文物铜车马部分残件的分析测试

对秦陵一号铜车马材质取样,采用电感偶合等离子体发射光谱法和塞曼石墨炉原子吸收光度法对其元素定性和定量分析;用光学金相显微镜扫描电镜观察金相组织状态;用能谱分析研究工艺;用X－射线衍射研究铜合金的组成结构和物相;配合电子探针做微区分析。分析的结果为铜车马的修复和保护起到了至关作用。     

饵料对幼海马生长的影响

在人工养殖条件下，幼海马对投喂的饵料具有选择性，不同的饵料对幼海马生长和成活影响很大。幼海马在不同生长阶段摄食不同的饵料，随着幼海马体长增加，捕食对象也逐渐增大。根据幼海马胃内含物的检出率和占胃率发现，刚出生的幼海马适宜饵料为轮虫和单细胞藻类，随后最适饵料逐渐变为枝角类、桡足类。当幼海马能摄食枝角类和桡足类后，生长速度加快，这两类饵料生物在幼海马胃内总占胃率与生长速度的关系式为：y＝8．93431n x-18．6628(r＝0．9021，r0.05＝0．8780，r＞r0.05)。     

竹红菌甲素与血红蛋白相互作用光谱

竹红菌甲素与血红蛋白相互作用光谱;马心血红蛋白;竹红菌甲素;相互作用;UV-Vis吸收光谱;荧光光谱;荧光猝灭动力学常数     

基于四粒子Ω态的量子对话方案及拦截-重发攻击安全性分析

提出了一个多用户量子信令树型传输系统,并详细阐述了信令的传输过程.研究了系统中信令受到特洛伊木马攻击的损伤模型及其修复的必要性.将量子密钥分发的思想引入量子信令安全的直接通信中,分析了采用非正交量子态,以克服特洛伊木马攻击的问题,从而提高了信令传输的安全性.对多用户量子信令树型传输系统进行改进,提出了新的广义的多用户量子信令树型拓扑传输模型.研究结果表明,本文所提出的对多用户信令攻击的修复策略可有效地防止特洛伊木马攻击,从而保证信令传输过程安全有效的进行.     

四足马机器人静步行稳定性实时检测与自调整方法

针对四足马机器人静步行中的的稳定性问题,提出了一种基于压力中心的实时检测方法.得到了静步行稳定性的定量化计算方法.基于检测到的稳定度和压力中心,提出了采用模糊推论实现静步行中的步行稳定性自调整的方法.自制小型四足马机器人,并进行了不同地面的静步行实验.结果证明所提方法能实现四足马机器人的静步行稳定性检测与自调整功能,并能有效提高四足马机器人静步行的稳定性.     

Enzymatic Preparation of Coniferaldehyde from Coniferyl Benzoate ex. Siam Benzoin

Siam benzoin is a natural resin that contains up to 65% of coniferyl benzoate. Treatment of this material with an esterase followed by an alcohol dehydrogenase in a one-pot procedure gave 1.5 g/L coniferaldehyde in 36% molar yield. Several lipases and esterases were tested, but only pig liver esterase gave significant results. Various alcohol oxidases and alcohol dehydrogenases were screened for their ability to oxidize coniferyl alcohol to coniferaldehyde. Horse liver alcohol dehydrogenase coupled with a cofactor regeneration system was the most efficient of the enzymes tested.     

Use of fluorinated functionality in enzyme inhibitor development: Mechanistic and analytical advantages

