全文获取类型
收费全文 | 1109篇 |
免费 | 47篇 |
国内免费 | 22篇 |
专业分类
化学 | 737篇 |
晶体学 | 13篇 |
力学 | 19篇 |
综合类 | 1篇 |
数学 | 160篇 |
物理学 | 248篇 |
出版年
2023年 | 6篇 |
2022年 | 9篇 |
2021年 | 10篇 |
2020年 | 25篇 |
2019年 | 12篇 |
2018年 | 17篇 |
2017年 | 17篇 |
2016年 | 26篇 |
2015年 | 20篇 |
2014年 | 29篇 |
2013年 | 63篇 |
2012年 | 61篇 |
2011年 | 63篇 |
2010年 | 38篇 |
2009年 | 33篇 |
2008年 | 50篇 |
2007年 | 67篇 |
2006年 | 57篇 |
2005年 | 41篇 |
2004年 | 59篇 |
2003年 | 53篇 |
2002年 | 50篇 |
2001年 | 28篇 |
2000年 | 23篇 |
1999年 | 11篇 |
1998年 | 15篇 |
1997年 | 14篇 |
1996年 | 24篇 |
1995年 | 13篇 |
1994年 | 15篇 |
1993年 | 13篇 |
1992年 | 16篇 |
1991年 | 6篇 |
1990年 | 10篇 |
1989年 | 13篇 |
1988年 | 11篇 |
1987年 | 12篇 |
1985年 | 8篇 |
1984年 | 8篇 |
1983年 | 7篇 |
1981年 | 6篇 |
1980年 | 8篇 |
1979年 | 7篇 |
1977年 | 6篇 |
1976年 | 7篇 |
1975年 | 7篇 |
1974年 | 10篇 |
1973年 | 10篇 |
1972年 | 6篇 |
1971年 | 6篇 |
排序方式: 共有1178条查询结果,搜索用时 31 毫秒
1.
Lee Stephen; Harrison Martin C.; Robinson Carol L. 《Teaching Mathematics and its Applications》2007,26(3):111-118
In the past 6 years changes have occurred in GCE A-levels. Inparticular, there have been several major changes in A-levelMathematics courses. As engineering students are usually requiredto have studied A-level Mathematics, or its equivalent, thesechanges have had an effect on their prior mathematical knowledge.Moreover, engineering students traditionally obtained a goodgrounding in mechanics as part of their A-level Mathematicsqualification. However, mechanics, which was once included inthe core syllabus, is now optional. This article investigatesthe current availability and uptake of mechanics modules withinA-level Mathematics courses in schools. Comparisons are drawnbetween these results and results of a survey of schools in2004 and surveys of first year engineering students conductedin 2004 and 2005. It is found that there is a decline in theavailability of mechanics modules and the uptake of more thanone mechanics module has also decreased. The implications ofthese findings for engineering educators are discussed. 相似文献
2.
The enthalpies of formation of simple nonmetal or metalloid oxyanions in aqueous solution are discussed. Archival values are cited and estimates are made. Trends prove evasive. 相似文献
3.
4.
本证明了当(a,b)不属于{(1,8),(2,4),(3,6),(4,4),(2s^2-s,2s^2 s))时,L^m(Ka,b)以谱为特征,其中a≤b,s≥2. 相似文献
5.
Isabel Cristina S. F. Jardim Kenneth E. Collins Carol H. Collins 《Microchemical Journal》2004,77(2):191-198
Polysiloxanes immobilized onto the surfaces of porous silica particles have proven to be good stationary phases for the separation of multiresidues of pesticides and their metabolic/degradation products by reversed-phase high-performance liquid chromatography (RP-HPLC). Similar materials have proven effective for pre-concentration and clean-up procedures using solid phase extraction. The present paper describes the preparation and some applications of several of these packing materials. 相似文献
6.
Kate B. Poiesz Carol L. Grundner Nancy L. Redman-Furey 《Journal of Thermal Analysis and Calorimetry》2006,85(1):79-86
Characterization of the solid-state form (hydrate
or polymorph) of a pharmaceutical active is a key scientific and regulatory
requirement during development of and prior to seeking approval for marketing
of the drug product. A variety of analytical methods are available to perform
this task. By nature of the fundamental information it provides, TG-DTA offers
advantages over other methods in regards to monitoring and quantitation of
hydration state changes. In a single experiment with only a few milligrams
of sample, TG-DTA perceives minor changes in phase, quantitates total water
content and percent conversion, and illustrates hydrate type. All of this
is accomplished without the necessity of generating time-consuming standard
curves representing the differing ratios of hydrated to anhydrous forms. This
study describes the use of TG-DTA to monitor and quantitate humidity induced
solid–solid phase conversion of nitrofurantoin and risedronate. Percent
conversion was qualitatively observed by both TG and DTA signals and quantitated
by the TG. 相似文献
7.
