The biopolymer chitosan was chemically modified by grafting polyacrylamide or polyacrylic acid in a homogeneous aqueous phase using potassium persulfate (KPS) as redox initiator system in the presence of N,N-methylene-bis-acrylamide as a crosslinking agent. The influence of the grafted chitosan on calcium salts crystallization in vitro was studied using the sitting-drop method. By using polyacrylamide grafted chitosan as substrate, rosette-like CaSO4 crystals were observed. This was originated by the presence of sulfate coming from the initiator KPS. By comparing crystallization on pure chitosan and on grafted chitosan, a dramatic influence of the grafted polymer on the crystalline habit of both salts was observed. Substrates prepared by combining sulfate with chitosan or sulfate with polyacrylamide did not produce similar CaSO4 morphologies. Moreover, small spheres or donut-shaped CaCO3 crystals on polyacrylic acid grafted chitosan were generated. The particular morphology of CaCO3 crystals depends also on other synthetic parameters such as the molecular weight of the chitosan sample and the KPS concentration. 相似文献
Because of the growing importance of pH‐sensitive hydrogels as drug delivery systems, biocompatible copolymeric hydrogels based N‐vinyl‐2‐pyrrolidinone (NVP) and methacrylic acid (MAA) were designed and synthesized. These hydrogels were investigated for oral drug delivery. Radical copolymerizations of N‐vinyl‐2‐pyrrolidinone (NVP) and methacrylic acid (MAA) with the various ratios of cross‐linking agent were carried out at 70 °C. Azabisisobutyronitrile (AIBN) was the free‐radical initiator employed and Cubane‐1,4‐dicarboxylic acid (CDA) linked to two 2‐hydroxyethyl methacrylate (HEMA) group was the crosslinking agent (CA) used for hydrogel preparations. The hydrogels were characterized by differential scanning calorimetry and FT‐IR. Equilibrium swelling studies were carried out in enzyme‐free simulated gastric and intestinal fluids (SGF and SIF, respectively). A model drug, olsalazine [3,3′‐azobis (6‐hydroxy benzoic acid)] (OSZ) as an azo derivative of 5‐aminosalicylic acid (5‐ASA), was entrapped in these gels and the in‐vitro release profiles were established separately in both enzyme‐free SGF and SIF. The drug‐release profiles indicated that the amount of drug released depended on the degree of swelling. The swelling was modulated by the amount of crosslinking of the polymer bonded drug (PBDs) prepared. Based on the great difference in hydrolysis rates at pH 1 and 7.4, these pH‐sensitive hydrogels appear to be good candidates for colon‐specific drug delivery. 相似文献
Journal of Thermal Analysis and Calorimetry - Artificial neural network/kriging interpolation method optimization method which is evaluated concerned the hybrid nanofluid composed of iron oxide... 相似文献
Processing the aerosol of metal salts in non-equilibrium plasma represents a promising technique that combines the advantages
of spray pyrolysis with the high reactivity of plasmas at nearlaboratory temperature in order to produce mixed-oxides and
perovskite materials. The aim of this paper is to describe the principles of this new technique and to present the various
applications and latest developments. This technique’s capacity to deposit various mixed metal oxides with precise stoichiometry
is demonstrated. It is shown that oxidant plasma species play a key role in the chemical transformation of starting materials
into oxides at laboratory temperature, while the configuration of the reactor determines the morphology and texture of the
deposited layers. Two different reactor configurations are presented. The porous layers of LaxSr1−xMnO3 as the cathode for fuel cells were synthesised in a wave shock reactor configuration, while nanostructured ZnO-Al layers
to form a transparent conductive cathode for photovoltaic cells were deposited in the spray plasma reactor of the latest generation
for this technique. The experimental results emphasise the role of plasma species in the rate of chemical reactions and in
the chemical composition of the deposited layers. 相似文献
We investigated theoretically the effects of the cross‐stream migration and the local average orientation of rodlike particles on the shape‐based separation using field‐flow fractionation. The separation behavior was analyzed by comparing the retention ratios of spheres and rods. The retention ratio of a rod was evaluated through the derivation of its cross‐sectional concentration profile by considering the rod migration and the local average orientation. Our study in various flow conditions showed that the rod migration, caused by the hydrodynamic interaction with a wall, can affect the separation behavior as a lift‐hyperlayer mode. We also demonstrated that the local average orientation, which is a function of a local shear rate and a rotational diffusivity, results in the transverse diffusivity that is different from its perpendicular diffusivity. These results suggest that the experimental separation behaviors of rods in field‐flow fractionation may not be fully explained by the current theory based on the normal mode and the steric mode. We also characterized each condition where one of the normal mode, the steric mode of spheres, and the lift‐hyperlayer mode of rods is dominant. 相似文献
Safety issues of Li-ion batteries imposed by unfavorable thermal behavior accentuate the need for efficient thermal management systems to prevent the runaway conditions. To that end, a hybrid thermal management system is designed and further investigated numerically and experimentally in the present study. The passive cooling system is fabricated by saturating copper foam with paraffin as the phase change material (PCM) and integrated with an active cooling system with alumina nanofluid as the coolant fluid. Results for various Reynolds numbers and different heating powers indicate that the hybrid nanofluid cooling system can successfully fulfill safe operation of the battery during stressful operating conditions. The maximum time in which all PCM field is changed to the liquid phase is defined as the onset of the stressful conditions. Therefore, the start time of stressful conditions at 41 W and Re 420 is increased from 3700 s with nanofluid composed of 1% volume fraction nanoparticles (VF-1%) to 4600 s with nanofluid VF-2% during high current discharge rates. Nanofluid cooling extends the operating time of the battery in comparison with the water-based cooling system with 200-s (nanofluid with volume fraction of 1%) and 900-s (nanofluid with volume fraction of 2%) increases in operating time at Reynolds of 420. Using nanofluid, instead of water, postpones the onset of paraffin phase transition effectively and prolongs its melting time which consequently leads to a decrease in the rate of temperature rise.
Crystallography Reports - For structures with a C2PO2 skeleton, a comparison of “single-and-half” phosphorus–oxygen bonds with single and double phosphorus–oxygen bonds is... 相似文献
A blend/clay nanocomposites of 50/50 (wt%) NR/SBR was prepared via mixing the latex of a 50/50 NR/SBR blend with an aqueous clay dispersion and co‐coagulating the mixture. The structure of the nanocomposite was characterized by transmission electron microscopy (TEM) and X-ray diffraction (XRD). Nanocomposites containing less than 10 phr clay showed a fully exfoliated structure. After increasing the clay content to 10 phr, both nonexfoliated (stacked layers) and exfoliated structures were observed in the nanocomposites. The results of mechanical tests showed that the nanocomposites presented better mechanical properties than clay‐free NR/SBR blend vulcanizate. Furthermore, tensile strength, tensile strain at break, and hardness (shore A) increased with increasing clay content, up to 6 phr, and then remained almost constant. 相似文献
The flow of non-Newtonian fluids through two-dimensional porous media is analyzed at the pore scale using the smoothed particle
hydrodynamics (SPH) method. A fully explicit projection method is used to simulate incompressible flow. This study focuses
on a shear-thinning power-law model (n < 1), though the method is sufficiently general to include other stress-shear rate relationships. The capabilities of the
proposed method are demonstrated by analyzing a Poiseuille problem at low Reynolds numbers. Two test cases are also solved
to evaluate validity of Darcy’s law for power-law fluids and to investigate the effect of anisotropy at the pore scale. Results
show that the proposed algorithm can accurately simulate non-Newtonian fluid flows in porous media. 相似文献