4,4-Dialkoxybutan-2-ones as Synthons

The review considers the synthetic potential of 4,4-alkoxybutan-2-ones which are promising synthons available from diacetylene-containing industrial gases. The reactivity of 4,4-dialkoxybutan-2-ones toward mono- and difunctional reagents, as well as in cycloaddition processes, is discussed.__________Translated from Zhurnal Organicheskoi Khimii, Vol. 41, No. 1, 2005, pp. 9–32.Original Russian Text Copyright © 2005 by Maretina.     

Synthesis of 2-substituted isoxazoline and imidazoline,containing a vinylacetyl fragment

The reaction of4-dialkylamino-1-acetyl-1-buten-3-ynes with 1-hydroxy-2-aminoethane and 1,2-diaminoethane was used to synthesize 2-substituted oxazoline and imidazoline, containing a fully enolized vinylacetyl fragment.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 10, pp. 1409–1410, October 1992.     

Porphyrin-ethynyl arrays: Synthesis, design, and application

The review discusses various models of multiporphyrin arrays with ethyne, diyne, and E- and Z-enediyne linkers. The concept implying multivalence of such systems is considered. Porphyrin-ethynyl arrays are nanosize structures that are promising from the viewpoint of their application in up-to-date fields of medicine and technics, including design of biocomputers.     

Specific Features of Alkenynamines Chemistry

The reactivity of alkenynamines is considered. Main publications are reviewed concerning reactions of these unsaturated amines with unicentric and multicentric reagents, their participation in cycloadditions affording new classes of polyfunctional compounds and furnishing new approach to building up heterocyclic systems. This research treats a kind of fine organic synthesis promising for industrial applications.     

Amino-α,β-unsaturated ethylenic and acetylenic carbonyl compounds as synthons for the assembly of heterocycles (review)

The reactivity of en- and ynaminocarbonyl compounds towards two-center reactants to give five- and sevenmembered heterocycles with two heteroatoms, and condensed rings, is reviewed. The behavior of these systems towards 1,3-dipolar cycloaddition is noted.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 7, pp. 867–878, July, 1992.     

Design strategy of enediynes and enyne-allenes

The review summarizes synthetic approaches to enediynes and enyne-allenes that are responsible for a Bergman and Myers-Saito cycloaromatizations resulting in the formation of benzene, β-substituted naphthalene, and acene derivatives. Cycloaromatization paths leading to fulvene and indene systems in the presence of radical and ionic initiators, as well as of metal catalysts, are discussed. Practical importance of the syntheses is noted.     

Effect of ferrocene on the synthesis of graft copolymers of vinylpolysiloxane and styrene

Russian Journal of General Chemistry - The effect of ferrocene on the synthesis of graft poly(dimethylsiloxanes) by radical copolymerization of a polysiloxane containing terminal trivinylsiloxy...     

Synthesis of dienic N,S-ketene acetals of the pyrimidine series

The reaction of alkenynylamines with thiols of the pyrimidine series proceeds regiospecifically at the acetylene bond with he formation of N,S-ketene acetals of the pyrimidine series.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 11, pp. 1539–1540, November, 1990.     

Reaction of alkenynylamines with 2-aminoresorcinol as a method for the synthesis of 2-(2-alkenyl)-4-hydroxybenzoxazoles

The reaction of 1-diethylamino-(4-methyl)-3-penten-1-ynes with 2-aminoresorcinol leads to the formation of 2-(2-alkenyl)-4-hydroxybenzoxazoles.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 2, pp. 231–232, February, 1992.     

Cyclization of substituted 1,3-alkenynes with thiourea

2-Mercapto-4-methylpyrimidine was obtained by the reaction of 1,3-butenyne ethers, thioethers, and amines with thiourea. The corresponding 2-mercapto-4-alkylpyrimidines were obtained for the first time by analogous cyclization of 1-methoxy-1-buten-3-yne homologs (CH₃OCH=CHC=CR, where R=CH₃, C₂H₅, and C₃H₇) with thiourea. The effect of the nature of the substituents in the 1,3-enyne system on the capacity for cyclization with thiourea was investigated.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 6, pp. 843–845, June, 1971.