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The interactions of ciprofloxacin (HCipro) with transition metals have been investigated. Two types of complexes, [M(Cipro)(OAc)(H2O)2] · 3H2O (M = MnII, CoII, CuII or CdII) and [M(Cipro)(OAc)] · 6H2O (M = NiII or ZnII), were obtained and characterized by physicochemical and spectroscopic methods. The i.r. spectra of the complexes suggest that the ciprofloxacin behaves as a monoanionic bidentate ligand. In vitro antibacterial activities of the HCipro and the complexes were tested. 相似文献
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