全文获取类型
收费全文 | 3827篇 |
免费 | 459篇 |
国内免费 | 246篇 |
专业分类
化学 | 786篇 |
晶体学 | 29篇 |
力学 | 72篇 |
综合类 | 24篇 |
数学 | 451篇 |
物理学 | 818篇 |
综合类 | 2352篇 |
出版年
2024年 | 17篇 |
2023年 | 65篇 |
2022年 | 128篇 |
2021年 | 123篇 |
2020年 | 134篇 |
2019年 | 114篇 |
2018年 | 74篇 |
2017年 | 114篇 |
2016年 | 142篇 |
2015年 | 128篇 |
2014年 | 216篇 |
2013年 | 286篇 |
2012年 | 209篇 |
2011年 | 244篇 |
2010年 | 195篇 |
2009年 | 187篇 |
2008年 | 194篇 |
2007年 | 226篇 |
2006年 | 218篇 |
2005年 | 178篇 |
2004年 | 177篇 |
2003年 | 179篇 |
2002年 | 131篇 |
2001年 | 123篇 |
2000年 | 102篇 |
1999年 | 86篇 |
1998年 | 64篇 |
1997年 | 77篇 |
1996年 | 70篇 |
1995年 | 49篇 |
1994年 | 61篇 |
1993年 | 35篇 |
1992年 | 22篇 |
1991年 | 27篇 |
1990年 | 28篇 |
1989年 | 19篇 |
1988年 | 21篇 |
1987年 | 18篇 |
1986年 | 11篇 |
1985年 | 7篇 |
1984年 | 7篇 |
1983年 | 2篇 |
1982年 | 10篇 |
1981年 | 3篇 |
1980年 | 2篇 |
1979年 | 2篇 |
1978年 | 2篇 |
1975年 | 1篇 |
1973年 | 1篇 |
1955年 | 1篇 |
排序方式: 共有4532条查询结果,搜索用时 15 毫秒
1.
Pattern transition and regulation in a subthalamopallidal network under electromagnetic effect
下载免费PDF全文
![点击此处可从《中国物理 B》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Although the significant roles of magnetic induction and electromagnetic radiation in the neural system have been widely studied, their influence on Parkinson's disease (PD) has yet to be well explored. By virtue of the magnetic flux variable, this paper studies the transition of firing patterns induced by magnetic induction and the regulation effect of external magnetic radiation on the firing activities of the subthalamopallidal network in basal ganglia. We find: (i) The network reproduces five typical waveforms corresponding to the severity of symptoms: weak cluster, episodic, continuous cluster, episodic, and continuous wave. (ii) Magnetic induction is a double-edged sword for the treatment of PD. Although the increase of magnetic coefficient may lead the physiological firing activity to transfer to pathological firing activity, it also can regulate the pathological intensity firing activity with excessive β-band power transferring to the physiological firing pattern with weak β-band power. (iii) External magnetic radiation could inhibit continuous tremulous firing and β-band power of subthalamic nucleus (STN), which means the severity of symptoms weakened. Especially, the bi-parameter plane of the regulation region shows that a short pulse period of magnetic radiation and a medium level of pulse percentage can well regulate pathological oscillation. This work helps to understand the firing activity of the subthalamopallidal network under electromagnetic effect. It may also provide insights into the mechanisms behind the electromagnetic therapy of PD-related firing activity. 相似文献
2.
Kai Cheng Xiao-Shuai Zhang Jie An Cheng Li Ruo-Yun Zhang Run Ye Prof. Dr. Bang-Jiao Ye Prof. Dr. Bo Liu Prof. Dr. Yuan-Di Zhao 《Chemistry (Weinheim an der Bergstrasse, Germany)》2019,25(31):7553-7560
Given their superior penetration depths, photosensitizers with longer absorption wavelengths present broader application prospects in photodynamic therapy (PDT). Herein, Ag2S quantum dots were discovered, for the first time, to be capable of killing tumor cells through the photodynamic route by near-infrared light irradiation, which means relatively less excitation of the probe compared with traditional photosensitizers absorbing short wavelengths. On modification with polydopamine (PDA), PDA-Ag2S was obtained, which showed outstanding capacity for inducing reactive oxygen species (increased by 1.69 times). With the addition of PDA, Ag2S had more opportunities to react with surrounding O2, which was demonstrated by typical triplet electron spin resonance (ESR) analysis. Furthermore, the PDT effects of Ag2S and PDA-Ag2S achieved at longer wavelengths were almost identical to the effects produced at 660 nm, which was proved by studies in vitro. PDA-Ag2S showed distinctly better therapeutic effects than Ag2S in experiments in vivo, which further validated the enhanced regulatory effect of PDA. Altogether, a new photosensitizer with longer absorption wavelength was developed by using the hitherto-unexplored photodynamic function of Ag2S quantum dots, which extended and enhanced the regulatory effect originating from PDA. 相似文献
3.
