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严德明 《中南大学学报(自然科学版)》1993,(5)
采空区掘进充填井是一次回采嗣后块石胶结充填采矿法的关键。如不解决,采空区将不断扩大,势必造成地压危害和残留空场硫铁矿矿石氧化自然发火。而新桥硫铁矿采空区已达10~4m~3以上。解决采空区充填井已是燃眉之急。采用SQZ-1型潜孔钻车钻凿深孔而后分段爆破成充填井的成功,既解决了新桥矿采空区充填问题,又解决了其他方法不能掘进采空区充填井的问题,对类似矿山有较大的推广应用价值。 相似文献
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R. S. Martynov Yu. M. Nechepurenko 《Computational Mathematics and Mathematical Physics》2006,46(7):1155-1167
For a discrete linear stochastic dynamical system, computation of the response matrix to the external action from a subspace using given observational data is examined. An algorithm is proposed and substantiated that makes it possible to improve the numerical accuracy and to reduce the amount of observational data compared to the general case where an arbitrary external action is allowed. As an illustration, a discrete system arising in the analysis of a linear stochastic dynamical continuous-time system is considered more thoroughly. Some numerical results are presented. 相似文献
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Science Letters: A synthetic Toll-like receptor 2 ligand decreases allergic immune responses in a mouse rhinitis model sensitized to mite allergen
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It has been proposed that activation of Toll-like receptors (TLRs) plays crucial roles in the polarization of adaptive immune responses. A synthetic Toll-like receptor 2 (TLR2) ligand, Pam3CSK4, has been reported to modulate the balance of Th1/Th2 responses. We evaluated the modulation effect of Pam3CSK4 on allergic immune response in a mouse rhinitis model sensitized to house dust mite allergen (HDM). Mice were sensitized and challenged with Dermatophagoidesfarinae allergen (Der f), and then the allergic mice were treated by Pam3CSK4. Nasal allergic symptoms and eosinophils were scored. Der f-specific cytokine responses were examined in the splenocytes and bronchoalveolar lavage fluid (BALF). Serum level of total IgE was also detected. After establishing a mouse allergic rhinitis model with HDM, we have showed that Pam3CSK4 treatment not only ameliorated the nasal allergic symptoms remarkably but also decreased the eosinophils and total inflammation cells in BALF significantly. Analysis of cytokine profile found that IFN-7 released from either BALF or stimulated splenocytes increased markedly in Pam3CSK4-treated mice, while IL-13 decreased significantly. Moreover, serum level of total IgE was significantly lower in Pam3CSK4-treated mice than in the untreated. Thus, in an allergic rhinitis mouse model developed with HDM, Pam3CSK4 was shown to exhibit an antiallergic effect, indicating its potential application in allergic diseases. 相似文献
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用于强磁场的快响应真空规的研制进展 总被引:2,自引:2,他引:0
研制了能在强磁场、强干扰环境下工作的快响应真空电离规(快规),用于对HL 2A装置偏滤器室和等离子体附近的中性粒子密度和通量进行原位测量。介绍了快规的结构、工作原理、设计要点以及实验结果。在无磁场的情况下,快规对气体压强的测量范围为6.4×10-6~0.15Pa,在1×10-5~0.15Pa范围内,快规收集极离子流与发射电子流之比与气压保持良好线性关系;在0 15T的磁场下,快规的规管常数未发生显著变化,在规管对称轴与磁力线的夹角小于15o时,规管常数的变化小于10%。 相似文献
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The paper presents a new formulation of the integral boundary element method (BEM) using subdomain technique. A continuous approximation of the function and the function derivative in the direction normal to the boundary element (further ‘normal flux’) is introduced for solving the general form of a parabolic diffusion‐convective equation. Double nodes for normal flux approximation are used. The gradient continuity is required at the interior subdomain corners where compatibility and equilibrium interface conditions are prescribed. The obtained system matrix with more equations than unknowns is solved using the fast iterative linear least squares based solver. The robustness and stability of the developed formulation is shown on the cases of a backward‐facing step flow and a square‐driven cavity flow up to the Reynolds number value 50 000. Copyright © 2004 John Wiley & Sons, Ltd. 相似文献
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A solution to the phase problem in optics is considered within the context of the analysis of signals changing in time and of the effect of an object under investigation on the probing radiation. The solution is based on the use of a twin-wave interferometer with phase modulation in one of the channels and a spectrometer. The analysis is concerned, in particular, with signals and processes of ultrashort duration. To shift the frequency in the interferometer channel, an electrooptical crystal of ferroelectric perovskite is used as the modulator. Errors of amplitude and phase structures determined are analyzed. 相似文献