EFFECTS OF SOME Ca~(2+) BLOCKER ON RECEPTOR POTENTIALS OF CRAYFISH RETINA

One drug known to inactivate calmodulin and two others to block Ca~(2+) channels were applied to isolated superfused retinae of the crayfish Astacus leptodactylus and their influence on the receptor potentials (RP) was studied. Trifluoperazine causes an increase of the amplitude of maximum (h_(max))of RP and a prolongation of the time of half decrease (t_2). Furthermore, trifluoperazine could antagonise the effect of raised calcium concentration of superfusate, which decreases h_(max) and shortens t_2 of the RP. Iproveratril and D-600 cause a transient increase and thereafter a progressive decrease of h_(max) of the RP. There is a difference between effects of both drugs on t_2 of the RP. The mechanisms of effects of these drugs on the sensitivity of the isolated retina are discussed.     

几种钙离子阻断剂对龙虾(Astacus)光感受器电位的影响

本文首次以一种抑制钙调蛋白(Calmodulin)和两种阻断钙离子通道的药物作用于离体的龙虾视网膜,观察其对感受器电位的影响。结果表明:Trifluoperazine能使感受器电位的最大振幅h_(max)增大和下降相半衰期t_2延长。而且也能拮抗提高灌流液钙浓度而引起的h_(max)降低和t_2缩短。Iproveratril和D-600首先引起暂时性的h_(max)增大,然后逐渐下降。后两种药物对t_2的效应则有所不同。Iproveratril主要引起t_2逐渐延长;而D-600则使之缩短,并讨论了这三种药物对视网膜敏感度的作用机理。     

光电化学在有机合成中的应用

近年来，光电化学技术逐渐发展为有效的有机合成手段。光化学高效的催化性能与电化学反热力学直觉特性的结合大大简化了某些有机合成路线。本文介绍了当前与光电化学相关的部分有机反应，总结了在光电化学中广泛应用的若干染料敏化催化剂，并展望了光电化学未来的应用前景。