经济法的理性思考——刍议经济法的调整对象

对以往的经济法的调整对象进行了评述,然后从经济关系演进的角度提出了自己的观点,即经济法的调整对象是人们在社会化大生产中的增量利益关系,进而试图从微观和宏观层面上具体阐述并构建经济法的调整对象。     

哌嗪嘧啶类CCR4拮抗剂的设计、合成及生物活性

基于对已报道的CCR4拮抗剂的构效关系分析, 设计并合成了一系列哌嗪嘧啶类化合物. 采用细胞趋化抑制实验测试了合成化合物的体外活性, 其中化合物8a的活性优于目前报道的活性最好的化合物BMS-397; 在小鼠鼻炎模型中, 化合物8a以极低的剂量达到了布地奈德(鼻炎临床治疗药物)的治疗效果. 采用毛细管电泳法测得化合物8a与CCR4 N端40肽的结合常数为(3.6179±0.5976)×10⁴ L/mol.     

Polybrominated Diphenyl Ethers and Heavy Metals in a Regulated E-Waste Recycling Site,Eastern China: Implications for Risk Management

Serious pollution of multiple chemicals in irregulated e-waste recycling sites (IR-sites) were extensively investigated. However, little is known about the pollution in regulated sites. This study investigated the occurrence of 21 polybrominated diphenyl ethers (PBDEs) and 10 metals in a regulated site, in Eastern China. The concentrations of PBDEs and Cd, Cu, Pb, Sb, and Zn in soils and sediments were 1–4 and 1–3 orders of magnitude lower than those reported in the IR-sites, respectively. However, these were generally comparable to those in the urban and industrial areas. In general, a moderate pollution of PBDEs and metals was present in the vegetables in this area. A health risk assessment model was used to calculate human exposure to metals in soils. The summed non-carcinogenic risks of metals and PBDEs in the investigated soils were 1.59–3.27 and 0.25–0.51 for children and adults, respectively. Arsenic contributed to 47% of the total risks and As risks in 71.4% of the total soil samples exceeded the acceptable level. These results suggested that the pollution from e-waste recycling could be substantially decreased by the regulated activities, relative to poorly controlled operations, but arsenic pollution from the regulated cycling should be further controlled.     

Maximal Effective Bandwidth of Constrained Traffic

We investigate the worst possible behavior of a stationary traffic source when the traffic emanating from it is required to meet certain constraints. Specifically, the peak rate of the source is required not to exceed a level and realizations must obey a leaky bucket constraint with bucket size and leak rate . The worst case source is considered to be the one with the largest effective bandwidth, a concept which arises in the large deviation theory of queueing networks and governs the asymptotic loss rate when a large number of sources send traffic to a single server queue. We conjecture the form of the worst case traffic in general and prove the conjecture for the special case when T, the time-scale parameter of the effective bandwidth, is less than both /(–) and /, the times taken respectively to fill and empty the leaky bucket.