On the one hand, owing to its electronegativity, relatively small size, and notable leaving group ability from anionic intermediates, fluorine offers unique opportunities for mechanism-based enzyme inhibitor design. On the other, the “bio-orthogonal” and NMR-active 19-fluorine nucleus allows the bioorganic chemist to follow the mechanistic fate of fluorinated substrate analogues or inhibitors as they are enzymatically processed. This article takes an overview of the field, highlighting key developments along these lines. It begins by highlighting new screening methodologies for drug discovery that involve appropriate tagging of either the substrate or an array of potential substrates (i.e. in proteomics screens) with ¹⁹F-markers that then report back on turnover and function, respectively, via the NMR screen. Taking this one step further, substrate-tagging with fluorine can be done in such a manner as to provide stereochemical information on enzyme mechanism. For example, substitution of one of the terminal hydrogens in phosphoenolpyruvate, provides insight into the, otherwise latent, facial selectivity of CC bond formation in KDO synthase. Perhaps, most importantly, from the point of view of this discussion, appropriately tailored fluorinated functionality can be used to form stabilized “transition state analogue” complexes with target enzymes. Thus, 5-fluorinated pyrimidines, α-fluorinated ketones, and 2-fluoro-2-deoxysugars each lead to covalent adduction of catalytic active site residues in thymidylate synthase (TS), serine protease and glycosidase enzymes, respectively. In all such cases, ¹⁹F NMR allows the bioorganic chemist to spectrally follow “transition state analogue” formation. Finally, the use of specific fluorinated functionality to engineer “suicide substrates” is highlighted in a discussion of the development of the α-(2′Z-fluoro)vinyl trigger for amino acid decarboxylase inactivation. Here ¹⁹F NMR allows the bioorganic chemist to glean useful partition ratio data directly from the NMR tube.     

物理型硬件木马失效机理及检测方法

对两种物理型硬件木马造成芯片退化或失效的机理进行了详细分析. 通过使用ATLAS 二维器件仿真系统并结合SmartSpice电路逻辑仿真器, 模拟了两种物理型硬件木马对反相器逻辑电路输出特性的影响. 使用ATHENA工艺仿真系统模拟了掺杂离子注入工艺过程, 实现了掺杂型硬件木马的金属-氧化物-半导体场效应管(MOSFET)器件; 使用热载流子注入退化模型对ATLAS 仿真器件进行热载流子压力测试, 以模拟热载流子注入型硬件木马注入MOSFET器件并造成器件退化失效的过程, 分别将上述掺杂型硬件木马和热载流子注入型硬件木马的MOSFET器件与另一个正常MOSFET器件组成同样的反相器逻辑电路. 反相器使用Spice 逻辑电路仿真输出DC直流、AC瞬态传输特性以研究物理型硬件木马对电路输出特性的影响. 为了研究MOSFET器件的物理特性本身对硬件木马的影响, 在不同温度不同宽长比(W/L)下同样对反相器进行Spice电路逻辑输出仿真. 本文分析了离子掺杂工艺、热载流子注入压力测试形成的物理型硬件木马随压力强度、温度的变化对逻辑电路输出特性的影响. 通过结果对比分析得出了含有物理型硬件木马的逻辑电路在DC直流输出特性上的扰动比AC瞬态传输特性更明显的结论. 因此, 本文提出了一种针对物理型硬件木马的检测流程. 同时, 该检测流程是一种具有可操作性的检测物理型硬件木马的方法.     

试以公孙龙"白马非马"命题思辨武术套路节奏

节奏是武术套路运动中的一个重要特点.针对许多人对武术套路节奏认识的单一化、片面化,笔者以公孙龙的“白马非马”命题出发,从形式逻辑角度和哲学角度对此展开阐述,以使人们能够更加全面地理解武术套路的节奏问题,正确理解和认识节奏在武术运动中的重要性.     

Highly Amino Acid Selective Hydrolysis of Myoglobin at Aspartate Residues as Promoted by Zirconium(IV)‐Substituted Polyoxometalates

SDS‐PAGE/Edman degradation and HPLC MS/MS showed that zirconium(IV)‐substituted Lindqvist‐, Keggin‐, and Wells–Dawson‐type polyoxometalates (POMs) selectively hydrolyze the protein myoglobin at Asp? X peptide bonds under mildly acidic and neutral conditions. This transformation is the first example of highly sequence selective protein hydrolysis by POMs, a novel class of protein‐hydrolyzing agents. The selectivity is directed by Asp residues located on the surface of the protein and is further assisted by electrostatic interactions between the negatively charged POMs and positively charged surface patches in the vicinity of the cleavage site.