Modulated Fourier Expansions of Highly Oscillatory Differential Equations

Modulated Fourier expansions are developed as a tool for gaining insight into the long-time behavior of Hamiltonian systems with highly oscillatory solutions. Particle systems of Fermi–Pasta–Ulam type with light and heavy masses are considered as an example. It is shown that the harmonic energy of the highly oscillatory part is nearly conserved over times that are exponentially long in the high frequency. Unlike previous approaches to such problems, the technique used here does not employ nonlinear coordinate transforms and can therefore be extended to the analysis of numerical discretizations.     

A new hybrid stress element method for the analysis of elastoplastic solids

Based on a modified Hellinger/Reissner variational principle which includes the equivalent stress, equivalent plastic strain and non-conforming displacement increments as independent variables, a quadrilateral isoparametric hybrid stress element for the analysis of elastoplastic problem is proposed. By this formulation, the yield criterion and flow rule are satisfied in an average sense and greater accuracy can be obtained by using non-conforming displacement. A numerical example is presented to show that the present model has high accuracy and computational effectiveness.This project is supported by the Natural Science Foundation of the State Education Commission.     

钱塘江河口滩涂围垦区农田小兽种群分布格局初步研究

1987年8月和1989年8月对钱塘江河口滩涂围垦区农田小型兽类的凋查得知，农田小兽各种群的分布格局均为负二项分布.种群集聚度的大小依次为黄毛鼠.黑线姬鼠.臭的和大路助.在s种不同的农田类型中，各种群的集聚度有异，呈现不同的分布格局种群的集聚度与种群的密度、栖息地生境及群落结构之间都存在相互的影响.     

不同培养条件对基因工程疫苗菌抗原蛋白表达的影响

基因工程菌的表达条件研究在现代生物高技术产业化的发展中具有重要的意义。影响基因工程菌表达的因素主要有pH值、温度、诱导剂IPTG的浓度、诱导时间等。笔者分别就以上因素对基因工程菌抗原蛋白表达的影响进行了初步研究。在摇床培养条件下，外源基因表达蛋白的最适表达条件为终浓度O．8mmol/L的IPTG，32℃，诱导6h。     

Size Measurement of Very Small Spherical Particles by Mie Scattering Imaging (MSI)

The Mie Scattering Imaging method (MSI) gathers out‐of‐focus images of dispersed spherical particles present in a laser light sheet and extracts the individual particle diameter from these images. The general idea of the method has been around for more than a decade and a number of papers has dealt with it over recent years. Our work focuses on small particle sizes from 20 μm down to 2 μm, a range which has not been tackled so far although it is of great importance in particle systems. We present an optical set‐up with a special arrangement of camera lenses that allows to work in this range. An evaluation algorithm based on correlation of the experimental optical information with theoretical Mie scattering was found to give the most accurate results for particle sizing. Besides accuracy measurements on solid spheres the versatility of the method is demonstrated by an example of transient droplet growth between 2–7 μm.     

Improvement of lysine production by analog-sensitive and auxotroph mutants of the acetylene-utilizing bacterium gordona bronchialis (Rhodococcus bronchialis)

An acetylene utilizingGordona (Rhodococcus) bronchialis strain, screened for the production of fine chemicals, was found to be capable of producing small amounts of lysine. Attempts to produce amino-acid analogresistant and/or sensitive mutants and auxotrophs of this strain with increased lysine production were made following UV-irradiation orN-methyl-N’-nitro-N-nitrosoguanidine (MNNG) treatment. The bacterium exhibited surprisingly high resistance levels to the aforementioned mutagens which is attributed to highly effective inborn-repair systems. Natural resistance to high levels ofS-(2-aminoethyl)-l-cysteine (AEC) (2%) was observed, in contrast withd, l-aspartic acid hydroxamate (AAH),l-lysine hydroxamate (LHX) and β-fluoropyruvate (FP). A variety of amino-acid analog-resistant (AAH^r, LHX^r) or analog-sensitive (FP^s) mutants were produced following UV-irradiation or MNNG treatment. Similarly, a large number of auxotrophs (68) of different types were also obtained. From these, one FP^s mono-auxotroph and two poly-auxotrophs (with at least one requirement for the aspartic acid family) showed an increased lysine production (~1.8 g/L) comparable (4 g/L) to that found in other bacteria capable of utilizing long-chain hydrocarbons(1).     

循环载荷下缺口板弹塑性应变分布测定

用电测法测定了带有中心圆孔矩形铝合金（ＬＹ－１２－ＣＺ）板在循环载荷作用下横截面的弹塑性应变分布，同时测定了循环载荷下孔边应力──应变回线，弹塑性应变集中系数Ｋε和应力集中系数Ｋσ，并和四种近似公式的计算结果进行了比较。发现在循环加载情况下用电测法绘制载荷──应变回线，并根据回线出现畸变的现象，可以灵敏的检测裂纹的萌生和早期扩展。     

球面反射镜的放大自发辐射方法测量小信号增益的理论研究

提出了球面反射镜的放大自发辐射（ＡＳＥ）方法测量小信号增益的理论模型，给出了相应的小信号增益系数的计算公式，该公式具有精确，简洁，显函数等特点，该模型有抑制光束横向分布引起的测量误差的机制。     

加强螺旋胶管弯曲问题的研究

曲挠性能是橡胶软管的重要质量指标之一。本文从理论方面对多层钢丝缠绕螺旋胶管的弯曲问题进行了研究，建立了管轴曲率半径与材料性质及截面几何形状间的关系。根据材料的极限变形，导出管轴临界弯曲半径的计算方法。此法对橡胶制品的设计与制造具有一定的实用价值。     

As2O3联合小剂量化疗治疗急性早幼粒细胞白血病的临床研究

探讨治疗急性早幼粒细胞白血病（APL）更有效的方法，以延长患者的生存期，提高生活质量。采用As2O3注射液10mg/d加入10％葡萄注射液250－500mL静脉滴注，连续28d一个疗程；同时用可糖胞苷50－100mg或高三尖杉酯碱1－2mg加入10％葡萄糖注射250mL静脉滴注，7－10d为1疗程，观察其临床症状、血象及骨髓象的变化，并追踪观察其缓解率及生存期。结果表明，采用A2sO3注射液加小剂量化疗的方法治疗APL，有明显的疗效，能够有效控制APL病情，提高完全缓解率，减少白血病的复发率与患者死亡率。