The interaction of erythromycin with polymeric sorbents adjusted to the antibiotic molecule

Cross-linked carboxylic cationites adjusted to sorption of the antibacterial antibiotic erythromycin were obtained by radical copolymerization of methacrylic acid, erythromycin methacrylate, and ethylene glycol dimethacrylate as a cross-linking agent. Studies of the sorption and desorption of erythromycin showed that adjusted sorbents had favorable equilibrium and kinetic characteristics of sorption and the ability to reversibly desorb the antibiotic. Original Russian Text ? O.A. Pisarev, N.M. Ezhova, I.S. Garkushina, 2009, published in Zhurnal Fizicheskoi Khimii, 2009, Vol. 83, No. 1, pp. 142–146.     

Dynamics of Uric Acid Sorption on Molecularly Imprinted Sorbent

Russian Journal of Applied Chemistry - In order to create an effective sorption method for extracting uric acid from blood plasma, the dynamics of uric acid sorption by a granular molecular...     

Equilibrium sorption properties of cholesterol surface-imprinted Se-containing polymeric sorbents synthesized by Pickering emulsion polymerization

The equilibrium sorption isotherms of cholesterol on surface-imprinted Se-containing sorbents based on 2-hydroxyethyl methacrylate and ethylene glycol dimethacrylate were studied. The equilibrium sorption of cholesterol occurred on a homogeneous sorption surface of the molecularly imprinted polymer (template content 6 mol.%). The sorption surface had a higher affinity to template molecules compared to the monolayer. An increase in the amount of template introduced during modification of the polymer matrix led to an increase in the sorption surface area of solvated polymers available for cholesterol binding.

     

Exchange reactions of urethanes with proton-donating compounds: Kinetics of the reactions of phenyl-<Emphasis Type="Italic">N</Emphasis>-phenylurethane with butyl alcohols

The exchange reactions of phenyl-N-phenylurethane with aliphatic alcohols, namely, n-butyl, sec-butyl, and tert-butyl alcohols, in ortho-dichlorobenzene and in the media of the corresponding alcohols were studied. In the absence of a catalyst and proton-donating compounds, the monomolecular cleavage of phenyl-N-phenylurethane to isocyanate and alcohol proceeds at a noticeable rate starting only at 250°C. Between 40 and 80°C, the exchange reactions take place via direct exchange between urethane and the photon-donating compound and are second-order up to high conversions (until the almost complete disappearance of the initial urethane). Activation energies and apparent rate constants have been determined for the exchange reactions of phenyl-N-phenylurethane with butyl alcohols. The rates of the exchange reactions in the alcohol medium are compared with those in ortho-dichlorobenzene.