基于MIDAS的某带端部转换剪力墙结构的抗震性能分析

文章以某高层剪力墙结构带端部转换为例,采用有限元软件MIDAS/Building进行多遇地震下的弹性计算、罕遇地震下的弹塑性分析及楼板应力分析,对托墙转换构件采用小震、中震弹性双控设计,对结构整体及构件的抗震性能进行评估。计算结果表明,通过加强措施后,结构布置合理,无明显刚度薄弱层和过大扭转位移比,结构具有良好的屈服机制。     

基于MATLAB的发酵液恒压过滤比阻计算方法——以解淀粉芽孢杆菌Q-426发酵液为例

介绍了用MATLAB的Curve Fitting Toolbox计算解淀粉芽孢杆菌Q-426发酵液恒压过滤比阻的方法。通过在图形界面下导入恒压过滤实验数据及平滑处理、采用平滑样条拟合数据以及数值微分等操作,确定了解淀粉芽孢杆菌Q-426发酵液恒压过滤的滤饼比阻。研究表明,该方法运行可靠,无需编程,易于掌握。与传统计算方法相比,操作更为便捷,强有力的图形界面也使计算变得更加简单而直观。     

Development of a manufacturing process for the drug fenleuton

A new strategy for a large scale synthesis is developed and evaluated by the improvement of the current synthesis for fenleuton, a drug with important applications in leukotriene-mediated inflammatory diseases that acts through inhibition of the 5-lipoxygenase enzyme.     

Comparison of antimicrobial peptide purification via free‐flow electrophoresis and gel filtration chromatography

Antimicrobial peptides (AMPs) are usually small and cationic biomolecules with broad‐spectrum antimicrobial activities against pathogens. Purifying them from complex samples is essential to study their physiochemical properties. In this work, free‐flow zone electrophoresis (FFZE) was utilized to purify AMPs from yeast fermentation broth. Meanwhile, gel filtration chromatography (GFC) was conducted for comparison. The separation efficiency was evaluated by SDS‐PAGE analysis of the fractions from both methods. Our results demonstrated as follows: (i) FFZE had more than 30‐fold higher processing capacity as compared with GFC; (ii) FFZE could achieve 87% purity and 89% recovery rate while in GFC these parameters were about 93 and 82%, respectively; (iii) the former had ∼2‐fold dilution but the latter had ∼13‐fold dilution. Furthermore, Tricine‐SDS‐PAGE, Native‐PAGE, and gel IEF were carried out to characterize the purified AMPs. We found that two peptides existed as a pair with the molecular mass of ∼5.5 and 7.0 kDa, while the same pI 7.8. These two peptides were proved to have the antimicrobial activity through the standardized agar diffusion method. Therefore, FFZE could be used to continuously purify AMPs with high bioactivity, which will lead to its wide application in the clinical and pharmaceutical fields.     

Effective Permeabilities in a Porous Medium with Log-Stable Statistics

Equations for the effective coefficients of random permeability fields for fluid flow through a porous medium with log-stable distributions are derived using the Wilson renormalization group approach. Results of the theoretical modeling are compared with data of numerical modeling. __________ Translated from Prikladnaya Mekhanika i Tekhnicheskaya Fizika, Vol. 46, No. 6, pp. 146–158, November–December, 2005.     

ASYMPTOTIC NON-STABILITY AND BLOW-UP AT BOUNDARY FOR SOLUTIONS OF A FILTRATION EQUATION

For a class of nonlinear filtration equation with nonlinear second-third boundary value condition, it is shown that a priori boundary of the solution can be estimated and controlled by initial data and integral on the boundary of the region. The priori estimate of the solutions was established by iterative method. By using this estimate the solutions may blow-up on the boundary of the region and thus it may have asymptotic non-stability.     

基于转移函数的移动网络海量数据隐私泄露检测技术

移动终端网络数据规模大,采用传统方法对海量数据隐私泄露进行检测时,无法保证网络中所有查询结果均参与运算,不能保证检测结果的准确性。为此,提出一种新的移动终端网络海量数据隐私泄露检测方法。把设计系统安装于移动运营商核心网,构建检测系统模型。将半格看作数据分析方式,通过半格元素对移动终端网络数据信息进行描述。采集程序中和变量使用相关的信息,对数据在基本块间传输与修改过程进行研究,实现对所有移动终端网络数据的分析。令全部查询结果参与运算。前向遍历基本块中的函数,依据函数类别,按基本块内污点规则对污点数据与漂白污点数据施行更新。获取转移函数,将转移函数应用于格值,得到隐私泄露数据。依据T-D法建立隐私泄露检测模型,对其进行优化,获取K-匿名隐私泄露检测模型。通过K-Q法对其进行求解,实现移动终端网络海量数据隐私泄露检测。实验结果表明,相对于传统方法,检测准确性较高,具有广泛的应用价值。     

Existence and attractivity of time periodic solutions for Nicholson's blowflies model with nonlinear diffusion

This paper is concerned with the existence and attractivity of time periodic solutions for one‐dimensional Nicholson's blowflies model with nonlinear diffusion. By constructing some suitable Lyapunov functionals and combining with Leray–Schauder fixed point theorem, we establish the existence of nonnegative time periodic solutions. Using the method of upper and lower solutions and its associated monotone iterations, we obtain the existence of the attractor for this model. Copyright © 2013 John Wiley & Sons, Ltd.     

Oscillatory traveling waves of polytropic filtration equation with generalized Fisher–KPP sources

The polytropic filtration equation with generalized Fisher–KPP sources is considered. We will show that the equation may have finite times oscillatory traveling waves, and try to give a complete classification by virtue of a singular exponent in the source according to the finiteness of the oscillatory times of traveling waves.     

Convergence of Yang-Mills-Higgs flow for twist Higgs pairs on Riemann surfaces

We consider the gradient flow of the Yang-Mills-Higgs functional of twist Higgs pairs on a Hermitian vector bundle(E,H)over Riemann surface X.It is already known the gradient flow with initial data(A0,φ0)converges to a critical point(A∞,φ∞).Using a modified Chern-Weil type inequality,we prove that the limiting twist Higgs bundle(E,d′′A∞,φ∞)coincides with the graded twist Higgs bundle defined by the HarderNarasimhan-Seshadri filtration of the initial twist Higgs bundle(E,d′′A0,φ0),generalizing Wilkin’s results for untwist Higgs bundle.