全文获取类型
收费全文 | 15404篇 |
免费 | 2354篇 |
国内免费 | 1816篇 |
专业分类
化学 | 11232篇 |
晶体学 | 206篇 |
力学 | 857篇 |
综合类 | 154篇 |
数学 | 1878篇 |
物理学 | 5247篇 |
出版年
2024年 | 51篇 |
2023年 | 306篇 |
2022年 | 533篇 |
2021年 | 561篇 |
2020年 | 683篇 |
2019年 | 626篇 |
2018年 | 532篇 |
2017年 | 561篇 |
2016年 | 793篇 |
2015年 | 807篇 |
2014年 | 917篇 |
2013年 | 1211篇 |
2012年 | 1424篇 |
2011年 | 1393篇 |
2010年 | 998篇 |
2009年 | 908篇 |
2008年 | 986篇 |
2007年 | 831篇 |
2006年 | 748篇 |
2005年 | 629篇 |
2004年 | 553篇 |
2003年 | 467篇 |
2002年 | 498篇 |
2001年 | 375篇 |
2000年 | 269篇 |
1999年 | 305篇 |
1998年 | 176篇 |
1997年 | 151篇 |
1996年 | 167篇 |
1995年 | 130篇 |
1994年 | 111篇 |
1993年 | 119篇 |
1992年 | 100篇 |
1991年 | 93篇 |
1990年 | 59篇 |
1989年 | 62篇 |
1988年 | 51篇 |
1987年 | 36篇 |
1986年 | 48篇 |
1985年 | 47篇 |
1984年 | 25篇 |
1983年 | 12篇 |
1982年 | 21篇 |
1981年 | 13篇 |
1980年 | 13篇 |
1979年 | 16篇 |
1978年 | 13篇 |
1959年 | 12篇 |
1958年 | 11篇 |
1957年 | 17篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
Kang Il Yoo Ji Yeong Jeon Su Jeong Ryu Giri Nam Hyewon Youn Eun Young Choi 《Experimental & molecular medicine》2015,47(2):e140
In allogeneic transplantation, including the B6 anti-BALB.B settings, H60 and H4 are two representative dominant minor histocompatibility antigens that induce strong CD8 T-cell responses. With different distribution patterns, H60 expression is restricted to hematopoietic cells, whereas H4 is ubiquitously expressed. H60-specific CD8 T-cell response has been known to be dominant in most cases of B6 anti-BALB.B allo-responses, except in the case of skin transplantation. To understand the mechanism underlying the subdominance of H60 during allogeneic skin transplantation, we investigated the dynamics of the H60-specific CD8 T cells in B6 mice transplanted with allogeneic BALB.B tail skin. Unexpectedly, longitudinal bioluminescence imaging and flow cytometric analyses revealed that H60-specific CD8 T cells were not always subdominant to H4-specific cells but instead showed a brief dominance before the H4 response became predominant. H60-specific CD8 T cells could expand in the draining lymph node and migrate to the BALB.B allografts, indicating their active participation in the anti-BALB.B allo-response. Enhancing the frequencies of H60-reactive CD8 T cells prior to skin transplantation reversed the immune hierarchy between H60 and H4. Additionally, H60 became predominant when antigen presentation was limited to the direct pathway. However, when antigen presentation was restricted to the indirect pathway, the expansion of H60-specific CD8 T cells was limited, whereas H4-specific CD8 T cells expanded significantly, suggesting that the temporary immunodominance and eventual subdominance of H60 could be due to their reliance on the direct antigen presentation pathway. These results enhance our understanding of the immunodominance phenomenon following allogeneic tissue transplantation. 相似文献
2.
The ability of bottlebrush block copolymers (BBCPs) to self-assemble into ordered large periodic structures could greatly expand the scope of photonic and membrane technologies. In this paper, we describe a two-step synthesis of poly(l-lactide)-b-polystyrene (PLLA-b-PS) BBCPs and their rapid thin-film self-assembly. PLLA chains were grown from exo-5-norbornene-2-methanol via ring-opening polymerization (ROP) of l-lactide to produce norbornene-terminated PLLA. Norbonene-terminated PS was prepared using anionic polymerization followed by a termination reaction with exo-5-norbornene-2-carbonyl chloride. PLLA-b-PS BBCPs were prepared from these two norbornenyl macromonomers by a one-pot sequential ring opening metathesis polymerization (ROMP). PLLA-b-PS BBCPs thin-films exhibited cylindrical and lamellar morphologies depending on the relative block volume fractions, with domain sizes of 46–58 nm and periodicities of 70–102 nm. Additionally, nanoporous templates were produced by the selective etching of PLLA blocks from ordered structures. The findings described in this work provide further insight into the controlled synthesis of BBCPs leading to various possible morphologies for applications requiring large periodicities. Moreover, the rapid thin film patterning strategy demonstrated (>5 min) highlights the advantages of using PLLA-b-PS BBCP materials beyond their linear BCP analogues in terms of both dimensions achievable and reduced processing time. 相似文献
3.
Nováková Kateřina Hrdlička Vojtěch Navrátil Tomáš Vyskočil Vlastimil Barek Jiří 《Monatshefte für Chemie / Chemical Monthly》2015,146(5):761-769
Monatshefte für Chemie - Chemical Monthly - The voltammetric behavior of 5-nitroindazole was investigated at polished (p-AgSAE) and at mercury meniscus-modified (m-AgSAE) silver solid amalgam... 相似文献
4.
5.
浅析二阶齐次线性变系数微分方程的一个可积类型 总被引:1,自引:0,他引:1
姬志飞 《应用数学与计算数学学报》2006,20(1):125-128
本文讨论了二阶齐次线性变系数微分方程的特殊形式,给出了这种微分方程的一个可积类型. 相似文献
6.
7.
Based on the Collins formula and irradiance moments definition, the propagation of the kurtosis parameter of super-Gaussian beams through a spherically aberrated lens is studied. Detailed numerical results are given. It is shown that, as compared with aberration-free super-Gaussian beams, the profile of spherically aberrated super-Gaussian beams can be leptokurtic, mesokurtic or platykurtic, depending on the aberration and propagation distance. The results for the spherically aberrated Gaussian beams can be dealt with as a special case treated in this paper. Finally, the advantage of our method is pointed out. 相似文献
8.
Summary Some estimators of maximum likelihood type are constructed for estimating functionals of one-dimensional Gibbs states. We also show that those estimators are strongly consistent, asymptotically normal and asymptotically efficient. 相似文献
9.
10.
Burn‐in is a widely used method to improve the quality of products or systems after they have been produced. In this paper, we consider the problem of determining the optimal burn‐in time and optimal work size maximizing the long‐run average amount of work saved per time unit in the computer applications. Assuming that the underlying lifetime distribution of the computer has an initially decreasing or/and eventually increasing failure rate function, an upper bound for the optimal burn‐in time is derived for each fixed work size and a uniform (with respect to the burn‐in time) upper bound for the optimal work size is also obtained. Furthermore, it is shown that a non‐trivial lower bound for the optimal burn‐in time can be derived if the underlying lifetime distribution has a large initial failure rate. Copyright © 2005 John Wiley & Sons, Ltd. 相似文献