新疆植物物种多样性的特点分析

新疆土地面积占全国１／６,约１６４．６８万ｋｍ２,位于欧亚大陆腹地,景观与地形复杂,气候变化明显,植物种质资源特殊。新疆高等植物４０８１种（包括２２９亚种、变种与变型）,隶属于１６１科８７７属,新疆植物多样性的特点如下：１）单种科、单种属及寡种属丰富,分别为８０科、３７４属及３１５属。２）短命及类短命植物丰富,已知的有２３２种,隶属于２７科１１４属,主要分布于准噶尔盆地边缘。３）新疆特有种稀少,但中国、塔什库尔干、天山、阿尔泰山、昆仑山及帕米尔高原的特有种特别丰富。４）近５０年以来,发表的新疆新分类群较多,有３６０余种。５）中国仅分布于新疆的植物有１７７３种,其中１００种以上的科有４科（豆科,伞形科,菊科,禾本科）,总数为６２２种;８０种以上的科也有４科,总数为３３１种。最后,对新疆极端环境下的植物种质资源及栽培植物的野生近缘种的保护问题提出了几点建议。     

云南楚雄市鸟类多样性的研究

对楚雄市鸟类栖息环境：即城市市区,城市绿化区,工矿区,农田耕作区,自然保护区的调查,共记录鸟类７２种,隶属于１３目２６科,总计１１４２只个体,并运用物种多样性测定法（Ｓｈａｎｎｏｎｗｅａｖｅｒ指数和Ｓｉｍｐｓｎ指数）评价各环境中鸟类多样性,讨论了有关鸟类物种多样性与栖息环境的关系及其与人类活动干扰程度的关系．     

贺兰山苔藓植物物种多样性,生物量及生态学作用的研究

研究了贺兰山不同海拔高度主要林型种苔藓植物物种多样性,生物量和生态学作用,结果表明,云杉林下藓类地层的生物量最高,９１４７．７ｋｇ／ｈｍ＾２,是林灌木和草本植物总生物量的９．２倍,在饱和吸水状态下,可贮存水２０１７４．５ｋｇ／ｈｍ＾２,通过随机取样按海拔高度,林型和土壤类型等梯度对贺兰苔藓植物被进行了调查,影响苔藓植物生长和分布的主要生态因子是光照,相对湿度,海拔高度和土壤ｐＨ对出现在群落中包拓苔     

From solution-phase to solid-phase enyne metathesis: crossover in the relative performance of two commonly used ruthenium pre-catalysts

A crossover in the ability of two distinct ruthenium-based metathesis pre-catalysts to effect the synthesis of dialkenylboronic esters in solution and on the solid-phase was observed. Specifically, while the Grubbs 2nd generation pre-catalyst 3 affords a greater degree of conversion to product than the Hoveyda-Grubbs pre-catalyst 2 in a solution-phase enyne-metathesis reaction, this trend is reversed in the solid-phase variant. Systematic investigation showed this trend to be general, regardless of variations in the homoallylic alcohol and alkynylboronic ester components of the reaction, as well as in the type of solid support employed. Experiments to determine a mechanistic hypothesis for this trend highlighted the significance of the ruthenium remaining bound to the substrate after metathetic rearrangement and found the presence of phosphine ligand to be detrimental to the success of the solid-phase reaction. Therefore, these results suggest an expanded role for phosphine-free pre-catalysts, such as 2, in challenging solid-phase metathesis reactions.     

