot policy, the scheduling of deliveries (SP) is formulated as a nonlinear programming model used to determine the first delivery point for each buyer with an objective to minimize the sum of the product of the individual demand quantity and the first delivery time for each buyer. Thus, the SP model determines not only the sequence of the first deliveries to individual buyers, but also the time when the deliveries are made. An iterative heuristic procedure (IHP) is developed to solve the SP model assuming a given sequence of buyers. Six sequence rules are considered and evaluated via simulation.