Photochemical C–N bond forming reactions for the synthesis of five-membered fused N-heterocycles

Abstract

Few conversions cannot take place with ground-state reactions even with the help of a catalyst, therefore they are made to occur under photochemical conditions. The transfer of electrons took place even with the photochemical excitement of one molecule where redox reaction cannot occur at the ground state. The ground-state reactions resulted in the formation of side products. The substrates did not require any sort of chemical activation for C–N bond construction in the course of photochemical reactions. The source of energy; light has always been the interest of researchers in order to induce chemical reactions ever since the starting of scientific chemistry. The present review encloses the chemistry of photochemical transformations with a focus on their synthetic uses. The organic photochemical reactions prevent the polluting or harmful reagents thus, provides a possibility for sustainable procedures as well as green chemistry. This review article displays the formation of numerous of five-membered fused nitrogen-heterocyclic compounds.     

Ag-mediated synthesis of six-membered N-heterocycles

Abstract

One of the highly emerging and an important aspect of organic chemistry is the metal catalyzed synthesis of heterocycles. The methods used earlier for the synthesis of heterocycles were significant in the organic synthesis and developing cost-effective, improved and facial methods were beneficial to construct the complex architectures. For the both stereoselective and regioselective synthesis of six-membered nitrogen containing heterocycles, cyclic reactions that are Ag-mediated have known to be very efficient. The present review covers the applications of Ag in the formation of six-membered nitrogen containing heterocycles.     

Synthesis, electrical and thermal properties of Bi4V2−xMexO11 (x = 0.0 and 0.02) ceramics

Polycrystalline ceramic samples of Bi₄V_2?xMe_xO₁₁ (Me = Nb, Zr, Y and Cu and x = 0.0 and 0.02) have been synthesized by standard solid state reaction method using high purity oxides. The formation of the compounds have been analysed by X-ray diffraction method. The dielectric constant, dielectric loss and AC conductivity as a function of frequency and temperature have been measured. The dielectric studies indicate that the material is highly lossy and hence its AC conductivity increases with the increase of temperature. The DC conductivity of material has been measured as a function of temperature from room temperature to 380 °C and its activation energy was calculated using the relation σ = σ ₀exp (?E _a/kT). The modulated differential scanning calorimetry has been used to investigate the effect of substitution on the heat capacity and heat flow of the compounds. The results are discussed in detail.     

Strip-electromechanical model solution for piezoelectric plate cut along two semi-permeable collinear cracks

A strip electric saturation and mechanical yielding model solution is proposed for a piezoelectric plate cut along two equal collinear semi-permeable mode-I cracks with electrical polarization reaching a saturation limit and normal stress reaching a yield stress along a line segment in front of the cracks. By using Stroh formalism and complex variable technique, we derived the analytical solution for the field quantities. Three different situations are investigated when developed electrical saturation zone is bigger/smaller or equal to the developed mechanical yield zone. Numerical results show that the effect of different electric boundary conditions on the crack opening displacement and crack opening potential drop is significant and should not be ignored. The influence of electric load displacement on the energy release rate is also investigated for PZT-4, PZT-5H and BaTiO₃ ceramics, and it may assists for the correct choosing of ceramic for specific job.     

Synthesis, structural and electrical properties of La and Nb modified Bi4Ti3O12 ferroelectric ceramics

Polycrystalline ceramic samples of Bi_4−xLa_xTi₃O₁₂ (x=0.0, 0.5 and 1) and Bi_3.5La_0.5Ti_3−yNb_yO₁₂ (y=0.02 and 0.04) have been synthesized by standard high temperature solid state reaction method using high purity oxides and carbonates. The effect of lanthanum doping on Bi-site and Nb doping on Ti-site on the structural and electrical properties of Bi₄Ti₃O₁₂ powders was investigated by X-ray diffraction, scanning electron microscopy, dc conductivity and dielectric studies. A better agreement between the observed and calculated X-ray diffraction pattern was obtained by performing the Rietveld refinement with a structural model using the non-centrosymmetric space group Fmmm in all the cases. A better agreement between observed and calculated d-values also shows that the lattice parameters calculated using the Rietveld refinement analysis are better. The increase in lanthanum and niobium contents does not lead to any secondary phases. It is found that La³⁺ doping reduces the material grain size and changes its morphology from the plate-like form to a spherical staking like form. The substitution of Nb for Ti ions affected the degree of disorder and modified the dielectric properties leading to more resistive ceramic compounds. The shape and size of the grains are strongly influenced by the addition of niobium to the system. The activation energies of all the compounds were calculated by measuring their dc electrical conductivities. The frequency and temperature dependent dielectric behavior of all the compounds have also been studied and the results are discussed in detail. The substitution of La and Nb on the Bi and Ti sites decreased the T_c and improved the dielectric and ferroelectric behavior.     

New lignan glycosides from Cissus quadrangularis stems

Phytochemical investigation of Cissus quadrangularis stems led to the isolation of one new phenolic glycoside (1) and two new lignan glycosides (7 &; 8) along with twelve known compounds (2–6 &; 9–15). Their chemical structures were determined on the basis of extensive spectroscopic analysis using 1D, 2D NMR, and mass spectrometric analysis. Among the known compounds, 4–6, 9 and 12 were isolated for the first time from the genus Cissus whereas compounds 10, 11 and 13 for the first time from this plant.     

Equivalent linear stochastic seismic response of isolated bridges

Stochastic response of bridges seismically isolated by lead-rubber bearings (LRB) is investigated. The earthquake excitation is modeled as a non-stationary random process (i.e. uniformly modulated broad-band excitation). The stochastic response of isolated bridge is obtained using the time-dependent equivalent linearization technique as the force-deformation behavior of the LRB is highly nonlinear. The non-stationary response of isolated bridge is compared with the corresponding stationary response in order to study the effects of non-stationary characteristics of the earthquake input motion. For a given isolated bridge system and excitation, it was observed that there exists an optimum value of the yield strength of LRB for which the root mean square (rms) absolute acceleration of bridge deck attains the minimum value. The optimum yield strength of LRB is investigated under important parametric variations such as isolation period and damping ratio of the LRB and the frequency content and intensity of earthquake excitation. It is shown that the above parameters have significant effects on the optimum yield strength of LRB. Finally, closed-form expressions for the optimum yield strength of LRB and corresponding response of the isolated bridge system are proposed. These expressions were derived based on the model of bridge with rigid deck and pier condition subjected to stationary white-noise excitation. It was observed that there is a very good comparison between the proposed closed-form expressions and actual optimum parameters and response of the isolated bridge system. These expressions can be used for initial optimal design of seismic isolation system for the bridges.     

Cu(I)‐Catalyzed Regioselective and Highly Efficient One‐Pot Synthesis of Novel 1,2,3‐Triazoles Decorated with Pyridine and Heterocyclic Amines

An efficient one‐pot synthesis of 1,2,3‐triazoles via the three‐component coupling reaction between propargyl bromide, secondary amines, and 3‐azidopyridine in the presence of CuI as catalyst has been presented. The reaction is highly regioselective and afforded novel 1,4‐disubstituted‐1,2,3‐triazoles in excellent yields by the [3 + 2] Huisgen cycloaddition reaction. This method avoids isolation and handling of terminal acetylenes. The ease of purification has made this methodology clean and safe for the synthesis of 1,2,3‐triazoles with a broad scope.