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This study assessed the extent to which second-language learners are sensitive to phonetic information contained in visual cues when identifying a non-native phonemic contrast. In experiment 1, Spanish and Japanese learners of English were tested on their perception of a labial/ labiodental consonant contrast in audio (A), visual (V), and audio-visual (AV) modalities. Spanish students showed better performance overall, and much greater sensitivity to visual cues than Japanese students. Both learner groups achieved higher scores in the AV than in the A test condition, thus showing evidence of audio-visual benefit. Experiment 2 examined the perception of the less visually-salient /1/-/r/ contrast in Japanese and Korean learners of English. Korean learners obtained much higher scores in auditory and audio-visual conditions than in the visual condition, while Japanese learners generally performed poorly in both modalities. Neither group showed evidence of audio-visual benefit. These results show the impact of the language background of the learner and visual salience of the contrast on the use of visual cues for a non-native contrast. Significant correlations between scores in the auditory and visual conditions suggest that increasing auditory proficiency in identifying a non-native contrast is linked with an increasing proficiency in using visual cues to the contrast.  相似文献   
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Background

Caspase-3 is one of the most downstream enzymes activated in the apoptotic pathway. In caspase-3 deficient mice, loss of cochlear hair cells and spiral ganglion cells coincide closely with hearing loss. In contrast with the auditory system, details of the vestibular phenotype have not been characterized. Here we report the vestibular phenotype and inner ear anatomy in the caspase-3 deficient (Casp3 -/- ) mouse strain.

Results

Average ABR thresholds of Casp3 -/- mice were significantly elevated (P < 0.05) compared to Casp3 +/- mice and Casp3 +/+ mice at 3 months of age. In DPOAE testing, distortion product 2F1-F2 was significantly decreased (P < 0.05) in Casp3 -/- mice, whereas Casp3 +/- and Casp3 +/+ mice showed normal and comparable values to each other. Casp3 -/- mice were hyperactive and exhibited circling behavior when excited. In lateral canal VOR testing, Casp3 -/- mice had minimal response to any of the stimuli tested, whereas Casp3 +/- mice had an intermediate response compared to Casp3 +/+ mice. Inner ear anatomical and histological analysis revealed gross hypomorphism of the vestibular organs, in which the main site was the anterior semicircular canal. Hair cell numbers in the anterior- and lateral crista, and utricle were significantly smaller in Casp3 -/- mice whereas the Casp3 +/- and Casp3 +/+ mice had normal hair cell numbers.

Conclusions

These results indicate that caspase-3 is essential for correct functioning of the cochlea as well as normal development and function of the vestibule.  相似文献   
4.
The hard X‐ray beamline BL8 at the superconducting asymmetric wiggler at the 1.5 GeV Dortmund Electron Accelerator DELTA is described. This beamline is dedicated to X‐ray studies in the spectral range from ~1 keV to ~25 keV photon energy. The monochromator as well as the other optical components of the beamline are optimized accordingly. The endstation comprises a six‐axis diffractometer that is capable of carrying heavy loads related to non‐ambient sample environments such as, for example, ultrahigh‐vacuum systems, high‐pressure cells or liquid‐helium cryostats. X‐ray absorption spectra from several reference compounds illustrate the performance. Besides transmission measurements, fluorescence detection for dilute sample systems as well as surface‐sensitive reflection‐mode experiments have been performed. The results show that high‐quality EXAFS data can be obtained in the quick‐scanning EXAFS mode within a few seconds of acquisition time, enabling time‐resolved in situ experiments using standard beamline equipment that is permanently available. The performance of the new beamline, especially in terms of the photon flux and energy resolution, is competitive with other insertion‐device beamlines worldwide, and several sophisticated experiments including surface‐sensitive EXAFS experiments are feasible.  相似文献   
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We study pattern formation during tensile deformation of confined viscoelastic layers. The use of a model system [poly(dimethylsiloxane) with different degrees of cross-linking] allows us to go continuously from a viscous liquid to an elastic solid. We observe two distinct regimes of fingering instabilities: a regime called "elastic" with interfacial crack propagation, where the fingering wavelength scales only with the film thickness, and a bulk regime called "viscoelastic," where the fingering instability shows a Saffman-Taylor-like behavior. We find good quantitative agreement with theory in both cases and present a reduced parameter describing the transition between the two regimes and allowing us to predict the observed patterns over the whole range of viscoelastic properties.  相似文献   
7.
The mechanical properties of composite membranes obtained by self-assembly of actin filaments with giant fluid vesicles are studied by micromanipulation with optical tweezers. These complexes exhibit typical mechanical features of a solid shell, including a finite in-plane shear elastic modulus ( approximately 10(-6) N/m). A buckling instability is observed when a localized force of the order of 0.5 pN is applied perpendicular to the membrane plane. Although predicted for polymerized vesicles, this is the first evidence of such an instability.  相似文献   
8.
Exchange splitting and dynamics of image-potential states in front of a 3 monolayer iron film on Cu(100) have been studied with time-, energy-, and spin-resolved bichromatic two-photon photoemission. For the first image-potential state n=1 we observe an exchange splitting of 56 +/- 10 meV and spin-dependent lifetimes of 16 +/- 2 fs for majority-spin and of 11 +/- 2 fs for minority-spin electrons, respectively. The time-resolved studies of both the population and the linewidth of image-potential states manifest that at the magnetic surface not only inelastic but also quasielastic scattering processes are spin dependent.  相似文献   
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A high‐repetition‐rate pump–probe experiment is presented, based on the asynchronous sampling approach. The low‐α mode at the synchrotron ANKA can be used for a time resolution down to the picosecond limit for the time‐domain sampling of the coherent THz emission as well as for hard X‐ray pump–probe experiments, which probe structural dynamics in the condensed phase. It is shown that a synchronization of better than 1 ps is achieved, and examples of phonon dynamics of semiconductors are presented.  相似文献   
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