Proposing an efficient algorithm for designing universal nanoelectronic molecular logic gates

In today's world, there are still demands for minimising the dimensions of electronic circuits, the result of which is designing nanoelectronic circuits and very small molecular gates and switches. The point which causes trouble in this design is high impact of different parameters on the performance of circuit. Despite the suggestion of simple electronic circuits and different gates, impact of parameters like length of molecule, angle between different atoms, coupling situation of electrodes to molecule, the type of atoms used in a molecule's structure and other cases has made their development almost impossible. In this paper, there was an attempt to study previous works in order to, first, mention the effects of different conditions on circuit performance and, second, present an algorithm for designing gates so as to minimise the effects of these parameters on circuit performance.     

Static and dynamic magnetic characteristics of BaCo0.5Mn0.5Ti1.0Fe10O19

The effect of Mn²⁺Co²⁺Ti⁴⁺ substitution on microwave absorption has been studied for BaCo_0.5Mn_0.5Ti_1.0Fe₁₀O₁₉ ferrite-acrylic resin composites in frequency range from 12 to 20 GHz. X-ray diffraction (XRD), scanning electron microscope (SEM), vibrating sample magnetometer, AC susceptometer and vector network analyzer were used to analyze the structural, magnetic and microwave absorption properties. The results showed that the magnetoplumbite structures for all samples have been formed. Based on microwave measurement on reflectivity, BaCo_0.5Mn_0.5Ti_1.0Fe₁₀O₁₉ may be a good candidate for electromagnetic compatibility and other practical applications at high frequency.     

Direct,Sequential, and Stereoselective Alkynylation of C,C‐Dibromophosphaalkenes

The first direct alkynylation of C,C‐dibromophosphaalkenes by a reaction with sulfonylacetylenes is reported. Alkynylation proceeds selectively in the trans position relative to the P substituent to afford bromoethynylphosphaalkenes. Owing to the absence of transition metals in the procedure, the previously observed conversion of dibromophosphaalkenes into phosphaalkynes through the phosphorus analog of the Fritsch–Buttenberg–Wiechell rearrangement is thus suppressed. The bromoethynylphosphaalkenes can subsequently be converted to C,C‐diacetylenic, cross‐conjugated phosphaalkenes by following a Sonogashira coupling protocol in good overall yields. By using the newly described method, full control over the stereochemistry at the P=C double bond is achieved. The substrate scope of this reaction is demonstrated for different dibromophosphaalkenes as well as different sulfonylacetylenes.     

Ethanolic extract of Ferula gummosa is cytotoxic against cancer cells by inducing apoptosis and cell cycle arrest

Ferula gummosa Boiss. has medicinal applications in treating a wide range of diseases including cancer. The objective of this study was to evaluate the antiproliferative activities of the seed and gum extracts of F. gummosa as well as to study the effect of the potent extract on the induction of apoptosis and cell cycle arrest. Our results demonstrated that the ethanolic extract had the lowest IC₅₀ value at 72 h (0.001 ± 1.2 mg/mL) in BHY cells. Moreover, flowcytometry and annexin-V analysis revealed that the ethanolic extract induced apoptosis and cell-cycle arrest in BHY cells at G1/S phase. In addition, colorimetric methods exhibited the highest amount of total phenolics and flavonoids in the aqueous and gum extracts (0.12 ± 0.037, 0.01 ± 2.51 mg/g of dry powder). Generally, the results obtained indicate that F. gummosa ethanol extract may contain effective compounds which can be used as a chemotherapeutic agent.