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排序方式: 共有235条查询结果,搜索用时 31 毫秒
1.
We report on the simultaneous generation of phase-conjugate signals by degenerate four-wave mixing (DFWM) and holographic processes using a nanosecond pulse and a CW lasers in polyvinyl alcohol (PVA) films doped with four kinds of saturable absorbing dyes. For the pulse laser, of the four kinds of dye-doped PVA films, the erythrosine B-doped PVA and uranine doped-PVA films generate PC signals only by the DFWM process, while the other dye-doped PVA films generate PC signals simultaneously by not only the DFWM process but also the holographic process. Especially, the safranin T-doped PVA film generates strong PC signals by the holographic process. In contrast, all of the dye-doped PVA films generate the two types of PC signals for the CW laser. The fading of dye molecules is found to result in the generation of the holographic component of PC signals which governs the temporal behavior of the total PC signals. 相似文献
2.
Platelet aggregation potentiators from cho-rei 总被引:4,自引:0,他引:4
W Lu I Adachi K Kano A Yasuta K Toriizuka M Ueno I Horikoshi 《Chemical & pharmaceutical bulletin》1985,33(11):5083-5087
3.
A new GaAs photodetector with high sensitivity in the whole 0.8–1.4m wavelength range has been fabricated from totally depleted GaAs doping superlattices grown by molecular beam epitaxy. Photoexcited electrons and holes are separated in real space by the space-charge field of the doping superlattice immediately after excitation, yielding a high quantum efficiency of this device. Because of the complete depletion, the doping superlattice behaves like a highly resistive material, which allows application of high electric field along the layers via selectiven
+ — andp
+ -electrodes. The sensitivity of this device at 1.3 m reaches more than 90% of the original band edge response at 0.85 m, and the external quantum efficiency amounts to 65% at 0.85 m. This excellent photoresponse at longer wavelengths arises from an extremely high electric field composed of the intrinsic space charge field and applied external field, and from the existence of pronounced tail states in the forbidden gap region of the superlattice. 相似文献
4.
K Konishi H Adachi K Kita S Takamiya R Furushima H Oya I Horikoshi 《Chemical & pharmaceutical bulletin》1989,37(9):2533-2534
The effects of tetragalloylglucose (1,2,3,6-tetra-O-galloyl-beta-D-glucose) on purified complex II (succinate-ubiquinone oxidoreductase) of the mitochondrial electron transport system of Ascaris muscle were studied. Both succinate-ubiquinone-1 (Q1) oxidoreductase, and succinate dehydrogenase measured with 3-(4,5-dimethylthiazol-2-yl)- 2,5-diphenyltetrazolium bromide (MTT) in the presence of phenazine methosulfate (PMS) were inhibited by tetragalloylglucose. The inhibitions of both reductase activities of complex II were of competitive type, and the inhibitor constant (Ki) for Ascaris complex II (148 nM) was lower than that for rat liver complex II (1.5 microM). Thus, Ascaris complex II is much more sensitive to this inhibitor than the mammalian counterpart. 相似文献
5.
A low-capacity cation-exchange HPLC method for the determination of UV-absorbing organic cations such as amino acids, histidine dipeptides, and creatinine was developed. A commercially available reversed-phase column was dynamically coated with hexadecylsulfonate, and was successfully used for the cation-exchange separation with ethylenediammonium eluting ion at pH 2.5. The coated column was enough stable for the specific use with a completely aqueous mobile phase at low and constant pH; and the day-to-day reproducibility for retention time was 0.9-1.7% of RSD (relative standard deviation). The linear relation between concentrations and detector responses (area) by using a photodiode-array UV detection at 210 nm ranged from 0.2 to 1000 microM (sample size 50 microl) for 1-methylhistidine, 3-methylhistidine, histidine, creatinine, anserine, carnosine, and homocarnosine, and from 0.5 to 2000 microM for creatine, tyrosine, and phenylalanine, with less than 5% of RSD. The UV spectrum (190-300 nm) obtained during chromatography was very indicative for each analyte. Overall recoveries were 97-104%. The developed HPLC method in conjunction with preliminary fractionation technique could be applied to the analysis of urine of patient with metabolic disorder such as phenylketonuria. 相似文献
6.
A novel method for determination of inorganic oxyanions by electrospray ionization mass spectrometry using dehydration reactions 下载免费PDF全文
Hirochika Kojima Shota Kurihara Yoshito Watanabe Koki Iwamaru Kiichi Sato Kin‐ichi Tsunoda Hiroki Hotta 《Journal of mass spectrometry : JMS》2016,51(2):123-131
Novel methods for the determination of inorganic oxyanions by electrospray (ES) ionization mass spectrometry have been developed using dehydration reactions between oxyanions and carboxylic acids at the ES interface. Twelve oxyanions (VO3?, CrO42?, MoO42?, WO42?, BO33?, SiO32?, SiO44?, AsO44?, AsO2?, SeO42?, SeO32? and NO2?), out of 16 tested, reacted with at least one of four aminopolycarboxylic acids, i.e. iminodiacetic acid (IDA), nitrilotriacetic acid (NTA), trans‐1,2‐diaminocyclohexane‐N,N,N′,N′‐tetraacetic acid and triethylenetetramine‐N,N,N′,N″,N′″,N′″‐hexaacetic acid, at the ES interface to produce the dehydration products that gave intense mass ion responses, sufficient for trace analysis. As examples, trace determinations of CrVI and silica in water samples were achieved after online ion exchange chromatography, where the dehydration product of CrO42? and NTA (m/z 290) and that of SiO44? and IDA (m/z 192) were measured. The limits of detection of the respective methods were 17 nM (0.83 ng Cr/ml) for CrVI and 0.17 μM (4.8 ng Si/mL) for SiO44?. Copyright © 2016 John Wiley & Sons, Ltd. 相似文献
7.
