Metathesis of hex-1-ene in ionic liquids catalyzed by WCl6

Metathesis of hex-1-ene in ionic liquids catalyzed by WCl₆ was studied. The metathesis is preceded by isomerization of hex-1-ene to hex-2-ene, from which the main reaction product, viz., oct-4-ene, is derived. The WCl₆-1-butyl-3-methylimidazolium tetrafluoroborate (BMIM·BF₄) system efficiently catalyzes metathesis of linear olefin, the ionic liquid serving as the reaction medium by forming a stable homogeneous catalytic system with WCl₆. The yields of the metathesis products increase with increasing reaction temperature. The addition of tin-containing promoters leads to a substantial increase in the reaction rate. In the WCl₆-BMIM·BF₄-SnBu₄ system, the selectivity of the formation of oct-4-ene is significantly enhanced.__________Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 10, pp. 2094–2097, October, 2004.     

Investigation of thermal transformations of propylene and its role in the formation of benzene by pyrolysis of n-hexane

Conclusions We investigated the thermal transformations of propylene and mixtures of n-hexane and propylene at 800C by use of radioactive hydrocarbons labeled with¹⁴C. The data obtained lead to the conclusion that on pyrolysis of n-hexane benzene is formed by the interaction of propylene with 1,3-butadiene or by intermediate formation of 1,3-butadiene.Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 7, pp. 1556–1560, July, 1984.     

On the adsorption mechanism of copper ions on bentonite clay

Russian Chemical Bulletin - The adsorption of copper ions on bentonite clay was studied as a function of the pH of the medium, contact time, and temperature. A comparative study of the...     

Selective Targeting of Breast Cancer by Tafuramycin A Using SMA-Nanoassemblies

Triple-negative breast cancer (TNBC) is a heterogeneous subtype of tumors that tests negative for estrogen receptors, progesterone receptors, and excess HER2 protein. The mainstay of treatment remains chemotherapy, but the therapeutic outcome remains inadequate. This paper investigates the potential of a duocarmycin derivative, tafuramycin A (TFA), as a new and more effective chemotherapy agent in TNBC treatment. To this extent, we optimized the chemical synthesis of TFA, and we encapsulated TFA in a micellar system to reduce side effects and increase tumor accumulation. In vitro and in vivo studies suggest that both TFA and SMA–TFA possess high anticancer effects in TNBC models. Finally, the encapsulation of TFA offered a preferential avenue to tumor accumulation by increasing its concentration at the tumor tissues by around four times in comparison with the free drug. Overall, the results provide a new potential strategy useful for TNBC treatment.     

Adsorption of phenol and 2,4-dichlorophenol on carbon-containing sorbent produced from sugar cane bagasse

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