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1INTRODUCTIONThiosemicarbazidespossessingNC=Sgroupareanessentialstructurefeatureresponsibleforvariousbiocidalproperties[1~7].Moreover,theyaretheconvenientandkeyintermediatesforthesyn-thesisofheterocycliccompoundssuchas1,3,4-thiadiazoles,1,2,4-triazoleand… 相似文献
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Introduction Pyrazole and its derivatives represent one of the most active classes of compounds possessing a wide spectrum of biological activities. During the past years, considerable evidence has been accumulated to demon-strate the efficacy of pyrazole derivatives including an-tibacterial,1 antifungal,2 herbicidal,3 insecticidal4 and other biological activities.5-7 Up to now, a great variety of these kind of compounds have been synthesized, among which some commercially pesticides have been… 相似文献
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1 INTRODUCTION Pyrazole and its derivatives represent one of the most active classes of compounds possessing a wide spectrum of biological activities. During the past years considerable evidence has been accumulated to demonstrate the efficacy of pyra- … 相似文献
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Synthesis and Structure of 2-Isobutyl-6-(2'''',4''''-dichlorophenyl)imidazo[2,1-b]-1,3,4-thiadiazole 总被引:1,自引:0,他引:1
1INTRODUCTIONThethiadiazoleandimidazolecompoundsareextensivelystudiedduetotheirspectrumbioacti-vities[1~4].Amongthem,theimidazo[2,1-b]-1,3,4-thiadiazolederivativesarepharmaceuticallyimpor-tantbecauseoftheirimmunostimulant[5],antifugal[6],antimicrobial[7]… 相似文献
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The title compound, C16H23N5O3S, ethyl 5-amino-1-(5‘-methyl-1‘-t-butyl-4‘-pyrazolyl)carbonyl-3-methylthio-1H-pyrazole-4-carboxylate (5) has been synthesized by the treatment of ethyl 2-cyano-3,3-dimethylthioacrylate with 1-t-butyl-5-methyl-4-hydrazinocarbonylpyrazole (4) in refluxed ethanol. The possible mechanism of the above reaction was also discussed. The results of biological test show that the title compound has fungicidal and plant growth regulation activities. 相似文献
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2-氨基-5-取代-1,3,4-噻二唑与2-氯代-1-(2,4-二氯苯基)乙酮的反应研究 总被引:1,自引:0,他引:1
2-氨基-5-烷基/芳基1,3,4-噻二唑与2-氯代-1-(2′,4′-二氯苯基)乙酮在热乙醇中反应生成一系列2-烷基/芳基-6-(4,4-二氯)苯基咪唑并[2-1-b]-1,3,4-噻二唑.产物通过元素分析, IR, 1H NMR, 13C NMR及MS分析,化合物5g的X衍射晶体结构分析表明,产物的芳基是在咪唑并[2-2-b]-1,3,4-噻二唑的6-位而不在5-位. 相似文献
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