Synthesis of a disaccharide of phenolic glycolipid from Mycobacterium leprae (PGL-I) and its conjugates with bovine serum albumin

Russian Chemical Bulletin - Terminal disaccharide fragment of phenolic glycolipid from Mycobacterium leprae (PGL-I) was synthesized as a glycoside with 4-(2-aminoethoxy)phenyl aglycon. The obtained...     

Synthesis and some properties of gem-dichlorocyclopropane carboxaldehyde acetals and cyclopropane carboxaldehyde acetals

α,β-Unsaturated aldehyde acetals add :CCl₂ (obtained in accordance with Makosza procedure) to form gem-dichlorocyclopropanecarboxaldehyde acetals (1) in high yields when the ratio of reactants is no less than 1:4. The addition of :CCl₂ to polyunsaturated aldehyde acetals in the above conditions proceeds regioselectively at double bonds enriched by electrons. Compounds 1 are reduced by sodium in liquid ammonia to give cyclopropanecarboxaldehyde acetals (2). Both 1 and 2 are hydrolized by dilute H₃P0₄ to the corresponding aldehydes and are added to vinyl ethers in the presence of BF₃·Et₂O to produce only 1:1 adducts which are hydrolyzed by a mixture of AcOH-AcONa-H₂O to give β-formylcyclopropanes which were previously unknown.     

A study of deuterium exchange in adamantane carboxylic acids and alcohols under electron impact

The mass spectra of 1-adamantyl substituted carboxylic acids and alcohols with and without deuterated hydroxyl groups were studied. Deuterium exchange between functional group and adamantane nucleus was observed and a possible explantation of the phenomenon is given.     

Vilsmeier formylation of 2-methyl-3 -carbethoxy-5-methoxy- and 2-methyl-5-methoxyindoles

The corresponding 6- and 3-formyl derivatives were obtained by formylation of 2-methyl-3-carbethoxy-5-methoxy- and 2-methyl-5-methoxyindole derivatives.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 3, pp. 339–341, March, 1971.     

Mass spectrometry of kaurene derivatives—I. The mass spectra of some (−)-kauran-16-ols

The mass spectra of nine compounds belonging to the group of (?)-kauran-16-ols are reported. These compounds differ either by stereochemistry at C₁₆ (I, II) or by the nature of the substituent at C₄ (III to VIII). In all cases the most characteristic ions correspond to a process in which ring D is split off and lost as a C₃H₆O fragment. The nature of the substituent R₁ at C₄ can be deduced from such typical ions as [M ? R₁]+ or [M ? R₁ ? H₂O]+. Kauranols epimeric at C₁₆ show little difference in their mass spectra; the assignment of configuration at this centre may be reliable only when the spectra of both epimers are compared.