排序方式: 共有36条查询结果,搜索用时 31 毫秒
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Background
Growth hormone (GH) plays an incompletely understood role in the development of the central nervous system (CNS). In this study, we use transgenic mice expressing a growth hormone antagonist (GHA) to explore the role of GH in regulating postnatal brain, spinal cord and body growth into adulthood. The GHA transgene encodes a protein that inhibits the binding of GH to its receptor, specifically antagonizing the trophic effects of endogenous GH. 相似文献4.
P. H. Willcocks N. R. Bosley A. Broadhurst I. D. Luscombe 《Journal of Thermal Analysis and Calorimetry》1999,56(3):1413-1418
The use of thermal analysis as part of a quality system in industry can be effective only if the techniques are made to conform
to high standards of quality assurance. Achieving these high standards is not problem free and there remain many issues which
require the attention of thermal analysts in industry and academe. Fundamental aspects which have been considered include
limitations due to instrument design, problems in computerised control and analysis. A key aim is towards validation of data
at international level.
This revised version was published online in August 2006 with corrections to the Cover Date. 相似文献
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Speech processing studies using an acoustic model of a multiple-channel cochlear implant 总被引:1,自引:0,他引:1
P J Blamey R C Dowell Y C Tong A M Brown S M Luscombe G M Clark 《The Journal of the Acoustical Society of America》1984,76(1):104-110
The speech perception of two multiple-channel cochlear implant patients was compared with that of three normally hearing listeners using an acoustic model of the implant for 22 different speech tests. The tests used included a minimal auditory capabilities battery, both closed-set and open-set word and sentence tests, speech tracking and a 12-consonant confusion study using nonsense syllables. The acoustic model represented electrical current pulses by bursts of noise and the effects of different electrodes were represented by using bandpass filters with different center frequencies. All subjects used a speech processor that coded the fundamental voicing frequency of speech as a pulse rate and the second formant frequency of speech as the electrode position in the cochlea, or the center frequency of the bandpass filter. Very good agreement was found for the two groups of subjects, indicating that the acoustic model is a useful tool for the development and evaluation of alternative cochlear implant speech processing strategies. 相似文献
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We report a calculation of the thermodynamic properties of an Ising system on a fractal lattice, the Sierpinski gasket (SG). The scale-invariant geometry of SG leads to a wider critical region compared to that in translationally invariant systems. We calculate exactly the near-neighbor correlation function and specific heat and discuss their critical behaviour. 相似文献
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Tengzhou Ma Ban Xuan Dong Jonathan W. Onorato Jens Niklas Oleg Poluektov Christine K. Luscombe Shrayesh N. Patel 《Journal of polymer science. Part A, Polymer chemistry》2021,59(22):2797-2808
Molecular doping of conjugated polymers (CPs) plays a vital role in optimizing organic electronic and energy applications. For the case of organic thermoelectrics, it is commonly believed that doping CPs with a strong dopant could result in higher conductivity (σ) and thus better power factor (PF). Herein, by investigating thermoelectric performance of a polar side-chain bearing CP, poly(3-(methoxyethoxyethoxy)thiophene) (P3MEET), vapor doped with fluorinated-derivative of tetracyanoquinodimethane FnTCNQ (n = 1, 2, 4), we show that using strong dopants can in fact have detrimental effects on the thermoelectric performance of CPs. Despite possessing higher electron affinity, doping P3MEET with F4TCNQ only results in a σ (27.0 S/cm) comparable to samples doped with other two weaker dopants F2TCNQ and F1TCNQ (26.4 and 20.1 S/cm). Interestingly, F4TCNQ-doped samples display a marked reduction in the Seebeck coefficient (α) compared to F1TCNQ- and F2TCNQ-doped samples from 42 to 13 μV/K, leading to an undesirable suppression of the PF. Structural characterizations coupled with Kang-Snyder modeling of the α–σ relation show that the reduction of α in F4TCNQ-doped P3MEET samples originates from the generation of low mobility carrier within P3MEET's amorphous domain. Our results demonstrate that factors such as dopant distribution and doping efficiency within the crystalline and amorphous domains of CPs should play a crucial role in advancing rational design for organic thermoelectrics. 相似文献
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KM Varier AM Vinodkumar NVSV Prasad PV Madhusudhana Rao DL Sastry Lagy T Baby MC Radhakrishna NG Puttaswamy JJ Das P Sugathan N Madhavan AK Sinha DO Kataria 《Pramana》1999,53(3):529-533
Large enhancements have been observed in the sub-barrier fusion cross sections for Ti+Ni systems in our previous studies.
Coupled channel calculations incorporating couplings to 2+ and 3− states failed to explain these enhancements completely. A possibilty of transfer channels contributing to the residual enhancements
had been suggested. In order to investigate the role of relevant transfer channels, measurements of one- and two-nucleon transfer
were carried out for 46,48Ti+61Ni systems. The present paper gives the results of these studies. 相似文献
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Doubina N Jenkins JL Paniagua SA Mazzio KA MacDonald GA Jen AK Armstrong NR Marder SR Luscombe CK 《Langmuir : the ACS journal of surfaces and colloids》2012,28(3):1900-1908
Poly(3-methylthiophene) (P3MT) was synthesized directly from indium tin oxide (ITO) electrodes modified with a phosphonic acid initiator, using Kumada catalyst transfer polymerization (KCTP). This work represents the first time that polymer thickness has been controlled in a surface initiated KCTP reaction, highlighting the utility of KCTP in achieving controlled polymerizations. Polymer film thicknesses were regulated by the variation of the solution monomer concentration and ranged from 30 to 265 nm. Electrochemical oxidative doping of these films was used to manipulate their near surface composition and effective work function. Doped states of the P3MT film are maintained even after the sample is removed from solution and potential control confirming the robustness of the films. Such materials with controllable thicknesses and electronic properties have the potential to be useful as interlayer materials for organic electronic applications. 相似文献
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Yilin Li Xueqiao Zhang Yongcao Zhang Richard Dong Christine K. Luscombe 《Journal of polymer science. Part A, Polymer chemistry》2019,57(3):201-215
The use of luminescent solar concentrators (LSCs) offers an alternative approach to integrating photovoltaic technologies into the built environment. The research on LSCs has bloomed in the past decade in terms of searching for novel device architectures, developing new luminescent species, and employing unique host materials. This article will provide a concise review on LSCs and focus on the polymer host materials used in LSCs. Finally, we provide a brief outlook on the future development of this research area, particularly on the polymers used as host materials and luminescent species for LSCs. © 2018 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2019 , 57, 201–215 相似文献