Reaction of Chloroacetone with Cytisine and d-Pseudoephedrine Alkaloids

Alkylation of cytisine and d-pseudoephedrine alkaloids with chloroacetone was performed. The target product of the reaction with cytisine is aminoacetone and of the reaction with d-pseudoephedrine, a morpholine derivative.     

Thermochemistry of potassium morpholinodithiocarbamate

Results of thermochemical studies of a new compound, potassium morpholinodithiocarbamate, are presented. The enthalpies of its solution in water at various dilutions and the specific heat at 173–348 K were examined by the experimental methods of isothermal and dynamic calorimetry.     

Crystal and molecular structure of 2e-diethylamino-3e,4e-dimethyl-5e-phenyl-2a-thio-1,3,2-oxazaphospholane

The results of an x-ray structural investigation of 2e-diethylamino-3e,4e-dimethyl-5e-phenyl-2a-thio-1,3,2-oxazaphospholane are discussed. It has been shown that the conformation of the 5-membered ring is that of a half-chair.Institute of Organic Synthesis and Coal Chemistry, Kazkh SSR Academy of Sciences, Karganda. A. N. Nesmeyanov Institute of Heteroorganic Compounds, USSR Academy of Sciences, Moscow. Translated from Khimiya Prirodnykh Soedinenii, No. 3, pp. 386–389, May–June, 1990.     

Synthesis and acute toxicity of some phosphorylated derivatives of ephedrine alkaloids

The results are given of the synthesis and a comparative study of the toxicities of some phosphorylated derivatives of the alkaloids l-ephedrine and d-pseudoephedrine. It has been shown that the introduction of phosphorus- and sulfur-containing fragments considerably lowers the toxicity of the alkaloids. Institute of Organic Synthesis and Coal Chemistry, National Academy of Sciences of the Republic of Kazakhstan, Karaganda. Translated from Khimiya Prirodnykh Soedinenii, No. 3, pp. 406–408, May–June, 1994.     

Reactions of dithiocarbamic acids derived from alkaloids, morpholine, and piperidine with acrylic acid and its derivatices

-(Thiocarbamoylthio)propionic acids derived from alkaloids, morpholine, and piperidine and their esters, amides, and nitriles were prepared by reactions of the corresponding dithiocarbamic acids with acrylic acid and its derivatives. Some of the compounds were tested for insecticidal activity.Translated from Zhurnal Prikladnoi Khimii, Vol. 77, No. 8, 2004, pp. 1336–1339.Original Russian Text Copyright © 2004 by Zhivotova, Gazaliev, Ibraev, Fazylov, Kasenov.     

Electrochemical extraction of alkaloids from ephedra herbage

The process of extracting ephedra herbage in a constant electric field has been studied. It has been shown that the application of an electric field considerably accelerates the isolation of the alkaloid molecules from the cellulose of the plant raw material. The main kinetic characteristics of the electroextraction of the total alkaloids as functions of various factors have been obtained.Institute of Organic Synthesis and Coal Chemistry, Kazakh SSR Academy of Sciences, Karaganda. Translated from Khimiya Prirodnykh Soedinenii, No. 6, pp. 862–864, November–December, 1987.     

Thermodynamic Properties of Salsoline Salsolinodithiocarbamate

Heat of solution of salsoline salsolinodithiocarbamate (SS) at 1 : 18 000, 1 : 36 000, and 1 : 72 000 dilution (mol per mol H₂O) was determined on a DAK-I-IA calorimeter, and the standard heat of solution at infinite dilution was estimated. The temperature dependence of the heat capacity of SS was studied over the range 173–348 K. The heats of combustion and fusion, and the standard heat of formation of liquid (molten) and crystalline SS were estimated by indirect methods.     

Synthesis and Structure of Cytisinyl(β-chloro-β-phenylvinyl)phosphinic Esters

2-Propynyl, ethyl, and isopropyl cytisinyl(β-chloro-β-phenylvinyl)phosphinates were synthesized, and their structure was determined by X-ray analysis.__________Translated from Zhurnal Organicheskoi Khimii, Vol. 41, No. 6, 2005, pp. 917–919.Original Russian Text Copyright © 2005 by Zhivotova, Gazaliev, Fazylov, Karimova, D. Turdybekov, K. Turdybekov.     

Synthesis and anticholinesterase activities of O-phosphorylated derivatives ofd-allylpseudoephedrine

An immunochemical investigation has been made of the culture liquid after the cultivation of ten strains of the microorganisms Yersinia pseudotuberculosis. It has been shown that in the process of vital activity all the strains investigated, to a greater or smaller degree, produce into the culture medium products of catabolic breakdown consisting of fragments of receptor proteins which are possibly, regulators of metabolic processes taking place under the influence of the constantly changing conditions of the growth medium.Pacific Ocean Institute of Bioorganic Chemistry, Far Eastern Branch, Russian Academy of Sciences, Vladivostok. Translated from Khimiya Prirodnykh Soedinenii, No. 3, pp. 436–439, May–June, 1993.     

Anodic behavior of ephedrine at solid electrodes

The electrooxidation of the alkaloid ephedrine at solid electrodes in a wide range of concentrations and pH values of solutions has been studied by the methods of potentiodynamic voltammetric curves, preparative electrolysis, and quantum-chemical calculations by the SCF MO LCAO method in the MINDO/3 approximation. A quantitative basis has been given for the sequence of stages in the electrooxidation of ephedrine proposed previously by the authors of one of the cited papers. Good agreement has been established between the values found theoretically and experimentally. Institute of Organic Synthesis and Colloid Chemistry, Kazakh SSR Academy of Sciences, Karaganda. Translated from Khimiya Prirodnykh Soedinenii, No. 4, pp. 523–526, July–August, 1989.