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排序方式: 共有1498条查询结果,搜索用时 31 毫秒
1.
Nonlinear Dynamics - The nonlinear modes of a non-conservative nonlinear system are sometimes referred to as damped nonlinear normal modes (dNNMs). Because of the non-conservative... 相似文献
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Functional Binding Surface of a β‐Hairpin VEGF Receptor Targeting Peptide Determined by NMR Spectroscopy in Living Cells
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Dr. Donatella Diana Anna Russomanno Dr. Lucia De Rosa Dr. Rossella Di Stasi Dr. Domenica Capasso Dr. Sonia Di Gaetano Dr. Alessandra Romanelli Dr. Luigi Russo Dr. Luca D. D'Andrea Prof. Roberto Fattorusso 《Chemistry (Weinheim an der Bergstrasse, Germany)》2015,21(1):91-95
In this study, the functional interaction of HPLW peptide with VEGFR2 (Vascular Endothelial Growth Factor Receptor 2) was determined by using fast 15N‐edited NMR spectroscopic experiments. To this aim, 15N uniformly labelled HPLW has been added to Porcine Aortic Endothelial Cells. The acquisition of isotope‐edited NMR spectroscopic experiments, including 15N relaxation measurements, allowed a precise characterization of the in‐cell HPLW epitope recognized by VEGFR2. 相似文献
4.
In this work, the NP-hard maximum clique problem on graphs is considered. Starting from basic greedy heuristics, modifications and improvements are proposed and combined in a two-phase heuristic procedure. In the first phase an improved greedy procedure is applied starting from each node of the graph; on the basis of the results of this phase a reduced subset of nodes is selected and an adaptive greedy algorithm is repeatedly started to build cliques around such nodes. In each restart the selection of nodes is biased by the maximal clique generated in the previous execution. Computational results are reported on the DIMACS benchmarks suite. Remarkably, the two-phase procedure successfully solves the difficult Brockington-Culberson instances, and is generally competitive with state-of-the-art much more complex heuristics. 相似文献
5.
Andrea Grosso Marco Locatelli Fabio Schoen 《Computational Optimization and Applications》2007,38(3):351-370
In this paper we perform a computational analysis of a population based approach for global optimization, Population Basin
Hopping (PBH), which was proven to be very efficient on very challenging global optimization problems by the authors (see
). The experimental analysis aims at understanding more deeply how the approach works and why it is successful on challenging
problems. 相似文献
6.
Giovanni Tartarini Alessandra Lena Davide Passaro Lorenzo Rosa Stefano Selleri Pier Faccin Enrico Maria Fabbri 《Optical and Quantum Electronics》2006,38(9-11):869-876
A comprehensive numerical tool has been developed for the evaluation of the performances of Radio over Fiber (RoF) links intended for wireless signal distribution.At the transmitter end an appropriate set of rate equations allows to model the optical source as a solitary laser or as an appropriately injection locked laser. The optical channel is modeled putting into account the combined effect of fiber dispersion, laser source non ideal performances (e.g. non-linear effects, frequency chirp), and quadratic detection of the receiving photodiode. The simulation model developed can be a useful tool at the design stage allowing a preliminary evaluation of the characteristics of real RoF links. 相似文献
7.
Modal logics with the binary operator Until are considered. It is shown that there exists a continuum of consistent U-logics without Kripke frames, and that each U-logic whose class of order does not have the finite frame property. 相似文献
8.
Ilaria Fratoddi Chiara Battocchio Alessandra L. Groia Maria V. Russo 《Journal of polymer science. Part A, Polymer chemistry》2007,45(15):3311-3329
The reactivity of square planar palladium(II) and platinum(II) complexes in trans or cis configuration, namely trans or cis‐[dichlorobis(tributylphosphine)platinum(II)] and trans‐[dichlorobis(tributylphosphine)palladium(II)] with 1,1′‐bis(ethynyl) 4,4′‐biphenyl, DEBP, leading to π‐conjugated organometallic oligomeric and polymeric metallaynes, was investigated by a systematic variation of the reaction conditions. The formation of polymers and oligomers with defined chain length [? M(PBu3)2 (C?C? C6H4? C6H4? C?C? )]n (n = 3–10 for the oligomers, n = 20–50 for the polymers) depends on the configuration of the precursor Pt(II) and Pd(II) complexes, the presence/absence of the catalyst CuI, and the reaction time. A series of model reactions monitored by XPS, GPC, and NMR 31P spectroscopy showed the route to modulate the chain growth. As expected, the nature of the transition metal (Pt or Pd) and the molecular weight of the polymers markedly influence the photophysical characteristics of the polymetallaynes, such as optical absorption and emission behavior. Polymetallaynes with nanostructured morphology could be obtained by a simple casting procedure of polymer solutions. © 2007 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 45: 3311–3329, 2007 相似文献
9.
Alessandra Cirla 《Tetrahedron》2004,60(18):4019-4029
The work presents a synthetic route to the CD ring of calicheamicin and in the case of neocarzinostatin an approach to a functionalised cyclopentane-1,3-diol containing the naturally occurring naphthoate and a glucosamine motif. In the case of the NCS derivative some biological activity (cytotoxicity) was observed. 相似文献
10.
We consider a planar four-vortex system with unit intensities and apply the KAM theorem for two-dimensional tori with fixed frequency. We obtain a rigorous lower bound for the stochasticity threshold of the torus with rotation number=(5—1)/2 and compare our result with numerical experiments. 相似文献