Size Measurement of Very Small Spherical Particles by Mie Scattering Imaging (MSI)

The Mie Scattering Imaging method (MSI) gathers out‐of‐focus images of dispersed spherical particles present in a laser light sheet and extracts the individual particle diameter from these images. The general idea of the method has been around for more than a decade and a number of papers has dealt with it over recent years. Our work focuses on small particle sizes from 20 μm down to 2 μm, a range which has not been tackled so far although it is of great importance in particle systems. We present an optical set‐up with a special arrangement of camera lenses that allows to work in this range. An evaluation algorithm based on correlation of the experimental optical information with theoretical Mie scattering was found to give the most accurate results for particle sizing. Besides accuracy measurements on solid spheres the versatility of the method is demonstrated by an example of transient droplet growth between 2–7 μm.     

Improvement of lysine production by analog-sensitive and auxotroph mutants of the acetylene-utilizing bacterium gordona bronchialis (Rhodococcus bronchialis)

An acetylene utilizingGordona (Rhodococcus) bronchialis strain, screened for the production of fine chemicals, was found to be capable of producing small amounts of lysine. Attempts to produce amino-acid analogresistant and/or sensitive mutants and auxotrophs of this strain with increased lysine production were made following UV-irradiation orN-methyl-N’-nitro-N-nitrosoguanidine (MNNG) treatment. The bacterium exhibited surprisingly high resistance levels to the aforementioned mutagens which is attributed to highly effective inborn-repair systems. Natural resistance to high levels ofS-(2-aminoethyl)-l-cysteine (AEC) (2%) was observed, in contrast withd, l-aspartic acid hydroxamate (AAH),l-lysine hydroxamate (LHX) and β-fluoropyruvate (FP). A variety of amino-acid analog-resistant (AAH^r, LHX^r) or analog-sensitive (FP^s) mutants were produced following UV-irradiation or MNNG treatment. Similarly, a large number of auxotrophs (68) of different types were also obtained. From these, one FP^s mono-auxotroph and two poly-auxotrophs (with at least one requirement for the aspartic acid family) showed an increased lysine production (~1.8 g/L) comparable (4 g/L) to that found in other bacteria capable of utilizing long-chain hydrocarbons(1).     

循环载荷下缺口板弹塑性应变分布测定

用电测法测定了带有中心圆孔矩形铝合金（ＬＹ－１２－ＣＺ）板在循环载荷作用下横截面的弹塑性应变分布，同时测定了循环载荷下孔边应力──应变回线，弹塑性应变集中系数Ｋε和应力集中系数Ｋσ，并和四种近似公式的计算结果进行了比较。发现在循环加载情况下用电测法绘制载荷──应变回线，并根据回线出现畸变的现象，可以灵敏的检测裂纹的萌生和早期扩展。     

球面反射镜的放大自发辐射方法测量小信号增益的理论研究

提出了球面反射镜的放大自发辐射（ＡＳＥ）方法测量小信号增益的理论模型，给出了相应的小信号增益系数的计算公式，该公式具有精确，简洁，显函数等特点，该模型有抑制光束横向分布引起的测量误差的机制。     

加强螺旋胶管弯曲问题的研究

曲挠性能是橡胶软管的重要质量指标之一。本文从理论方面对多层钢丝缠绕螺旋胶管的弯曲问题进行了研究，建立了管轴曲率半径与材料性质及截面几何形状间的关系。根据材料的极限变形，导出管轴临界弯曲半径的计算方法。此法对橡胶制品的设计与制造具有一定的实用价值。     

As2O3联合小剂量化疗治疗急性早幼粒细胞白血病的临床研究

探讨治疗急性早幼粒细胞白血病（APL）更有效的方法，以延长患者的生存期，提高生活质量。采用As2O3注射液10mg/d加入10％葡萄注射液250－500mL静脉滴注，连续28d一个疗程；同时用可糖胞苷50－100mg或高三尖杉酯碱1－2mg加入10％葡萄糖注射250mL静脉滴注，7－10d为1疗程，观察其临床症状、血象及骨髓象的变化，并追踪观察其缓解率及生存期。结果表明，采用A2sO3注射液加小剂量化疗的方法治疗APL，有明显的疗效，能够有效控制APL病情，提高完全缓解率，减少白血病的复发率与患者死亡率。     

非线性计算固体力学的若干问题

基于作者近年来在非线性计算固体力学中的工作，讨论了在这个领域中非线性有限元、本构行为数值模拟、应变局部化等若干问题的研究现状和最近发展。希望本文有助于计算力学工作者了解非线性计算固体力学一些重要方面的当前发展动态与趋势，并推动它在工程领域中的应用。     

L—山梨糖发酵中的芽孢杆菌噬菌体及抗噬菌体菌株的选育

从济南制药厂L—山梨糖混合发酵液中分离得到四株芽孢杆菌噬菌体,其中一株来自寄主巨大芽孢杆菌,三株来自腊状芽孢杆菌,这些噬菌体都是有尾的,根据形态可分为二类。通过选育获得了几株抗噬菌体菌株,经摇瓶混合发酵试验,表明抗株不但具有稳定的抗性而且保持了原种的性能。     

Thickening process of polyethylene single crystals at an early stage of annealing

By the use of a position sensitive proportional counter, changes in small and wide angle X-ray scattering during annealing of polyethylene single crystal mats were measured from the start in successive spans of very short measuring time. At high temperatures, the long period relating to stacking of lamellae rapidly increased at an early stage, passed through a plateau, and thereafter again increased gradually. With a decrease in annealing temperature, the amount of its first rapid increase was reduced and the plateau changed into an ascending slope. At much lower annealing temperatures, the long period increased following the logt law after an induction time. The integral breadth of a peak corresponding to the long period first increased rapidly, simultaneously with the rapid increase in the long period, and thereafter decreased. Wide angle X-ray measurement showed that the integrated intensity of 110 reflection first decreased and then increased during annealing at high temperatures. This fall and rise process was more marked, when the annealing temperature is higher and the initial thickness of lamellae is smaller. From these observations, it was inferred that in the thickening process, stacking order of lamellae at first decreased because of rapid reorganization due to partial melting or melt-recrystallization and subsequently increased through increasing evenness of lamellar thickness.