Synthesis,Crystal Structure and Anti-fungal/Anti-oomycete Activity of New Pyrazole-benzene Carboxamide Derivatives

Four novel pyrazole-benzene carboxamide derivatives 2 a～2 d were synthesized and characterized by NMR, HRMS spectral method and X-ray diffraction analysis, and were further conducted for screening the anti-fungal/anti-oomycete activity. Compound 2 d crystallizes as monoclinic space group P21/c with a = 42.260（4）, b = 5.3751（4）, c = 8.0129（9） ?, β = 92.958（10）°, V = 1817.7（3） ?3, Z = 4, Mr = 385.41, Dc = 1.408 Mg/m³, S = 1.087, m = 0.773 mm-1, F（000） = 808, the final R = 0.0763 and w R...