Isolation and structure determination of a new thiopeptide globimycin from Streptomyces globisporus subsp. globisporus based on genome mining

Based on genome-mining, a new thiopeptide globimycin was discovered from the extract of Streptomyces globisporus subsp. globisporus, along with known one radamycin. The structure of globimycin was established by a combination of 2D NMR and ESI-MS experiments, and globimycin was identified to be a structural isomer of a known thiopeptide methylsulfomycin. The proposed biosynthetic gene cluster for globimycin and radamycin was found in the genome of S. globisporus subsp. globisporus.     

Polymeric Membrane Nanofiltration and Its Application to Separations in the Chemical Industries

The application of membrane technology, particularly water-based nanofiltration, as a separation process in the chemical industries has increased tremendously in recent years. However, the use of membranes capable of molecular separation in non-aqueous systems (e.g. nanofiltration) is a relatively new and growing application of membrane technology. The main challenge in applying polymeric nanofiltration membranes to non-aqueous systems is that the polymers developed for water-based applications are not suitable. Polyimide is a particularly interesting polymer as it has excellent chemical resistance, and membranes produced from it provide desirable separation properties – i.e. economically viable flux and good separation of nanoscale molecules. Various research works have shown that commercial polyimide organic solvent nanofiltration (OSN) membranes, trademark STARMEM™, 1 are robust and suitable for performing molecular separations. This work will discuss in detail the use of STARMEM™ in a pharmaceutical application. The EIC-OSN process was developed for separating the enantiomers of chiral compounds in pharmaceutical applications. High optical purity (94.9%) of (S)-phenylethanol from rac-phenylethanol was achieved through the use of STARMEM™122. Process simulation of the ideal eutomer-distomer system predicted that the highest theoretical resolvability from this process would be 99.2%. Other application areas of OSN are varied, including purification and fractionation in the natural products industry, homogeneous catalyst recovery, monomer separation from oligomers, etc. Currently, OSN is used in a small number of processes including a very large petrochemical application, but it has the potential to be applied to a wide range of separations across the full spectrum of the chemical industries.     

Strong convergence theorems by hybrid method for asymptotically -strict pseudo-contractive mapping in Hilbert space

In this paper, we introduce the hybrid method of modified Mann’s iteration for an asymptotically k-strict pseudo-contractive mapping. Then we prove that such a sequence converges strongly to P_F(T)x₀. This main theorem improves the result of Issara Inchan [I. Inchan, Strong convergence theorems of modified Mann iteration methods for asymptotically nonexpansive mappings in Hilbert spaces, Int. J. Math. Anal. 2 (23) (2008) 1135–1145] and concerns the result of Takahashi et al. [W. Takahashi, Y. Takeuchi, R. Kubota, Strong convergence theorems by hybrid methods for families of nonexpansive mappings in Hilbert space, J. Math. Anal. Appl. 341 (2008) 276–286], and many others.     

Strong convergence theorems of hybrid methods for two asymptotically nonexpansive mappings in Hilbert spaces

In this paper, we introduce two modifications of the Ishikawa iteration, by using the hybrid methods, for asymptotically nonexpansive mappings and asymptotically nonexpansive semigroups in a Hilbert space. Then, we prove that such two sequences converge strongly to common fixed points of two symptotically nonexpansive mappings and asymptotically nonexpansive semigroups, respectively. Our main result is connected with the results of Plubtieng and Ungchittrakool [S. Plubtieng, K. Ungchittrakool, Strong convergence of modified Ishikawa iteration for two asymptotically nonexpansive mappings and semigroups, Nonlinear. Anal. 67(2007) 2306-2315], Martinez-Yanes and Xu [C. Martinez-Yanes, H.K. Xu, Strong convergence of CQ method for fixed point iteration processes, Nonlinear. Anal. 64 (2006) 2400-2411] and many others.     

Hybrid extragradient method for general equilibrium problems and fixed point problems in Hilbert space

In this paper, we introduce an iterative scheme by the hybrid methods for finding a common element of the set of fixed points of nonexpansive mappings, the set of solutions of an equilibrium problem and the set of solutions of a variational inequality problem in a Hilbert space. Then, we prove the strongly convergent theorem by a hybrid extragradient method to the common element of the set of fixed points of nonexpansive mappings, the set of solutions of an equilibrium problem and the set of solutions of a variational inequality problem. Our results extend and improve the results of Bnouhachem et al. [A. Bnouhachem, M. Aslam Noor, Z. Hao, Some new extragradient iterative methods for variational inequalities, Nonlinear Analysis (2008) doi:10.1016/j.na.2008.02.014] and many others.