Direct synthesis of Cbz-protected β-amino ketones by iodine-catalyzed three-component condensation of aldehydes, ketones and benzyl carbamate

Iodine has been found to be very effective catalyst for a Mannich reaction between an aryl aldehyde, an aryl ketone and benzyl carbamate, even though this is a less reactive amine, to produce Cbz-protected β-aryl β-amino carbonyl compounds in high yields.     

A simple and efficient method for regioselective and stereoselective synthesis of vicinal bromohydrins and alkoxybromides from an olefin

A very rapid and efficient method has been developed for the synthesis of vicinal bromohydrins and alkoxybromides directly from an olefin without any catalyst. The reaction was performed in CH3CN-water (4:1) or alcohol using N,N-dibromo-p-toluenesulfonamide (TsNBr2) as the brominating agent. Excellent yields and regio- and stereoselectivities have been obtained. Bromohydrins are formed instantaneously, whereas formation of alkoxybromides takes 30-60 min.     

Iodine-catalyzed one-pot three-component synthesis of homoallyl benzyl ethers from aldehydes

Iodine has been found to be an effective catalyst for one-pot synthesis of homoallyl benzyl ethers under mild reaction conditions. Various homoallyl benzyl ethers were synthesized in moderate to high yield by three-component condensation of aldehydes, benzyloxytrimethylsilane, and allyltrimethylsilane in presence of iodine (10 mol %) in dichloromethane at 0 °C.     

Detailed physicochemical and thermochemical investigation of Upper Assam oil shale

Journal of Thermal Analysis and Calorimetry - The present work provides a detailed characterization and kinetic study of oil shale of Upper Assam, India. The physicochemical characteristics of oil...