Tobacco protein separation by aqueous two-phase extraction 总被引:13,自引:0,他引:13
Tobacco has long been considered as a host to produce large quantity of high-valued recombinant proteins. However, dealing with large quantities of biomass is a challenge for downstream processing. Aqueous two-phase extraction (ATPE) has been widely used in purifying proteins from various sources. It is a protein-friendly process and can be scaled up easily. In this paper, ATPE was studied for its applicability to recombinant protein purification from tobacco with egg white lysozyme as the model protein. Separate experiments with poly(ethylene glycol) (PEG)-salt-tobacco extract and PEG-salt-lysozyme were carried out to determine the partition behavior of tobacco protein and lysozyme, respectively. Two-level fractional factorial designs were used to study the effects of factors such as, PEG molecular mass, PEG concentration, the concentration of phase forming salt, sodium chloride concentration and pH, on protein partitioning. The results showed that, among the studied systems, PEG-sodium sulfate system was most suitable for lysozyme purification. Detailed experiments were conducted by spiking lysozyme into the tobacco extract. The conditions with highest selectivity of lysozyme over native tobacco protein were determined using a response surface design. The purification factor was further improved by decreasing the phase ratio along the tie line corresponding to the phase compositions with the highest selectivity. Under selected conditions the lysozyme yield was predicted to be 87% with a purification factor of 4 and concentration factor of 14. From this study, ATPE was shown to be suitable for initial protein recovery and partial purification from transgenic tobacco. 相似文献
8.
W 7-agarose是常用的细胞外CaM功能的拮抗剂,本实验采用荧光光谱法研究了水溶液中钙调素拮抗剂W 7-agarose与植物胞外钙调素的相互结合反应。W 7-agarose是一种将W 7-共价连接到颗粒型agarose(琼脂糖)的粒子。W 7-agarose颗粒较大且容易沉淀,静置5m in后,溶液中的荧光强度完全由游离的CaM产生。在溶液中加入W 7-agarose后,溶液中一部分CaM与其结合后沉降至荧光比色皿底部,导致溶液中CaM的荧光强度下降。由此可以确定溶液中游离CaM的浓度。根据公式lg{[Q]t(F0-F)/F0}=nlg{[Q]tF/F0} lgnK[B]t,从而计算出配位体系的结合常数和配比。研究表明:二者以摩尔比1∶1结合,其平衡常数为4.9×105。由此进一步计算了W 7-agarose对胞外钙调素的拮抗率,在拮抗剂W 7-agarose浓度达到15~20μmol/L时,拮抗率可达到90%以上,与文献报道的生物学体内实验结果一致,从分子水平上解释了W 7-agarose与CaM的结合作用。 相似文献
9.
María Beatriz de la Calle Guntiñas Michiel Ceulemans Claudia Witte Ryszard Łobiński Freddy C. Adams 《Mikrochimica acta》1995,120(1-4):73-82
A method is presented for the selective determination of the volatile selenium species dimethylselenide and dimethyldiselenide, using a commercially available purge-and-trap injection system coupled to capillary gas chromatography-microwave induced plasma-atomic emission spectrometry. The efficiency of the purging step was evaluated and the parameters affecting the purge and trap processes were optimized. The method was applied to the determination of volatile selenium compounds in lake water. Relative detection limits of 2ng/l for dimethylselenide and dimethyldiselenide, corresponding to an absolute detection limit of 10 pg, were achieved. 相似文献
10.
Dietmar Seyferth Don P. Duncan Carol K. Haas 《Journal of organometallic chemistry》1979,164(3):305-316
The reaction of 1,1-dimethyl-trans-2,3,-bis(2′,2′-dimethylcyclopropylidene)-1-silirane with S8 gives a mixture of four isomeric products derived from incorporation of one sulfur atom and a cyclopropylcarbinyl-to-butenyl type rearrangement. This silirane reacts with t-butyl mercaptan to give a product of mercaptan addition in which a cyclopropylcarbinyl-to-butenyl rearrangement also has occurred. Hexamethylsilirane reacts with S8 to give 1,1,4,4,5,5-hexamethyl-2,3-dithia-1-silacyclopentane in high yield. These reactions are discussed in terms of free radical mechanisms. 相似文献