A planning strategy for diversity-oriented synthesis

In contrast to target-oriented synthesis (TOS) and medicinal or combinatorial chemistry, which aim to access precise or dense regions of chemistry space, diversity-oriented synthesis (DOS) populates chemical space broadly with small-molecules having diverse structures. The goals of DOS include the development of pathways leading to the efficient (three- to five-step) synthesis of collections of small molecules having skeletal and stereochemical diversity with defined coordinates in chemical space. Ideally, these pathways also yield compounds having the potential to attach appendages site- and stereoselectively to a variety of attachment sites during a post-screening, maturation stage. The diverse skeletons and stereochemistries ensure that the appendages can be positioned in multiple orientations about the surface of the molecules. TOS as well as medicinal and combinatorial chemistries have been advanced by the development of retrosynthetic analysis. Although the distinct goals of DOS do not permit the application of retrosynthetic concepts and thinking, these foundations are being built on, by using parallel logic, to develop a complementary procedure known as forward-synthetic analysis. This analysis facilitates synthetic planning, communication, and teaching in this evolving discipline.     

Synthesis of β3‐Homophenylalanine‐Derived Amino Acids and Peptides by Suzuki Coupling in Solution and on Solid Support

β‐Peptides and, to a certain extent, also mixed α,β‐peptides, are resistant to degradation by a variety of proteolytic enzymes that rapidly degrade natural α‐peptides. This is one of many characteristics that make β‐peptides an attractive class of compounds for drug‐discovery studies. On the other hand, modern organometallic reactions such as the Suzuki–Miyaura cross‐coupling have become standard tools in industry laboratories to derivatize side chains of α‐peptidic compounds to build up libraries of unnatural peptides. Combining both features, we prepared (4‐bromo)‐β³‐homophenylalanine derivatives 3 – 5 and 12 as precursors for Suzuki–Miyaura couplings. From these bromo compounds, we synthesized biaryl‐substituted β‐homoamino acids 6 , and analogs 13 and 15 of the anti‐AIDS drug Saquinavir.     

G蛋白偶联受体研究进展

G蛋白偶联受体（GPCRs）是体内最大的蛋白质超家族，根据结构的同源性，主要分为A、B、C3族．GPCRs配体的多样性决定配体结合域的多样性．受体分子内相互作用力的破坏、质子化、构象改变、与G蛋白的偶联及受体二聚化参与了GPCRs的活化过程，近年发现GPCRs的失敏和内吞对受体功能调节亦非常重要，本文拟综述以上内容的研究进展．     

唐家河国家级自然保护区夏季啮齿动物的群落分析

2003年7-8月应用样线铗日法对唐家河自然保护区夏季啮齿动物的群落结构进行了调查，共捕获啮齿动物220只，根据生境状况、物种组成和优势种将其归为4个群落，并根据各群落的优势种进行了命名，采用Shannon-Wiener多样性指数、Pielou均匀性指数、Simpson的优势度指数和Whittaker相似性指数，分析了该保护区夏季不同海拔高度啮齿动物群落的结构特点，结果表明群落多样性指数和均匀性指数最大的都是位于中海拔（1800-2500m）受到中度干扰的次生灌丛、针阔混交林和亚高山针叶林，通过对群落相似性指数的计测可以看出生境类型与物种分布具有连续性。     

中国小冰期区域气候演化研究

在我国不同地区通过不同代用资料如冰芯、树轮、孢粉、湖泊沉积物、历史文献记录等恢复的小冰期气候的基础上, 分析总结了小冰期我国气候演化的区域分异特征,并探讨其原因机制,力图为未来气候变化提供参考。     

小麦近缘种及小麦-簇毛麦染色体代换系、易位系的SSR分析

用20对小麦微卫星引物，对小麦近缘种和小麦-簇毛麦染色体代换系、易位系的基因组DNA进行PCR扩增，14对引物有扩增产物，其中10对引物可以在小麦近缘种间扩增出多态性标记．共扩增出分子量小于500的条带477条，其中342条具有多态性，每个SSR座位的等位基因数目在2～6个之间，平均为3．7个．11个实验材料的基因多态性(PIC)范围在0．4013～0．7281之间，平均为0．5725．根据NeiM的方法进行遗传距离分析，构建系统树，确立小麦及近缘种的亲缘关系，为麦类作物遗传资源的研究及在育种中的应用提供一些理论依据．