Dihedral angle study in Hesperidin using NMR Spectroscopy

Hesperidin is flavonoid molecule found in citrus fruits (Citrus reticulata), especially difficult to extract, classify and characterize. Present work is to study the unresolved relative configuration of Hesperidin through the dihedral angle, coupling constant and different NMR techniques. The Karplus equation and its modifications have been originated from the valence bond theory and associated with dihedral angle and coupling constant. The result data set of calculated dihedral angle can probe significant method to assign the virtual configuration of natural products and also resolved stereochemistry of Hesperidin at C‐2 position in. Copyright © 2016 John Wiley & Sons, Ltd.     

Synthesis of Lanso Aminopyrimidines as Dominant Chemotherapeutic Agents for Leukaemia

Russian Journal of Organic Chemistry - In the present paper we synthesized 10 unique pyrimidine scaffolds (Lanso Aminopyrimidines) derived from...     

Green Regioselective Synthesis of (Purin-6-yl)hydrazones

Russian Journal of Organic Chemistry - Some unique purine hydrazinylidene derivatives were synthesized by the regioselective reaction of 2,6-dichloropurine with hydrazine hydrate, followed by...     

Copper(I)-Catalyzed Click Chemistry-Based Synthesis and Antimicrobial Evaluation of Triazolopyridine–Triazole Congeners

Russian Journal of Organic Chemistry - In an effort to find a new pharmacologically dynamic molecule, we report here the synthesis and in vitro antimicrobial activity of...     

Synthesis,Characterization, and Antimicrobial Evaluation of New Imidazo[2,1-b][1,3,4]thiadiazoles Bearing a Chroman Moiety

Russian Journal of Organic Chemistry - A series of 6-aryl-2-(6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl)imidazo[2,1-b][1,3,4]thiadiazoles were synthesized through a two-step procedure. The structure...