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1.
Manuel Cano Beatriz Palenzuela J. Luis Ávila Rafael Rodríguez‐Amaro 《Electroanalysis》2007,19(9):973-977
A PVC/TTF‐TCNQ composite electrode has been employed as detector in a flow injection system. The proposed method allows the simultaneous detection of ascorbic acid (AA) and uric acid (UA) in mixtures by using a FIA system in a simple manner, without pre‐treatment or modified electrode. This method is based on the amperometric determination of (a) ascorbic acid at 0.15 V and (b) both analytes at 0.35 V, being the response linear in the range 1×10?2–4×10?4 M for both analytes with detection limits (S/N=3) of 1.2×10?4 M and 8.1×10?5 M for AA and UA, respectively. 相似文献
2.
Fernando Bento Cunha Karina Torres Pomini Ana Maria de Guzzi Plepis Virgínia da Conceio Amaro Martins Eduardo Gomes Machado Renato de Moraes Marcelo de Azevedo e Souza Munhoz Michela Vanessa Ribeiro Machado Marco Antonio Hungaro Duarte Murilo Priori Alcalde Daniela Vieira Buchaim Rogrio Leone Buchaim Victor Augusto Ramos Fernandes Eliana de Souza Bastos Mazuqueli Pereira Andr Antonio Pelegrine Marcelo Rodrigues da Cunha 《Molecules (Basel, Switzerland)》2021,26(6)
Autologous bone grafts, used mainly in extensive bone loss, are considered the gold standard treatment in regenerative medicine, but still have limitations mainly in relation to the amount of bone available, donor area, morbidity and creation of additional surgical area. This fact encourages tissue engineering in relation to the need to develop new biomaterials, from sources other than the individual himself. Therefore, the present study aimed to investigate the effects of an elastin and collagen matrix on the bone repair process in critical size defects in rat calvaria. The animals (Wistar rats, n = 30) were submitted to a surgical procedure to create the bone defect and were divided into three groups: Control Group (CG, n = 10), defects filled with blood clot; E24/37 Group (E24/37, n = 10), defects filled with bovine elastin matrix hydrolyzed for 24 h at 37 °C and C24/25 Group (C24/25, n = 10), defects filled with porcine collagen matrix hydrolyzed for 24 h at 25 °C. Macroscopic and radiographic analyses demonstrated the absence of inflammatory signs and infection. Microtomographical 2D and 3D images showed centripetal bone growth and restricted margins of the bone defect. Histologically, the images confirmed the pattern of bone deposition at the margins of the remaining bone and without complete closure by bone tissue. In the morphometric analysis, the groups E24/37 and C24/25 (13.68 ± 1.44; 53.20 ± 4.47, respectively) showed statistically significant differences in relation to the CG (5.86 ± 2.87). It was concluded that the matrices used as scaffolds are biocompatible and increase the formation of new bone in a critical size defect, with greater formation in the polymer derived from the intestinal serous layer of porcine origin (C24/25). 相似文献
3.
Parks Conor D. Gaieb Zied Chiu Michael Yang Huanwang Shao Chenghua Walters W. Patrick Jansen Johanna M. McGaughey Georgia Lewis Richard A. Bembenek Scott D. Ameriks Michael K. Mirzadegan Tara Burley Stephen K. Amaro Rommie E. Gilson Michael K. 《Journal of computer-aided molecular design》2020,34(2):99-119
Journal of Computer-Aided Molecular Design - The Drug Design Data Resource (D3R) aims to identify best practice methods for computer aided drug design through blinded ligand pose prediction and... 相似文献
4.
Data on LambdaLambda hypernuclei provide a unique method to learn details about the strangeness S = -2 sector of the baryon-baryon interaction. From the free space Bonn-Jülich potentials, determined from data on baryon-baryon scattering in the S = 0,-1 channels, we construct an interaction in the S = -2 sector to describe the experimentally known LambdaLambda hypernuclei. After including short-range (Jastrow) and RPA correlations, we find masses for these LambdaLambda hypernuclei in a reasonable agreement with data, taking into account theoretical and experimental uncertainties. Thus, we provide a natural extension, at low energies, of the Bonn-Jülich one-boson exchange potentials to the S = -2 channel. 相似文献
5.
D. Gotta F. D. Amaro D. F. Anagnostopoulos P. Bühler H. Gorke D. S. Covita H. Fuhrmann A. Gruber M. Hennebach A. Hirtl T. Ishiwatari P. Indelicato T. S. Jensen E.-O. Le Bigot V. E. Markushin J. Marton M. Nekipelov V. N. Pomerantsev V. P. Popov J. M. F. dos Santos S. Schlesser Ph. Schmid L. M. Simons Th. Strauch M. Theisen M. Trassinelli J. F. C. A. Veloso J. Zmeskal 《Hyperfine Interactions》2015,234(1-3):105-111
6.
Cycloaddition of naphthazarin and derivatives to dienols, generated thermnally from benzocyclobuenol or by irradiation of 2-methylbenzaldehyde or 2-methylacetophenone, leads to tetracyclic systems related to those present in anthracycline and tetracycline antibiotics. 相似文献
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Back Cover: GM1 Ganglioside Inhibits β‐Amyloid Oligomerization Induced by Sphingomyelin (Angew. Chem. Int. Ed. 32/2016) 下载免费PDF全文
9.
da Silva Junior IJ Sartor JP Rosa PC de Veredas V Barreto Júnior AG Santana CC 《Journal of chromatography. A》2007,1162(1):97-102
Chromatographic separation of the chiral drugs rolipram, bupivacaine and omeprazole on a tartardiamide-based stationary phase commercially named Kromasil CHI-TBB is shown in this work. The effect of temperature on the chromatographic separation of the chiral drugs using the Kromasil CHI-TBB stationary phase was determined quantitatively so as to contribute toward the design for the racemic mixtures of the named compound by using chiral columns. A decrease in the retention and selectivity factors was observed, when the column temperature increased. Van't Hoff plots provided the thermodynamic data. The variation of the thermodynamic parameters enthalpy and entropy are clearly negative meaning that the separation is enthalpy controlled. 相似文献
10.
Vladimir V. Kouznetsov Carlos M. Meléndez Gómez Juan M. Urbina González Elena E. Stashenko Ali Bahsas Juan Amaro‐Luis 《Journal of heterocyclic chemistry》2007,44(3):551-555
A study on interaction between N‐(4‐pyridinyliden)anilines 1‐4 and 2,2‐dimethoxypropane under Kametani reaction conditions was realized. According to the GC‐MS analysis of crude reaction, besides the needed 4‐methyl‐2‐(4‐pyridinyl)quinolines 5‐8 , three collateral products: secondary amines 9‐12 , 4‐(2‐methylprop‐1‐enyl)quinolines 13‐16 and 4‐(2‐methoxy‐2‐methylpropyl)quinolines 17‐20 were formed. Unexpected quinolines 13‐16 as well the desired quinolines 5‐8 were isolated and fully characterized. In contrast, a condensation of N‐benzylidenaniline 21 with 2,2‐dimethoxypropane afforded a set of different quinoline products. 相似文献