A mixed‐ligand quinazoline‐based Ni(II) Schiff base complex: Synthesis,characterization, crystal structure,antimicrobial investigation and catalytic activity for the synthesis of 2H–indazolo[2,1‐b]phthalazine‐triones

A tridentate Schiff base ligand, (E)‐3‐((2‐hydroxy‐3‐methoxybenzylidene)amino)‐2‐methylquinazolin‐4(3H)‐one [HL], and its mixed‐ligand Ni(II) complex [Ni(L)(imi)], were synthesized and fully characterized using elemental analysis, FT‐IR, UV–Vis and ¹HNMR spectroscopy techniques. The structure of the synthesized ligand and complex was determined with single crystal X‐ray diffraction method. In the complex, a square planner geometry was observed around the Ni(II) central atom coordinated with the donor atoms of the Schiff base ligand and one nitrogen of imidazole group. In addition, the catalytic activity of the complex on the three‐component condensation of hydrazine hydrate with phthalic anhydride and dimedone to obtain 2H–indazolo[2,1‐b]phthalazine‐triones was investigated. Furthermore, in‐vitro antimicrobial studies were performed that indicated the great antibacterial activities of the Ni(II) complex against Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa and Bacillus cereus bacteria.     

Preparation,crystal structure,spectroscopic studies,DFT calculations,antibacterial activities and molecular docking of a tridentate Schiff base ligand and its cis‐MoO2 complex

We synthesized a tridentate Schiff base ligand, 6‐(((2‐hydroxyphenyl)amino)methylene)‐2‐methoxycyclohexa‐2,4‐dienone [H₂L], as well as its Mo(VI) complex [MoO₂(L)(DMSO)], and then characterized them completely using elemental analysis, FT‐IR, UV–Vis and ¹HNMR spectroscopy techniques. X‐ray single crystal diffraction method was used for the determination of the structure of the synthesized ligand and complex. All other spectroscopic techniques performed, confirmed that [MoO₂(L)(DMSO)]had an octahedral geometry around the Mo(VI) central ion coordinated by the donor atoms of the deprotonated ligand, two oxido groups and one oxygen atom of DMSO molecule. Hybrid functional B3LYP with DGDZVP as basis set was applied for DFT calculations of the compounds in their ground state. The MEP, Mulliken, HOMO‐LUMO energy gap and thermodynamic properties of the compounds were also theoretically predicted. In‐vitro antimicrobial studies on the synthesized compounds indicated the great antibacterial activities of the Mo(VI) complex against Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa and Bacillus cereus bacteria.     

Effect of synthesis parameters on the crystallinity of EU-1 zeolite for the m-xylene isomerization reaction

Russian Journal of Applied Chemistry - The EU-1 zeolite with Si/Al = 25 was synthesized by hexamethonium bromide as a template. The effects of crystallization time, synthesis temperature, and the...     

Comparison of catalytic performance of synthesized EU-1 zeolite with dealuminated EU-1 zeolite for <Emphasis Type="Italic">m</Emphasis>-xylene isomerization reaction

EU-1 zeolite was synthesized with high purity by a hydrothermal method and under optimum conditions: synthesis time 72 h, temperature 200°C, and aging time 12 h. Then, the synthesized EU-1 zeolite was modified by dealumination with nitric acid and the changes of the properties such as surface area, pore volume, and Si/Al ratio were investigated. The catalytic performance of these two catalysts was studied and compared with a commercial mordenite catalyst for meta-xylene isomerization reaction in a fixed bed reactor. The results showed that the modification of catalyst with acid increases Si/Al ratio from 25 to 50 due to the removal of a number of aluminium atoms from the framework of zeolite. Also the catalyst surface area increased from 300.237 m² g^?1 for EU-1 to 333.639 m² g^?1 for modified EU-1. According to results, the modified Eu-1 had higher para/ortho ratio, meta-xylene conversion, and para-xylene yield than EU-1 and commercial mordenite in the meta-xylene isomerization reaction.