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Xiao-Ye Jin Wei Cui Chong Chen Yu-Xin Guo Xing-Ru Zhang Guo-Hui Xing Jiang-Wei Lan Bo-Feng Zhu 《Electrophoresis》2020,41(13-14):1230-1237
Compound marker consists of two different types of genetic markers, like deletion/insertion polymorphism and single nucleotide polymorphism in the genomic region of 200 bp, and microhaplotype consists of a series of closely linked single nucleotide polymorphisms in a small DNA segment (<300 bp), which show great potential for human identifications and mixture analyses. In this study, we initially selected 23 novel genetic markers comprising 10 microhaplotypes and 13 compound markers according to previously reported single nucleotide polymorphism or deletion/insertion polymorphism loci. Genetic distributions of these 23 loci in different continental populations showed that they could be used as valuable loci for forensic human identification purpose. Besides, high informativeness values (>0.1) were observed in six loci which could be further employed for forensic ancestry analyses. Finally, 18 loci were successfully developed into a multiplex panel and detected by the next generation sequencing (NGS) technology. Further analyses of these 18 loci in the studied Shaanxi Han population showed that 15 loci exhibited relatively high expected heterozygosities (>0.5). Cumulative power of discrimination (0.999 999 999 99 4835) of these 18 loci revealed that the multiplex panel could also be utilized for human identifications in the studied Shaanxi Han population. 相似文献
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设$kge 2$是整数.如果对任意包含$k$个顶点的子集$Ssubseteq V(G)$,图$G$总存在一个生成树$T$ 使得$S$恰好是树$T$的叶子点集,那么称图$G$ 是$k$-叶子连通的.本文中,我们利用图$G$或其补图的第一Zagre-指标、第二Zagreb-指标和超Zagreb-指标证明了图是$k$-叶子连通的最佳可能的充分条件. 相似文献
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图G的一个L(2.1)-标号是从顶点集V(G)到非负整数的一个函数f,使得若d(u,v)=1时,有|f(u)-f(v)|≥2;若d(u,v)=2时,有|f(u)-f(v)|≥1.图G的L(2.1)-标号数λ(G)是G的所有L(2.1)-标号下的跨度max{f (v):v∈V(G)}的最小数.图F*n+1为扇图的路上每个... 相似文献
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阐述了在大学物理教学中引入非线性理论知识,特别是引入混沌控制和同步内容的重要性,这对于让学生完整理解混沌科学理论是非常必要的. 相似文献
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Kite-可分组设计的相交数问题是确定所有可能的元素对$(T,s)$, 使得存在一对具有相同组型 $T$ 的Kite-可分组设计 $(X,{cal H},{cal B}_1)$ 和$(X,{cal H},{cal B}_2)$ 满足$|{cal B}_1cap {cal B}_2|=s$. 本文研究组型为 $2^u$ 的Kite-可分组设计的相交数问题, 设 $J(u)={s:exists$ 组型为 $2^u$ 的Kite-可分组设计相交于$s$ 个区组}, $I(u)={0,1,ldots,b_{u}-2,b_{u}}$,其中 $b_u=u(u-1)/2$ 是组型为$2^u$ 的Kite-可分组设计的区组个数. 我们将给出对任意整数 $uge 4$ 都有$J(u)=I(u)$ 且 $J(3)= {0,3}$. 相似文献
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研究由一个供应商和销售商组成的供应链。销售商为中小企业,在受资金约束时无法通过自身信用获得所需融资,此时供应商可以为销售商贷款提供担保以提高其融资授信额度。本文采用销售商违约后剩余质押物的回购率来衡量供应商对融资风险的分担程度,对参与各方的存货质押融资决策进行了深入研究。结果表明:供应商的回购承诺提高了银行利润,在一定条件下提高了银行的质押率;并且,有回购承诺的融资决策在市场前景乐观情况下可以有效缓解销售商的融资困境。 相似文献
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本文对定积分和二重积分的几何意义进行了深入比较,通过实际问题的解决使学生更好地理解和掌握两种积分内在联系和区别,提高应用能力,培养创新意识. 相似文献