The Effect of the Nature and Structure of Adsorbents on Interaction with Ibuprofen

The interaction of ibuprofen [2-(4-isobutylphenyl)propionic acid] with the surface of carbon and oxide adsorbents was investigated. The significant role of wide pores during the adsorption of ibuprofen on carbon adsorbents in the presence of protein molecules was demonstrated. At low concentrations ibuprofen is adsorbed on the surface of hydrophilic and hydrophobic adsorbents in the form of a monomer, but the contribution from the adsorbed dimer increases with increase in its concentration.     

Investigation of the intramembrane distribution of chlorin e6 derivatives by using fluorescence quenching

Belarusian State University, 4, F. Skorina Ave., Minsk, 220050, Belarus. Translated from Zhurnal Prikladnoi Spektroskopii, Vol. 62, No. 2, pp. 179–187, March–April, 1995     

Effect of temperature and a weakly polar organic medium on water localization in slit-like pores of various sizes in microporous activated carbon

The joint adsorption of water and methane in pores of the synthetic carbon adsorbent with specific surface area of 3463 m²/g was studied by ¹H NMR spectroscopy. It was shown that during adsorption of water and methane in pores of activated carbon AC86 under conditions of low surface filling the adsorbate molecules are localized not only in micropores, but in mesopores as well, and are revealed in the spectra as several signals with different values of the chemical shift. A substantial drop in the magnetic shielding effect of the carbon surface was detected upon a reduction in temperature; this is explained by the presence of two energy minima on the curves of the adsorption potential energy (close to the walls and in the center of pores) and allows the migration of adsorbed molecules from the walls to the center of pores, which are characterized by a lower shielding effect.     

Catalytic decomposition of peroxides by medicinal activated carbons

The catalytic properties of carbon hemosorbents were investigated in reactions of the decomposition of peroxide compounds simulating the peroxides of lipids. It was shown that SKN carbons have much higher catalytic activity than SKS or VAS-MU. A mechanism of the catalytic action of the carbons during hemocarboperfusion is proposed on the basis of theories of radical-chain degenerate branched processes. It is concluded that catalytic reactions must be taken into account in extracorporal detoxification. The mechanism that is given is in agreement with the experimental data according to the intensity of the EPR signal in the blood during ischemic heart disease and other pathologies.Translated from Teoreticheskaya i Éksperimental'naya Khimiya, Vol. 25, No. 3, pp. 366–370, May–June, 1989.