Efficient Synthesis of Structurally Novel Diaryl Ethers by Regioselective Functionalization

Synthesis of structurally novel and biologically useful 3′-substituted diaryl ethers employing Cu(0) as a catalyst, followed by regioselective either sulfonylation or carbonylation, is described.     

Investigation of interaction strategies between pyrazolone dyes and poly(acrylamide-co-acrylic acid)

The removal of dyes from waste water before their discharge into aquatic ecosystems is of substantial concern. Amongst functional macromolecules, the combination of polymers with dyes is a research field of enormous potential with regard to high-performance materials. The present study investigates interactions strategies between P(AM-co-AA) polymer with pyrazolone azo dyes in water as green solvent. These interactions were confirmed by FTIR spectroscopy, Ultra-visible spectroscopy, EDAX analysis, and FE-SEM analysis. Polymer P(AM-co-AA) has porous structure in which dyes present in the water get absorb hence it is use to remove pyrazolone dyes from water.

     

Convenient Synthesis of Structurally Novel 1,3‐Disubstituted Azetidine Derivatives

A convenient synthesis of structurally novel 1,3‐disubstituted azetidine derivatives is described. The approach involves condensation of an azetidine building block with sulfonylated carbamic acid methyl ester, subsequently followed by quenching the imidoyl chloride with amines. Different derivatives were prepared by substituting benzhydrol as well as benzenesulfonamide as part of the core structure.     

Novel and Efficient Synthesis of tert-Butyl-2-(4-(2-aminoethyl)phenylthio)-2-methylpropanoate,a Key Intermediate in the Synthesis of Ureido Thioisobutyric Acid

A convenient and cost-effective synthesis of pharmacologically important tert-butyl-2-(4-2-aminoethyl)phenylthio)-2-methylpropanoate from commercially available 2-2-phenyl-1-ethanol is described.     

Bis(2-Hydroxy-3-Isopropyl-6-Methyl-Benzaldehyde)Ethylenediamine: A Novel Cation Sensor

Novel substituted phenol-based new symmetrical bis(2-hydroxy-3-isopropyl-6-methyl-benzaldehyde)ethylenediamine (1) has been designed and synthesized. The compound 1 fluorometrically recognized Cu²⁺ ion in CH₃OH/H₂O (90:10, v/v) by exhibiting an increase in emission upon complexation. In addition, Cu²⁺ gave rise to a change in colour of the solution of compound 1, which was clearly visible to the naked eye under UV irradiation. The association constant (K) of compound 1 with Cu²⁺ ion was computed with the Benesi-Hildebrand plot and Scatchard plot at 43,000 M^?1 and 43,011 M^?1 respectively.