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1.
To achieve efficient proton pumping in the light-driven proton pump bacteriorhodopsin (bR), the protein must be tightly coupled to the retinal to rapidly convert retinal isomerization into protein structural rearrangements. Methyl group dynamics of bR embedded in lipid nanodiscs were determined in the dark-adapted state, and were found to be mostly well ordered at the cytosolic side. Methyl groups in the M145A mutant of bR, which displays only 10 % residual proton pumping activity, are less well ordered, suggesting a link between side-chain dynamics on the cytosolic side of the bR cavity and proton pumping activity. In addition, slow conformational exchange, attributed to low frequency motions of aromatic rings, was indirectly observed for residues on the extracellular side of the bR cavity. This may be related to reorganization of the water network. These observations provide a detailed picture of previously undescribed equilibrium dynamics on different time scales for ground-state bR.  相似文献   
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The lattice profile analyzes the intrinsic structure of pseudorandom number sequences with applications in Monte Carlo methods and cryptology. In this paper, using the discrete Fourier transform for periodic sequences and the relation between the lattice profile and the linear complexity, we give general formulas for the expected value, variance, and counting function of the lattice profile of periodic sequences with fixed period. Moreover, we determine in a more explicit form the expected value, variance, and counting function of the lattice profile of periodic sequences for special values of the period.  相似文献   
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Properties of the unions of sampling and interpolation sets for Bergman spaces are discussed in conjunction with the examples given by Seip (1993). Their relationship to the classical interpolation sequences is explored. In addition, the role played by canonical divisors in the study of these sets is examined and an example of a sampling set is constructed in the disk.

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We consider optimal control problems for systems described by stochastic differential equations with delay. We state conditions for certain classes of such systems under which the stochastic control problems become finite-dimensional. These conditions are illustrated with three applications. First, we solve some linear quadratic problems with delay. Then we find the optimal consumption rate in a financial market with delay. Finally, we solve explicitly a deterministic fluid problem with delay which arises from admission control in ATM communication networks.  相似文献   
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In this paper we present an analytical model, which considers the effects of the switching time on the network performance in service differentiated optical packet/burst switching (OPS/OBS) networks. Our results indicate that the switching time must be less than 10 % of the packet/burst duration in order to avoid any significant reductions in the network performance. Furthermore, regarding a network with full wavelength conversion, we show that the benefits of statistical resource sharing are almost non-existent for low priority traffic when the switching time is large.  相似文献   
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Optical spectroscopy in combination with wide field or confocal optical microscopy enables the investigation of single quantum objects such as organic molecules, II/VI semiconductor quantum dots and silicon nanocrystals. They all have fluctuations of luminescence intensities on time scales longer than μs in common. A comparison reveals that despite the large differences of the nature of the respective quantum objects, the intensity fluctuations are related to a slow ionisation process followed by a trapping of the photoejected charge in the non-conducing environment. Detailed aspects of the dynamics are controlled by the dielectric properties of the matrix.  相似文献   
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Let Ω be a region in ℝn and letp = Pi ) i 1m , be a partition ofΩ into a finite number of closed subsets having piecewise C2 boundaries of finite(n - 1 )dimensional measure. Let τ:Ω→Ω be piecewise C2 onP where, τi = τ|pi is aC 2 diffeomorphism onto its image, and expanding in the sense that there exists α > 1 such that for anyi = 1, 2,...,m ‖Dτi -1 ‖ < α-1, where Dτi -1 is the derivative matrixτ i - 1 and |‖·‖ is the Euclidean matrix norm. By means of an example, we will show that the simple bound of one-dimensional dynamics cannot be generalized to higher dimensions. In fact, we will construct a piecewise expanding C2 transformation on a fixed partition with a finite number of elements in ℝ2, but which has an arbitrarily large number of ergodic, absolutely continuous invariant measures  相似文献   
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