Self-assembly of double stranded dinuclear titanium(IV)-Schiff base complexes and formation of intramolecular mu-oxo bridges

The reaction of titanium isopropoxide with a Schiff base ligand containing an isobutenyl linker leads to double stranded dinuclear titanium(IV)-Schiff base complexes through self-assembly with concomitant formation of intramolecular mu-oxo bridges upon hydrolysis.     

Palladium catalyzed atom-efficient cross-coupling reactions of triarylbismuths with aryl bromides

Aryl bromides (3 equiv) were coupled efficiently with triarylbismuths (1 equiv) in an atom-efficient way using the Pd(OAc)₂/PPh₃ catalytic system in the presence of K₃PO₄ as base in DMF at 90 °C, providing excellent yields of the cross-coupled biaryls in short reaction times.     

A new palladium catalyzed protocol for atom-efficient cross-coupling reactions of triarylbismuths with aryl halides and triflates

A new palladium catalyzed protocol for an atom-efficient cross-coupling reaction of triarylbismuths with aryl halides and triflates has been described. The palladium catalytic system with Cs₂CO₃ base was found to be very efficient in DMA solvent to furnish excellent yields of cross-coupled functionalized biaryls in short reaction times.     

Metal catalyst-free direct α-iodination of ketones with molecular iodine

Ketones are directly converted to the corresponding α-iodoketones in good yields with molecular iodine under metal catalyst-free conditions. A significant difference in the reactivities was observed for aliphatic and aromatic ketones; whereas aliphatic ketones reacted smoothly at room temperature giving a mixture of 1-iodo, 3-iodo and 1,3-diiodoketones with predominant formation of the 3-iodo product, the α-iodination of aromatic ketones proceeded conveniently under heating to give good yields of α-iodo products.     

Pd-catalyzed synthesis of α-aryl ketones through couplings of α-arylacetyl chlorides with triarylbismuths as multi-coupling nucleophiles

The cross-coupling reaction of α-arylacetyl chlorides with triarylbismuths was studied under Pd-catalyzed conditions. The reaction was found to be facile under the established protocol and furnished high yields of α-aryl ketones in short reaction times. This work also demonstrated a facile synthesis of various regio-isomeric mono-, di- and tri-substituted α-aryl ketones in high yields. Triarylbismuths were employed as sub-stoichiometric multi-coupling organometallic nucleophiles in this coupling protocol.     

An atom-efficient palladium-catalyzed cross-coupling reaction of triarylbismuths with acid chlorides: synthesis of diaryl and alkyl aryl ketones

The cross-coupling reaction of triarylbismuths with acid chlorides using a catalytic amount of PdCl₂/PPh₃ afforded the corresponding ketones in high yields. The reactions of aromatic and aliphatic acid chlorides occurred with atom efficiency, as 3 equiv of acid chlorides coupled effectively with 1 equiv of triarylbismuths to yield 3 equiv of the corresponding diaryl and alkyl aryl ketones.     

Palladium catalyzed atom-efficient cross-coupling reactions of triarylbismuths with aryl iodides and aryl triflates

The atom-efficient cross-coupling of triarylbismuths with aryl iodides or aryl triflates using catalytic Pd(OAc)₂/PPh₃ and K₃PO₄ as base in DMF at 90 °C to afford the corresponding functionalized biaryls in high yields is reported.     

Oxalyl chloride as carbonyl synthon in Pd-catalyzed carbonylations of triarylbismuth and triarylindium organometallic nucleophiles

Oxalyl chloride has been demonstrated to function as C1 carbonyl synthon in the carbonylations of triarylbismuth and triarylindium nucleophiles under palladium-catalyzed conditions. All the three aryl groups from both bismuth and indium reagents participated in carbonylative couplings to afford the corresponding functionalized ketones in high yields. This study also disclosed a novel utilization of oxalyl chloride as facile alternative source of CO for carbonylations under palladium catalysis.     

Pd-catalyzed coupling of aryl iodides with triarylbismuths as atom-economic multi-coupling organometallic nucleophiles under mild conditions

The facile cross-coupling reactivity of triarylbismuth compounds with aryl iodides was achieved under mild heating conditions. The established catalytic protocol using Pd(OAc)₂(Cy₂NH)₂ system exhibited high coupling reactivity with a variety of triarylbismuth and aryl iodide compounds under mild conditions. These coupling reactions were completed in short reaction time affording good to high yields of functionalized biaryl products. The studies of multi-coupling reactions with tris(4-iodophenyl)amine, 8 also furnished moderate to good yields of coupled products, 8a-8f.