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The present study is concerned with the determination of the optimal shape for a package containing multiple heating elements.
The optimization tool has been developed based on the inverse heat transfer (IHT) approach, incorporating a direct problem
solver, a numerical grid generator, a direct-differentiation sensitivity analyzer, and the conjugate gradient method. Shape
design that leads to a specified outer surface temperature distribution is predicted by the approach. In this study, the effects
of internal heat generation on optimal shapes of the packagings have also been evaluated. Several practical cases with various
imbedded heating elements and thermal conditions are studied. Results show that the approach provides an efficient computer-aided
design scheme for the shape profile determination. 相似文献
2.
2-Pyridine sulfenyl chloride (PS-Cl) is a useful reagent for simultaneously deprotecting and activating the mercapto-group of cysteine and of cysteine-peptides preliminary to disufide-bond formation. The S-protecting groups that are amenable to this reaction include trityl, diphenylmethyl, acetamidomethyl, t-butyl, and t-butylsulfenyl. 相似文献
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Structures and Bioactivities of Steroidal Saponins Isolated from the Genera Dracaena and Sansevieria
Zaw Min Thu Sann Myint Oo Thinn Myat Nwe Hnin Thanda Aung Chabaco Armijos Faiq H. S. Hussain Giovanni Vidari 《Molecules (Basel, Switzerland)》2021,26(7)
The species Dracaena and Sansevieria, that are well-known for different uses in traditional medicines and as indoor ornamental plants with air purifying property, are rich sources of bioactive secondary metabolites. In fact, a wide variety of phytochemical constituents have been isolated so far from about seventeen species. This paper has reviewed the literature of about 180 steroidal saponins, isolated from Dracaena and Sansevieria species, as a basis for further studies. Saponins are among the most characteristic metabolites isolated from the two genera. They show a great variety in structural motifs and a wide range of biological activities, including anti-inflammatory, anti-microbial, anti-proliferative effects and, in most case, remarkable cytotoxic properties. 相似文献
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Othmar Leukart Mario Caviezel Alex Eberle Emanuel Escher Aung Tun-Kyi Robert Schwyzer 《Helvetica chimica acta》1976,59(6):2181-2183
The chemical synthesis of L -propargylglycine (L -Pra) and of various derivatives is described. The new amino acid is a starting material for carboranylalanine (Car) and for tritiated norleucine. 相似文献
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Othmar Leukart Mario Caviezel Alex Eberle Emanuel Escher Aung Tun-Kyi Robert Schwyzer 《Helvetica chimica acta》1976,59(6):2184-2187
The synthesis of a new, boron-containing analogue of phenylalanine is described. Carboranylalanine (Car) carries a 1,2-carborane cage in place of the benzene ring of phenylalanine. It is obtained by the reaction of derivatives of propargylglycine with decaborane. Possibilities of practical application derive from the facile neutron activation of boron nuclei with mass number 10. 相似文献
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Rudolf Wunderlin Panagiota Minakakis Aung Tun-Kyi Shub Dev Sharma Robert Schwyzer 《Helvetica chimica acta》1985,68(1):1-11
Chemical synthesis and biological activities of a new α-melanotropin derivative are described. Nα-(5-Bromovaleryl)-Nα-deacetyl-α-melanotropin contains the 5-bromopentanoyl group as a chemical ‘handle’ in place of the acetyl group of the natural hormone. The synthesis involved a new protected intermediate which allowed the selective deprotection of either the Nα or Nα amino group. The title compound reacted with sodium thiosulfate to give Nα-deacetyl-Nα-(5-(sulfothio)valeryl)-α-melanotropin, a key intermediate for the preparation of tobaccomosaic virus/α-melanotropin disulfide conjugates. As a basis for the study of the conjugates, biological activities of the title compound on Cloudman S-91 mouse melanoma cell cultures (tyrosinase stimulation, binding, and cyclic AMP accumulation) were determined. They proved to be quite similar to the corresponding α-melanotropin activities. Differences in bindings may be explained by stronger hydrophobic interaction of the new derivative with the lipid phase of the target cell membranes. 相似文献
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It was found by the Michelson interferometric method that an absorption of 10.6 μm laser pulse generates an acoustic wave transverse to the direction of laser propagation in SF6. 相似文献