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将十四周龄纯种Wistar大鼠雌雄各十只的背部毛彻底混匀。将各种洗涤剂用自来水或蒸馏水配成5%的溶液,把毛分别浸在不同溶液里,不时搅动,过夜。翌日,将浸入自来水洗涤溶液里的鼠毛用自来水冲洗30次,然后分别用蒸馏水和去离子水各冲洗10次,用一升蒸馏水分50~60次冲洗浸在蒸馏水洗涤溶液里的鼠毛后,再用去离子水冲洗10次。洗净的鼠毛经 相似文献
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Deoxycorticosterone acetate, injected daily for 5, 10, 20 or 30 days, reduced the serum potassium levels of rats by about 25%, a decrease that was independent of the treatment period employed. Serum sodium concentrations were unchanged with treatment duration. The potassium concentrations in extensor digitorum longus (EDL) and soleus (SOL) muscles were significantly decreased, and those of sodium increased, after treatment. Accompanying these changes of electrolyte concentration, the resting membrane potentials of treated EDL and SOL were hyperpolarized in vivo, and showed depolarization with the decreases of external potassium concentrations in vitro. The mitochondria in the muscles of treated rats were damaged. The degree of damage was more serious in EDL than in SOL and was dependent on the duration of deoxycorticosterone acetate treatment. 相似文献
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