Combined wavelet transform-artificial neural network use in tablet active content determination by near-infrared spectroscopy

The pharmaceutical industry faces increasing regulatory pressure to optimize quality control. Content uniformity is a basic release test for solid dosage forms. To accelerate test throughput and comply with the Food and Drug Administration's process analytical technology initiative, attention is increasingly turning to nondestructive spectroscopic techniques, notably near-infrared (NIR) spectroscopy (NIRS). However, validation of NIRS using requisite linearity and standard error of prediction (SEP) criteria remains a challenge. This study applied wavelet transformation of the NIR spectra of a commercial tablet to build a model using conventional partial least squares (PLS) regression and an artificial neural network (ANN). Wavelet coefficients in the PLS and ANN models reduced SEP by up to 60% compared to PLS models using mathematical spectra pretreatment. ANN modeling yielded high-linearity calibration and a correlation coefficient exceeding 0.996.     

群决策中语言信息与其他4种偏好信息的一致化方法

研究语言信息与其他4种偏好信息(偏好次序,效用值,互反判断矩阵,互补判断矩阵)之间的相互转换问题.首先,根据各种偏好信息的实际意义,给出语言信息与他们之间的转换公式,并从理论上证明转换公式的合理性;其次,证明了若语言判断矩阵具有完全一致性,转换后的互反判断矩阵和互补判断矩阵也具有完全一致性;最后用实例验证了转换公式的有效性.     

The complexity of recursion theoretic games

We show that some natural games introduced by Lachlan in 1970 as a model of recursion theoretic constructions are undecidable, contrary to what was previously conjectured. Several consequences are pointed out; for instance, the set of all -sentences that are uniformly valid in the lattice of recursively enumerable sets is undecidable. Furthermore we show that these games are equivalent to natural subclasses of effectively presented Borel games.

     

Testing multivariate uniformity and its applications

Some new statistics are proposed to test the uniformity of random samples in the multidimensional unit cube These statistics are derived from number-theoretic or quasi-Monte Carlo methods for measuring the discrepancy of points in . Under the null hypothesis that the samples are independent and identically distributed with a uniform distribution in , we obtain some asymptotic properties of the new statistics. By Monte Carlo simulation, it is found that the finite-sample distributions of the new statistics are well approximated by the standard normal distribution, , or the chi-squared distribution, . A power study is performed, and possible applications of the new statistics to testing general multivariate goodness-of-fit problems are discussed.

     

Neighborhood assignments and cardinal functions: a unified approach to metrization and uniformity

We use neighborhood assignments and cardinal functions to give a unified approach to metrizability and uniformity. This leads to a number of characterizations of m(X), the metrizability degree of X, u(X), the uniform weight of X, and w(X), the weight of X. For X normal (and regular), m(X) = u(X); it is unknown whether this result extends to completely regular spaces.     

红外光学材料折射率均匀性的测量不确定度评定

基于多样品多型号仪器的测试信息及其GUM和MCM方法,讨论了四步干涉法测量红外光学材料折射率均匀性的测量范围及其测量不确定度评定。红外干涉测量的绝对灵敏度和准确度虽不及可见激光干涉仪,但采用了四步干涉测量的方法,消除了干涉仪的固有系统误差,有利于实现对红外光学材料折射率均匀性的高准确度测量。实际测试表明,该测量范围覆盖110-5～510-3,测量相对标准不确定度为210-1～210-2。     

氙灯光源太阳模拟器辐照衰减器设计方法

针对应用于太阳模拟器辐照衰减器设计上的不足,提出一种新的衰减器设计方法,旨在提高其辐照均匀性.基于光学扩展量计算衰减器上的网孔面积,对会聚光路的辐射通量进行调制;利用聚光镜环带法,理论上分析衰减器上的辐射分布;利用网孔非均匀分布的结构对会聚光路的辐射分布进行调制,给出具体设计参数;对比分析了网孔均匀分布和非均匀分布对辐...     

Nonspherical LED packaging lens for uniformity improvement

Light emitting diode (LED) has more advantages compared with a traditional incandescent light bulb and a fluorescent lamp, such as small size, low quantity of heat, long life, low power consumption, fast response, plain packaging and ease of develop ment of a frivolous short product. A methodology is proposed to improve the uniformity of the LED illumination system. As a light source in a backlight unit (BLU), the requirement for optical characteristics of a LED is different from highly directional conventional ones. New diffused-type LEDs need to be developed to fulfill the requirement of the BLU industry. A non-spherical lens is designed to optimize uniformity, and a great improvement in uniformity from 28.4 to 64% is demonstrated. In the future, it may used in an LED display to improve the unevenness of illumination.     

大视场CCD成像系统像面均匀性测试技术研究

以光度学为理论基础,研究了大视场CCD成像系统像面均匀性测试技术。论述了600~800mm非对称、双半球不等半径积分球的设计方案。对像面均匀性测试系统的积分球出口进行了测试,出口处的照度不均匀性不高于2.3%,照度不稳定性不高于2.7%,积分球后半球内表面的亮度不均匀性不高于4.4%。在对测试结果进行误差分析的基础上,对大视场CCD摄像机进行了实际测试。结果表明,该装置可广泛应用于光电成像系统的像面均匀性测量。     

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引进了美国GAMMA公司的高精度数字式可调标准光源RS-5B,并对其性能参数进行了测试。结果表明,该光源光强空间分布非常稳定,在光强大于0.001μW•cm-2时,复位性优于1%;在光强大于0.01μW•cm-2时,稳定性优于0.5%。其输出光强与标称值呈线性分布关系。这些优良的参数和特性满足聚变物理标定研究中对标定源的需求,为物理实验数据分析和计算模拟提供了条件。