“百病生于气”见于《素问·举痛论》,几千年来始终是中医临床认识疾病、防治疾病的重要理论依据之一。对气的含义及气机失调致病的机制进行了梳理,得出了“百病生于气”的基本含义可以概括为气机失调是疾病发生的基本病机的结论,情志因素、精神心理是导致疾病发生的重要内因。分析认为“百病生于气”的理论对于针灸临床有重要指导意义,针灸诊疗过程中应注重“调气”“调神”,这是针灸取得佳效的根本保障。 相似文献
4.
ABSTRACTQM(UB3LYP)/MM(AMBER) calculations were performed for the locations of the transition structure (TS) of the oxygen–oxygen (O–O) bond formation in the S4 state of the oxygen-evolving complex (OEC) of photosystem II (PSII). The natural orbital (NO) analysis of the broken-symmetry (BS) solutions was also performed to elucidate the nature of the chemical bonds at TS on the basis of several chemical indices defined by the occupation numbers of NO. The computational results revealed a concerted bond switching (CBS) mechanism for the oxygen–oxygen bond formation coupled with the one-electron transfer (OET) for water oxidation in OEC of PSII. The orbital interaction between the σ-HOMO of the Mn(IV)4–O(5) bond and the π*-LUMO of the Mn(V)1=O(6) bond plays an important role for the concerted O–O bond formation for water oxidation in the CaMn4O6 cluster of OEC of PSII. One electron transfer (OET) from the π-HOMO of the Mn(V)1=O(6) bond to the σ*-LUMO of the Mn(IV)4–O(5) bond occurs for the formation of electron transfer diradical, where the generated anion radical [Mn(IV)4–O(5)]-? part is relaxed to the ?Mn(III)4?…?O(5)- structure and the cation radical [O(6)=Mn(V)1]+ ? part is relaxed to the +O(6)–Mn(IV)1? structure because of the charge-spin separation for the electron-and hole-doped Mn–oxo bonds. Therefore, the local spins are responsible for the one-electron reductions of Mn(IV)4->Mn(III)4 and Mn(V)1->Mn(IV)1. On the other hand, the O(5)- and O(6)+ sites generated undergo the O–O bond formation in the CaMn4O6 cluster. The Ca(II) ion in the cubane- skeleton of the CaMn4O6 cluster assists the above orbital interactions by the lowering of the orbital energy levels of π*-LUMO of Mn(V)1=O(6) and σ*-LUMO of Mn(IV)4–O(5), indicating an important role of its Lewis acidity. Present CBS mechanism for the O–O bond formation coupled with one electron reductions of the high-valent Mn ions is different from the conventional radical coupling (RC) and acid-base (AB) mechanisms for water oxidation in artificial and native photosynthesis systems. The proton-coupled electron transfer (PC-OET) mechanism for the O–O bond formation is also touched in relation to the CBS-OET mechanism. 相似文献
5.
6.
光突发交换的交换控制策略和光缓存配置 总被引:4,自引:2,他引:2
光突发交换是面向下一代互联网的光交换模式.讨论了异步光突发交换系统的交换控制策略以及相应光缓存的优化配置策略.除了传统预约模式的交换策略,还研究了非预约和改进型预约模式,它们的性能评估由计算机仿真给出.结果表明:在条件相当情况下,改进型预约模式具有最低的丢包率.同时光缓存的配置对上述几类交换控制策略的性能都有很大影响,仿真结果指出:光缓存的粒度对系统性能具有重要影响,所讨论的几类交换模式都存在最佳时延粒度,研究结果对光交换矩阵的设计有指导意义. 相似文献
7.
8.
本文首先阐述了管制的概念内涵以及进行管制的必要性 ,并对影响管制的主要因素进行分析 .随后运用管制经济学和规范经济学的基本理论 ,考察公路货运业行业管制制度的变迁与管制效果 ,对管制失效的原因加以分析 .最后对加入 WTO后如何对公路运输行业进行管制加以探讨 相似文献
9.
In this paper, a series of examples from China, including those using ecological regulation strategies successfully to keep crop pests under control and those making more damages of crop pests caused by wrong cropping systems, crop distributions or extensive cultivation, were given and analyzed. From these, two pieces of experience were enlightened as follows: the first, the refoms of cropping systems and crop distributions must be beneficial to pest control or at least not increase the damage of crop pests; the second, we should further clarify the relationship between population dynamics of pests and cropping system/crop distribution, the basis for correctly laying down the ecological regulation systems. 相似文献
10.
姚仲敏 《齐齐哈尔大学学报(自然科学版)》2003,19(4):74-76
采用Authorware6.0多媒体制作软件为开发工具,进行程控交换原理多媒体CAI课件的开发,该课件提供一个内容学习平台——利用动画效果讲解原理;提供一个创新教育平台——便于学生主动参与和自我激励。该课件在教学实践中试用,具有界面友好、操作方便、运行稳定等优点。 相似文献