Koki Ikemoto Shotaro Harada Seungmin Yang Taisuke Matsuno Hiroyuki Isobe 《Angewandte Chemie (Weinheim an der Bergstrasse, Germany)》2022,134(1):e202114305
A 3-nm molecule comprising a cylindrical core and cross-shaped rims was designed and synthesized by developing a modular synthetic route. By using a cyclic precursor from previous studies as a starting material, multiple carbazole units were installed at the rims of the defective cylinder. The defective cylinder was synthetically doped with two types of nitrogen atoms, that is, pyridinic and pyrrolic nitrogen atoms, which resulted in solvatochromic shifts in fluorescence by charge-transfer interactions. The structure of the large, C552H496N24 molecule was fully disclosed by crystallographic analyses, and the unique helical arrangement of nitrogen-doped cylinders in the crystal was revealed. 相似文献
8.
V. A. Kulbachinskiĭ P. V. Gurin Yu. A. Danilov E. I. Malysheva Y. Horikoshi K. Onomitsu 《Journal of Experimental and Theoretical Physics》2007,105(1):170-173
GaAs structures with implanted Mn and, additionally, with Mg for increasing the hole concentration in the implanted Mn layer are synthesized and investigated. SQUID magnetometer measurements revealed the existence of ferromagnetism in the temperature range 4.2 K ≤ T < 400 K, which is associated with the formation of the Ga1?x Mn x As solid solution and MnAs and Ga1?y Mn y clusters in the sample as a result of rapid high-temperature annealing. At temperatures from 4.2 to approximately 200 K, the anomalous Hall effect associated with additional magnetization of the sample is observed. As the temperature increases from 4.2 K, the colossal negative magnetoresistance is transformed into a positive magnetoresistance at T ≈ 35 K. 相似文献
9.
Stereoselective catalytic synthesis of 3-trifluoromethyl indolines through the [4+1] cycloaddition of benzoxazinones and sulfur ylides in a transition-metal-free manner was developed. In the presence of a catalytic amount of sodium hydride, aza-ortho-quinone methide intermediates were formed from trifluoromethyl benzoxazinones through decarboxylation after the first nucleophilic attack of sulfur ylides, which progressed to a second nucleophilic attack of sulfur ylides, resulting in the [4+1] cycloaddition. The key for this catalytic transformation is the dual attack of sulfur ylides on substrates. This unique transition-metal-free protocol is applicable to the synthesis of non-fluorinated vinyl-, ethynyl- or methyl-substituted indolines. The synthesis of 3-trifluoromethyl indoles was also achieved described under stoichiometric conditions. 相似文献
10.
Hironao Nakayama Masako Nakahara Erina Matsugi Midori Soda Tomoka Hattori Koki Hara Ayuki Usami Chiaki Kusumoto Shigeki Higashiyama Kiyoyuki Kitaichi 《Molecules (Basel, Switzerland)》2021,26(1)
Ferulic Acid (FA) is a highly abundant phenolic phytochemical which is present in plant tissues. FA has biological effects on physiological and pathological processes due to its anti-apoptotic and anti-oxidative properties, however, the detailed mechanism(s) of function is poorly understood. We have identified FA as a molecule that inhibits apoptosis induced by hydrogen peroxide (H2O2) or actinomycin D (ActD) in rat pheochromocytoma, PC12 cell. We also found that FA reduces H2O2-induced reactive oxygen species (ROS) production in PC12 cell, thereby acting as an anti-oxidant. Then, we analyzed FA-mediated signaling responses in rat pheochromocytoma, PC12 cells using antibody arrays for phosphokinase and apoptosis related proteins. This FA signaling pathway in PC12 cells includes inactivation of pro-apoptotic proteins, SMAC/Diablo and Bad. In addition, FA attenuates the cell injury by H2O2 through the inhibition of phosphorylation of the extracellular signal-regulated kinase (ERK). Importantly, we find that FA restores expression levels of brain-derived neurotrophic factor (BDNF), a key neuroprotective effector, in H2O2-treated PC12 cells. As a possible mechanism, FA increases BDNF by regulating microRNA-10b expression following H2O2 stimulation. Taken together, FA has broad biological effects as a neuroprotective modulator to regulate the expression of phosphokinases, apoptosis-related proteins and microRNAs against oxidative stress in PC12 cells. 相似文献