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1.
Refractory wounds have always been an important issue to healthcare systems, whose healing process is always delayed by multiple factors, including bacterial infections, chronic inflammation, and excessive exudates, etc. Employing multifunctional wound dressings is recognized as an effective strategy to deal with refractory wounds, which has yielded promising outcomes in recent years. Among these advanced wound dressings, fibrous dressings have gained growing attention due to their unique merits. Such wound dressings have demonstrated great potential in delivering theranostic agents, such as antibacterial agents, anti-inflammatory drugs, growth factors, and diagnostic probes, etc., for the purposes of accelerating wound healing. This paper reviews the development of multifunctional fibrous dressings and their applications in treating refractory wounds. The construction approaches of novel fibrous dressing with capabilities of antibacterial, anti-inflammation, exudate management and diagnosis were also introduced. Furthermore, the existing problems and challenges are also discussed briefly.  相似文献   
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Facile construction of sulfur-rich polymers using readily available raw chemicals is an area aggressively pursued but challenging. Herein we use common feedstocks of ethylene oxide (EO), propylene oxide (PO), and carbonyl sulfide (COS) to synthesize copoly(thioether)s which are traditionally produced from unpleasant and difficult to store episulfides. In this protocol, the EO/COS coupling selectively generates a pure poly(ethylene sulfide) (PES) with melting temperature (Tm) values up to 172°C and high yields up to 98%. The EO/PO/COS terpolymerization leads to the incorporation of soft poly(propylene sulfide) (PPS) and hard PES segments together, affording a random PES-co-PPS copoly(thioether) with the complete consumption of EO and PO. Additionally, by simply varying the EO/PO feeding ratio, the obtained copoly(thioether)s possess tunable thermal properties, Tm values in the range of 76–144°C, and excellent solubility. These copolymerizations are conducted in one-pot/one-step at industrially favored reaction temperatures of 100–120°C using catalysts of common organic bases, suggesting a facile and practical manner. Especially, the copoly(thioether) exhibits high refractive indices up to 1.68 owing to its high sulfur content, suggesting a broad application prospect in optical materials.  相似文献   
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柯荣住  张进 《运筹学学报》2021,25(3):87-104
本文首先对双层规划的一个特殊例子即道德风险模型中使用的一阶条件方法(FOA)做简要的梳理,然后提出一种更为一般的使FOA有效的原则与方法。新方法主要依赖于代理人对委托人设置的目标的最优反应映射是否存在不动点,这个性质不要求原问题与用一阶条件放松以后的问题之间的约束集等价,从而也不要求代理人的期望效用对行动具有全局凹性。在新方法下,可以用较为简单的方法证明FOA在以下两种情形之一有效,即如果分布函数是概率分布的凸组合或者分布函数来自某些特殊的指数族分布。  相似文献   
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Gradient coil (GC) vibration is the root cause of many problems in MRI adversely affecting scanner performance, image quality, and acoustic noise levels. A critical issue is that GC vibration will be significantly increased close to any GC mechanical resonances. It is well known that altering the dimensions of a GC fundamentally affects the mechanical resonances excited by the GC windings. The precise nature of the effects (i.e., how the resonances are affected) is however not well understood. The purpose of the present paper is to study how the mechanical resonances excited by closed whole-body Z-gradient coils are affected by variations in cylinder geometry. A mathematical Z-gradient coil vibration model recently developed and validated by the authors is used to theoretically study the resonance dynamics under variation(s) in cylinder: (i) length, (ii) mean radius, and (iii) radial thickness. The forced-vibration response to Lorentz-force excitation is in each case analyzed in terms of the frequency response of the GC cylinder's displacement. In cases (i) and (ii), the qualitative dynamics are simple: reducing the cylinder length and/or mean radius causes all mechanical resonances to shift to higher frequencies. In case (iii), the qualitative dynamics are much more complicated with different resonances shifting in different directions and additional dependencies on the cylinder length. The more detailed dynamics are intricate owing to the fact that resonances shift at comparatively different rates and this leads to several novel and theoretically interesting predicted effects. Knowledge of these effects advance our understanding of the basic mechanics of GC vibration and offer practically useful insights into how such vibration may be passively reduced.  相似文献   
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主要给出了偏缠绕模的Frobenius性质,推广了缠绕模相应的性质。  相似文献   
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Annals of the Institute of Statistical Mathematics - In this paper, a model averaging approach is developed for the linear regression models with response missing at random. It is shown that the...  相似文献   
9.
Jin  Zhuochen  Cao  Nan  Shi  Yang  Wu  Wenchao  Wu  Yingcai 《显形杂志》2021,24(2):349-364
Journal of Visualization - The increasing availability of spatiotemporal data provides unprecedented opportunities for understanding the structure of an urban area in terms of people’s...  相似文献   
10.
The accumulation of material degradation under contact with aggressive aqueous environments could lead to reduced structural reliability. In terms of hydrated cementitious materials, such interactions often result in the chemo-physical-mechanical (CPM) degradation, which represents a multiphysics process of high non-linearity and complexity. By further considering the inevitable uncertainties associated with both the materials and the serving conditions, solving such a process requires novel probabilistic approaches. This paper presents a stochastic chemo-physical-mechanical (SCPM) degradation analysis on the hydrated cement under acidic environment. The SCPM analysis consists of modelling the stochastic chemophysical degradation by finite element method, and assessing the mechanical deterioration through analytical micromechanics. The proposed modelling framework couples the conventional Monte Carlo Simulation with a novel support vector regression algorithm. The present method is able to not only address the detailed degradation mechanisms, but also ensure low computational costs for an accurate SCPM degradation assessment.  相似文献   
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