Observation and analysis ofE mesons in\bar p p annihilation at rest in H2 gas

Antiproton-proton annihilation at rest in a gaseous H₂ target at NTP into the final state π⁺ π^? K ^± π^? (K ⁰) with an undetectedK ⁰ or \(\bar K^0 \) has been investigated. We observe theE(1420) resonance in the invariant mass spectrum (K ⁰)_miss K ^± π^? with massM _E =1413±8 MeV/c² and widthГ ^E =62 ± 16MeV/c² and find evidence for the production of thef ₁(1285). The absolute branching ratio of \(\bar p\) p → π⁺ π^? E ⁰,E ⁰ →K ₀ ^L K ^± π ^? at (61±6)%P wave annihilation is (3.0±0.9)·10^?4 of all annihilations. The observed suppression of theE production fromP wave with respect to theS wave together with some simple selection rules suggest that the quantum numbers of theE(1420) areJ ^pc=0^?+ and not I⁺⁺.     

Effect of Pr-Ca substitution on the transport and magnetic behavior of LaMnO3 perovskite

The effect of simultaneous substitution of a fluctuating cation and a divalent cation in LaMnO₃ perovskite modifies the properties of the material to exhibit large valence colossal magnetoresistance (CMR) effect. A good example of these properties is (La_1−2x Pr _x Ca _x )MnO₃ (LPCMO) type CMR material. In this communication it is reported that, with the increase in x (for x=0.1, 0.15, 0.2), the T _c varies between 100 and 120 K with improvisation in metal-insulator transition. Interestingly, resistance increases with x from few hundred ohms to few kilo ohms with corresponding decrease in the unit cell volume. The results of the studies using X-ray diffraction (XRD), electrical resistivity, magnetoresistance and ac susceptibility measurements on LPCMO samples for understanding the structural, transport and magnetic properties are discussed in detail.     

X-rays from antiprotonic helium in helium gas

X-ray transitions to the 4F, 3D, and 2P atomic levels of p?He have been observed with antiprotons stopped in He gas at 4 and 1.1 atm NT. The population by radiative transitions of the 3D level in gas Y_M(4atm) = (28±14)% and Y_M(1.1 atm) = (43±22)% exceeds by more than one order of magnitude that measured in liquid He. The annihilation width of the 3D level Γ^a_3D = 2.8±1.0 × 10^?3eV is determined from the ratio between the numbers of X-rays feeding and depopulating the 3D level. The strong-interaction shift of the 2P level ε(2P) = ?14±6 eV is obtained by inputting the $\text{p}\text{He}$ experimental X-ray yields into a cascade calculation, the results of which are in good agreement with well-established data from muonic, pionic, and kaonic helium.     

Pion production from deuterium bombarded with polarized protons of 277 and 500 MeV

Analyzing power measurements of the $\text{p}\text{→ tτ}{}^{\mathrm{+}}$ reaction are reported at incident proton energies of 277 and 500 MeV. The 277 MeV results span the angular range from 70° to 130° in the centre of mass while the two 500 MeV measurements at large angles were taken as a check of published results. With the angular distribution of the analyzing power at 277 MeV now known, it is possible to show that the energy dependence of the analyzing power exhibits characteristics closely resembling the shape and magnitude of the analyzing power distribution observed for 1p shell nuclei of similar excitation energies.     

A miniaturized glucocorticoid receptor translocation assay using enzymatic fragment complementation evaluated with qHTS

Nuclear translocation is an important step in glucocorticoid receptor (GR) signaling and assays that measure this process allow the identification of nuclear receptor ligands independent of subsequent functional effects. To facilitate the identification of GR-translocation agonists, an enzyme fragment complementation (EFC) cell-based assay was scaled to a 1536-well plate format to evaluate 9,920 compounds using a quantitative high throughput screening (qHTS) strategy where compounds are assayed at multiple concentrations. In contrast to conventional assays of nuclear translocation the qHTS assay described here was enabled on a standard luminescence microplate reader precluding the requirement for imaging methods. The assay uses beta-galactosidase alpha complementation to indirectly detect GR-translocation in CHO-K1 cells. 1536-well assay miniaturization included the elimination of a media aspiration step, and the optimized assay displayed a Z' of 0.55. qHTS yielded EC(50) values for all 9,920 compounds and allowed us to retrospectively examine the dataset as a single concentration-based screen to estimate the number of false positives and negatives at typical activity thresholds. For example, at a 9 microM screening concentration, the assay showed an accuracy that is comparable to typical cell-based assays as judged by the occurrence of false positives that we determined to be 1.3% or 0.3%, for a 3sigma or 6sigma threshold, respectively. This corresponds to a confirmation rate of approximately 30% or approximately 50%, respectively. The assay was consistent with glucocorticoid pharmacology as scaffolds with close similarity to dexamethasone were identified as active, while, for example, steroids that act as ligands to other nuclear receptors such as the estrogen receptor were found to be inactive.     

First observation of K X-rays from pp atoms

K and L series X-rays have been observed from p$\text{p}$ atoms formed in hydrogen gas at NTP in association with annihilations into neutral particles. The total K X-ray yield is (6.5 ± 3.2) × 10^?3 per stopped antiproton. A model-dependent fit of the K X-ray spectrum gives a K_α energy of 8.9±0.3 keV, corresponding to a strong interaction shift of (?0.5±0.3) keV.     

Antiproton-proton annihilation at rest in H2 gas into π+ π− π0

Zeitschrift für Physik C Particles and Fields - Annihilation of antiprotonic hydrogen atoms into π+ π? π0 is studied by stopping antiprotons from LEAR in hydrogen gas. Two...