Rotaxane‐Like Structures Threaded through the Pores of Hollow Porous Nanocapusles

Nanocapsules with molecules threaded through the porous shells may lead to advanced cell‐mimicking functional devices. Herein, we show the feasibility of synthesizing such hybrid nanostructures by using vesicle‐templated polymer nanocapsules with controlled nanopores. Ship‐in‐a‐bottle assembly inside a nanocapsule created an internal unit. An external unit was then connected to an entrapped internal unit through pre‐attached linker threaded through a nanopore in the shell of the nanocapsule. Both internal and external units are larger than the pore size and cannot cross the shell, producing a rotaxane‐like structure. Successful synthesis was achieved with fairly short linkers (six and ten carbon atoms in a chain), creating an opportunity for facile synthesis of functional devices capable of cross‐shell communication.     

A phase I, randomized study of combined IL-2 and therapeutic immunisation with antiretroviral therapy

Background  

Fully functional HIV-1-specific CD8 and CD4 effector T-cell responses are vital to the containment of viral activity and disease progression. These responses are lacking in HIV-1-infected patients with progressive disease. We attempted to augment fully functional HIV-1-specific CD8 and CD4 effector T-cell responses in patients with advanced chronic HIV-1 infection.     

Synthesis, characterization, and controlled aggregation of biotemplated polystyrene nanodisks

Cross-linked polystyrene nanodisks were prepared by controlled polymerization of styrene and divinylbenzene in the interior of bicelles, discoidal lipid aggregates. Aggregation behavior of polymer nanodisks was studied in water, organic solvents, and solid phase. Nanodisks form stable dispersions in aqueous solutions of surfactants, such as sodium dodecyl sulfate (SDS). Varying SDS/nanodisk ratio allowed us to control the size of nanodisk aggregates. Nanodisks are readily solubilized in nonpolar organic solvents, such as toluene and carbon tetrachloride, to yield stable monodisperse suspensions. These findings open opportunities for creating nanodisk-based nanocomposite materials. Stable nanodisk suspension in toluene enabled small angle neutron scattering (SANS) measurements. SANS data confirmed the nanodisk diameter and allowed accurate measurement of nanodisk thickness (19.5 ± 1.0 Å). In solid phase, nanodisks aggregate in sub-micron platelets.     

Synergistic co-entrapment and triggered release in hollow nanocapsules with uniform nanopores

We describe a new co-entrapment and release motif based on the combination of noncovalent and steric interactions in materials with well-defined nanopores. Individual components enter hollow nanocapsules through nanopores in the capsule shell. Their complex, larger than the pore size, remains entrapped. The dissociation of the complex upon external stimulus releases entrapped components. Reversible formation of complexes between diaza-18-crown-6 and metal ions was used to demonstrate the feasibility of new approach to co-entrapment and triggered release.     

Ship-in-a-bottle entrapment of molecules in porous nanocapsules

Size-selective pores in the shells of hollow polymer nanocapsules enable combined assembly and entrapment of molecules. Small building blocks enter the capsule through the pores. The assembled molecules, which are larger than the pores, remain entrapped in the nanocapsules. Porous nanometre-thin walls permit unhindered functionalization of entrapped molecules.     

Modeling of the adsorption deformation of microporous adsorbents interacting with gases and vapors

A problem of modeling the adsorption deformation is examined. A model describing the elastic adsorption deformation of microporous adsorbents is suggested. Results of modeling of the CO ₂ — AUK microporous carbon adsorbent system and their comparison with the available experimental data are presented for pressures and temperatures changing in wide ranges. __________ Translated from Izvestiya Vysshikh Uchebnykh Zavedenii, Fizika, No. 11, pp. 26–32, November, 2005.     

Synthesis of new organosilicon and organogermanium derivatives of diallylisocyanurate and cyanuric acid

Conclusion The reactions of the silver, cesium or rubidium salts of diallylisocyanurate and of trimethylsilyldiallylisocyanurate with pentamethylchlorodisilane, 1,2-dichlorotetramethyldisilane, 1,3-dichlorotetramethyldisiloxane and -(trialkylgermyl)propionyl chlorides leads to the corresponding organosilicon and organogermanium triazine derivatives. The reaction of pentamethylchlorodisilane with the trisilver salt of cyanuric acid or tris(trimethyl-silyl) cyanurate leads to the formation of tris(pentamethyldisilanyl)cyanurate.Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 4, pp. 941–943, April, 1987.     

A study of the physicomechanical properties of carbon fibers at high temperatures

Conclusions 1. Carbon fibers, similar to graphite materials, are heat-resistant and do not Iose their short-term tensile strength in the temperature range studied — 20 to 2000°C.2. Young's modulus of carbon fibers hardly changes in the temperature range 20 to 1200°C, but a significant decrease is observed upon a further increase in temperature.Translated from Mekhanika Polimerov, No. 4, pp. 626–630, July–August, 1977.