Study on Molecular Recognition of Crown Ethers to Aniline and Monosaccharides

1 INTRODUCTION Chemical systems can store information on supra-molecular structures in a comparative way on diffe-rent states of chemical species in a numerical way.Davis[1] reviewed non-covalent weak interaction be-tween biomimetic hosts and carbohydrates. Inouye[2]synthesized macrocyclic polypyridine and observedits molecular recognition to ribose and monosacc-harides. Furuta[3] indicated that crown ethers can ex-tract AMP. Kobayashi[4] investigated 1:1 host-guestcomplexes of crown et…     

30-冠-10对生物极性客体的分子识别和分子开关

用AM1,MNDO和PM3方法对30-冠-10与苯衍生物及其生物活性物质脱氧核糖、核糖和呋喃果糖的超分子配合物进行理论研究,得到配合物的稳定化能,结果表明,冠醚对极性客体具有识别作用,尤其对脱氧核糖的识别效果较好。用INDO／SCI方法计算超分子配合物的电子吸收光谱,计算结果表明,配合物的光谱吸收峰与主体相比发生蓝移。探讨了冠醚和间二苯甲酸配合物的分子开关的形成机理。