排序方式: 共有29条查询结果,搜索用时 15 毫秒
1.
Alick KT Law Deepak Gupta Shawn Levy Douglas C Wallace Robert J McKeon Charles R Buck 《BMC neuroscience》2004,5(1):1
Background
The adenine nucleotide translocator 1 (Ant1) is an inner mitochondrial membrane protein involved with energy mobilization during oxidative phosphorylation. We recently showed that rodent Ant1 is upregulated by transforming growth factor-beta (TGF-β) in reactive astrocytes following CNS injury. In the present study, we describe the molecular mechanisms by which TGF-β1 regulates Ant1 gene expression in cultured primary rodent astrocytes. 相似文献2.
Smith K. D. Klasson K. T. Clausen Ackerson E. C. Gaddy J. L. 《Applied biochemistry and biotechnology》1991,28(1):787-796
Applied Biochemistry and Biotechnology - The results of this study support the hypothesis that several organisms that are capable of utilizing CO are also capable of degrading CO-like compounds,... 相似文献
3.
Phillips J. R. Klasson K. T. Clausen E. C. Gaddy J. L. 《Applied biochemistry and biotechnology》1993,(1):559-571
The anaerobic bacteriaClostridium ljungdahlii produces ethanol and acetate from CO, CO2, and H2 in synthesis gas. Early studies with the bacterium showed that relatively high concentrations of ethanol could be produced
by lowering the fermentation pH and eliminating yeast extract from the medium in favor of a defined medium. This article presents
the results from a medium development study based on the aerobic bacteriumEscherichia coli. The results of continuous-reactor studies in a continuously stirred tank reactor (CSTR) with and without cell recycle are
shown to demonstrate the utility of this improved medium. 相似文献
4.
Methane production from synthesis gas using a mixed culture ofR. rubrum M. barkeri,and M. formicicum
Klasson K. T. Cowger J. P. Ko C. W. Vega J. L. Clausen E. C. Gaddy J. L. 《Applied biochemistry and biotechnology》1990,(1):317-328
The components of synthesis gas, CO, H2, and CO2, may be converted into CH4 biologically through either acetate or H2/CO2 as intermediates. Of these two routes, conversion through H2/CO2 is preferred. This paper presents results of mixed-culture studies employing the photosynthetic bacteriumR. rubrum for converting CO to CO2 and H2 by the water gas shift reaction and two methanogens,M. formicicum andM. barkeri, for converting CO2 and H2 into CH4. Results are presented for triculture operation in two types of reactors, the packed bubble column and the trickle-bed reactor. 相似文献
5.
Citric acid is finding new areas of use each year and the demand for the acid is constantly increasing. Being a bulk chemical,
the continuous production of citric acid would be advantageous. The paper presents the results from ammonia limited batch
and continuous fermentations using the yeast strainSaccharomycopsis (Candida) lipolytica (NRRL Y-7576). Mathematical models were developed for growth and glucose utilization in batch and continuous culture. Cell
and acid yields appeared to be almost the same in batch and continuous culture. The specific production rates were found to
be constant, equal to 0.053 g/g h, in the batch fermentations but varied in the continuous experiments from 0 to 0.11 g/g
h depending on the fermentation conditions. Continuous production in a single stage CSTR was studied for over 1,000 hours
without shutdown. 相似文献
6.
Evans Betty S. Dudley Connie A. Klasson K. Thomas 《Applied biochemistry and biotechnology》1996,57(1):885-894
Applied Biochemistry and Biotechnology - Many industrial locations have identified the need for treatment of polychlorinated biphenyl (PCB) wastes and remediation of PCB-contaminated sites.... 相似文献
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Applied Biochemistry and Biotechnology - 相似文献
9.
Karim K Klasson KT Drescher SR Ridenour W Borole AP Al-Dahhan MH 《Applied biochemistry and biotechnology》2007,142(3):231-242
Anaerobic digestion kinetics study of cow manure was performed at 35°C in bench-scale gas-lift digesters (3.78 l working volume)
at eight different volatile solids (VS) loading rates in the range of 1.11–5.87 g l−1 day−1. The digesters produced methane at the rates of 0.44–1.18 l l−1 day−1, and the methane content of the biogas was found to increase with longer hydraulic retention time (HRT). Based on the experimental
observations, the ultimate methane yield and the specific methane productivity were estimated to be 0.42 l CH4 (g VS loaded)–1 and 0.45 l CH4 (g VS consumed)–1, respectively. Total and dissolved chemical oxygen demand (COD) consumptions were calculated to be 59–17% and 78–43% at 24.4–4.6 days
HRTs, respectively. Maximum concentration of volatile fatty acids in the effluent was observed as 0.7 g l–1 at 4.6 days HRT, while it was below detection limit at HRTs longer than 11 days. The observed methane production rate did
not compare well with the predictions of Chen and Hashimoto’s [1] and Hill’s [2] models using their recommended kinetic parameters. However, under the studied experimental conditions, the predictions of
Chen and Hashimoto’s [1] model compared better to the observed data than that of Hill’s [2] model. The nonlinear regression analysis of the experimental data was performed using a derived methane production rate
model, for a completely mixed anaerobic digester, involving Contois kinetics [3] with endogenous decay. The best fit values for the maximum specific growth rate (μ
m) and dimensionless kinetic parameter (K) were estimated as 0.43 day–1 and 0.89, respectively. The experimental data were found to be within 95% confidence interval of the prediction of the derived
methane production rate model with the sum of residual squared error as 0.02. 相似文献
10.
Klasson KT Borole AP McKeown CK Hamilton CY 《Applied biochemistry and biotechnology》2006,131(1-3):897-908
A biological process for removal of mercury from coal is under investigation. Iron and sulfur oxidizing bacteria have previously been used for desulfurization of coal and for mineral mining. We have shown that removal of mercury from coal is also possible via the same principles. Two pure cultures, Leptospirillum ferrooxidans and Acidithiobacillus ferrooxidans and four environmental consortium samples obtained from an acid mine drainage site were studied for mercury removal from coal. Four different coal samples were included in the study and the preliminary results have shown that up to 20% of the mercury can be removed in batch cultures compared to control. Additional parameters such as media composition and inoculum size were also studied. This is the first report demonstrating successful leaching of mercury from coal using biological treatment. 相似文献