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By combining the total cell evolution curve and a two-compartment model interacting with dynamic anti-cancer agents, the evolution of subpopulations has been analytically obtained and investigated in this work.  相似文献   
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A novel sensitive method for detection of DNA methylation was developed with thioglycollic acid (TGA)-capped CdTe quantum dots (QDs) as fluorescence probes. Recognition of methylated DNA sites would be useful strategy due to the important roles of methylation in disease occurrence and developmental processes. DNA methylation occurs most often at cytosine-guanine sites (CpG dinucleotides) of gene promoters. The QDs significantly interacted with hybridized unmethylated and methylated DNA. The interaction of CpG rich methylated and unmethylated DNA hybrid with quantum dots as an optical probe has been investigated by fluorescence spectroscopy and electrophoresis assay. The fluorescence intensity of QDs was highly dependent to unmethylated and methylated DNA. Specific site of CpG islands of Adenomatous polyposis coli (APC), a well-studied tumor suppressor gene, was used as the detection target. Under optimum conditions, upon the addition of unmethylated dsDNA, the fluorescence intensity increased in linear range from 1.0?×?10??10 to 1.0?×?10??6M with detection limit of 6.2?×?10??11 M and on the other hand, the intensity of QDs showed no changes with addition of methylated dsDNA. We also demonstrated that the unmethylated and methylated DNA and QDs complexes showed different mobility in electrophoresis assay. This easy and reliable method could distinguish between methylated and unmethylated DNA sequences.  相似文献   
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In this short work, by combining the total cell evolution curve and the two-compartment model, the evolution of one of the subpopulations is simulated while the system interacts with a proliferating regulatory factor.  相似文献   
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In classical topology it is proved, nonconstructively, that for a topological space X, every bounded Riesz map ϕ in C(X) is of the form for a point xX. In this paper our main objective is to give the pointfree version of this result. In fact, we constructively represent each real Riesz map on a compact frame M by prime elements. Received March 23, 2004; accepted in final form May 14, 2005.  相似文献   
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There are many results proved using the Axiom of Choice. Using point-free topology, we can prove some of these results without using this axiom. B. Banaschewski in [Pointfree Topology and the Spectra of f-rings, Ordered algebraic structures (Curacoa, 1995), Kluwer, Dordrecht, 123–148], studying the spectra of f-rings, describes the point-free version of the classical Gelfand duality without using the Axiom of Choice In this paper, referring to [Ebrahimi, M. M., Karimi Feizabadi, A. and Mahmoudi, M.: Pointfree Spectra of Riesz Space, Appl. Categ. Struct. 12 (2004), 397–409; Ebrahimi, M. M. and Karimi Feizabadi, A.: Pointfree Spectra of ℓ-Modules, To appear in J. Pure Appl. Algebra], we describe a point-free version of the classical Kakutani duality. For this, using one of the spectra given in [Ebrahimi, M. M., Karimi Feizabadi, A. and Mahmoudi, M.: Pointfree Spectra of Riesz Space, Appl. Categ. Struct. 12 (2004), 397–409; Ebrahimi, M. M. and Karimi Feizabadi, A.: Pointfree Spectra of l-Modules, To appear in J. Pure Appl. Algebra], we find an adjunction between the category of compact completely regular frames with frame maps and the category of Archimedean bounded Riesz spaces with continuous Riesz maps.  相似文献   
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In classical topology, it is proved that for a topological space X, every bounded Riesz map \(\varphi :C (X) \rightarrow {\mathbb {R}}\) is of the from \({\hat{x}}\) for a point \(x\in X\). In this paper, our main purpose is to prove a version of this result by lattice-valued maps. A ring representation of the from \(A\rightarrow {\mathbb {R}}\) is constructed. This representation is denoted by \(\widetilde{p_c}\) that is an onto f-ring homomorphism for every \(p\in \Sigma L\), where its index c, denotes a cozero lattice-valued map. Also, it is shown that for every Riesz map \(\phi :A\rightarrow {\mathbb {R}} \) and \(c\in F(A, L)\) with specific properties, there exists \(p\in \Sigma L\) such that \(\phi =\phi (1)\widetilde{p_c}\).  相似文献   
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Russian Journal of Organic Chemistry - Four pyranopyrimidinedione derivatives were prepared through a one-pot pseudo-three-component acetic acid-catalyzed reaction of 6-amino-1,3-dimethyluracil...  相似文献   
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The partial oxidation of methane to C2 hydrocarbons was investigated experimentally in a dielectric-barrier discharge (DBD) reactor. The effects of reactor wall temperature, input gas flow rate and volumetric ratio of methane to oxygen over methane conversion and C2 production were investigated. The highest C2 selectivity of about 50% was achieved at 1.8% methane conversion. Finally the model equations were used to correlate methane conversion and ethylene selectivity with the system variable within the studied range of them. The correlation equation shows the sole effects and interaction effects of system variables on methane conversion and ethylene selectivity.  相似文献   
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