电工电子实验室一体化建设探索

通过对实验室的重新规划、实验教材的建设、强化实验室的管理,进行电工电子实验的改革和探索。结合我校的实际情况,更新教育观念,整合电工电子实验室,利用计算机和网络技术,进行电子系统仿真和设计,实现教学和实验手段现代化,实行“开放型”实验模式,让师生有效利用资源,适应科技进步的要求,达到更好的教学效果。     

The Deuterated “Magic Methyl” Group: A Guide to Site-Selective Trideuteromethyl Incorporation and Labeling by Using CD3 Reagents

In the field of medicinal chemistry, the precise installation of a trideuteromethyl group is gaining ever-increasing attention. Site-selective incorporation of the deuterated “magic methyl” group can provide profound pharmacological benefits and can be considered an important tool for drug optimization and development. This review provides a structured overview, according to trideuteromethylation reagent, of currently established methods for site-selective trideuteromethylation of carbon atoms. In addition to CD₃, the selective introduction of CD₂H and CDH₂ groups is also considered. For all methods, the corresponding mechanism and scope are discussed whenever reported. As such, this review can be a starting point for synthetic chemists to further advance trideuteromethylation methodologies. At the same time, this review aims to be a guide for medicinal chemists, offering them the available C−CD₃ formation strategies for the preparation of new or modified drugs.     

Construction of mixed carboxylate and pyrogallate building units for luminescent metal-organic frameworks

A metal-organic framework,Ce-FDM-50,was constructed by employing gallic acid featuring both carboxylate and pyrogallate as the coordinating sites and Ce(Ⅲ).The co-assembly of the carboxylates and pyrogallates with two metal ions have achieved a new type of paddle wheel secondary building unit.These building units were further joined by organic struts to obtain frameworks in sql topology.This synthetic approach could be expanded to five different lanthanide metals(Nd,Eu,Gd,Tb,Yb)for the construction of a series of isoreticular MOFs based on FDM-50,and even MTV-MOFs in which mixed lanthanide metals with specific ratios were distributed.In addition,featuring the lanthanide metals as the inorganic nodes in the network,Tb-FDM-50 showed distinct luminescence properties that could be furtherly tuned for variable applications.     

Base Metal Catalyzed Isocyanide Insertions

Isocyanides are diverse C₁ building blocks considering their potential to react with nucleophiles, electrophiles, and radicals. Therefore, perhaps not surprisingly, isocyanides are highly valuable as inputs for multicomponent reactions (MCRs) and other one‐pot cascade processes. In the field of organometallic chemistry, isocyanides typically serve as ligands for transition metals. The coordination of isocyanides to metal centers alters the electronic distribution of the isocyano moiety, and reaction pathways can therefore be accessed that are not possible in the absence of the metal. The tunable reactivity of the isocyanide functional group by transition metals has evolved into numerous useful applications. Especially palladium‐catalyzed isocyanide insertion processes have emerged as powerful reactions in the past decade. However, reports on the use of earth‐abundant and cheap base metals in these types of transformations are scarce and have received far less attention. In this Minireview, we focus on these emerging base metal catalyzed reactions and highlight their potential in synthetic organic chemistry. Although mechanistic studies are still scarce, we discuss distinct proposed catalytic cycles and categorize the literature according to 1) the (hetero)atom bound to and 2) the type of bonding with the transition metal in which the (formal) insertion occurs.     

Acyl Fluorides in Late‐Transition‐Metal Catalysis

In this Review, we summarize the current state of the art in late‐transition‐metal‐catalyzed reactions of acyl fluorides, covering both their synthesis and further transformations. In organic reactions, the relationship between stability and reactivity of the starting substrates is usually characterized by a trade‐off. Yet, acyl fluorides display a very good balance between these properties, which is mostly due to their moderate electrophilicity. Thus, acyl fluorides (RCOF) can be used as versatile building blocks in transition‐metal‐catalyzed reactions, for example, as an “RCO” source in acyl coupling reactions, as an “R” source in decarbonylative coupling reactions, and as an “F” source in fluorination reactions. Starting from the cleavage of the acyl C?F bond in acyl fluorides, various transformations are accessible, including C?C, C?H, C?B, and C?F bond‐forming reactions that are catalyzed by transition‐metal catalysts that contain the Group 9–11 metals Co, Rh, Ir, Ni, Pd, or Cu.     

基于浙江省台风灾害保险数据的农村住房易损性评价

利用浙江省农业政策性保险试点项目中的农村住房保险及理赔数据,定量分析了浙江省2007年圣帕、韦帕及罗莎3场台风灾害期间农村住房投保金额、赔付金额、保额损失率的分县汇总数据,以及与这3场台风的极大风速、过程降水量等致灾因子强度的定量关系.研究发现,浙江省农村住房的台风灾害保险金额损失率,其对数与过程降雨量有着很好的线性相关关系.依据这一关系,建立了浙江省农村住房台风易损性方程并给出相关参数.     

点支式玻璃建筑中铸铝支承件承载性能

为了研究点支式玻璃建筑中铸铝支承件的承载性能,对3种典型铸铝支承件进行了足尺模型试验研究。按照实际工程中支承件的形式与尺寸制造模具,采用ZL105-T1和ZL111-T6这种铝合金材料铸造成足尺模型试件,借助万能试验机对试件进行加载试验,得出了试件的屈服荷载与极限荷载。根据试件的实际几何尺寸与材料属性,建立有限元模型对试验过程进行数值模拟。有限元分析结果与试验数据吻合良好,验证了有限元模型的可靠性。试验研究与有限元分析表明铸铝支承件的承载力较高,可以在实际工程中应用。     

罕遇地震下上海中心超高层的性能化抗震设计

参照CECS160(《建筑工程抗震性态设计通则》)和ASCE41(《American Society of Civil Engineers/SEI 41—06》),研究确定拟建的上海中心超高层建筑结构的性能化抗震设计目标,提出了直接用于该结构的基于材料本构关系的性能化抗震设计方法,以及基于位移的性能化抗震设计控制指标,选取合适的结构单元模型与合适的非线性动力分析技术相结合的方法,对上海中心超高层结构进行整体抗震性能评估.为该结构设计提供了有益的建议,并为基于位移的性能化抗震设计方法积累了资料.     

基于模糊层次分析法的既有住宅性能综合评价

以综合改建为目的,将既有住宅性能分为安全性、完好性、适用性、节能性、环境性和协调性等6类指标.运用模糊数学方法对层次分析法进行改进,确定各指标的权重,构建既有住宅性能综合评价模型.克服了传统评价方法的主观随意性,全面考虑各类指标的相互影响关系,改善评判过程中的不确定性.通过评价30个不同的案例,验证该评价模型具有综合性、客观性和可操作性的优点.通过案例讨论,提出各类住宅性能改建的实施方法.     

建筑结构风致内压的研究进展

从理论分析方面概括了内压控制方程的发展过程,评述了结构柔度、Helmholtz共振、干扰效应及结构内部分区等几个影响风致内压的主要因素,并从风洞试验、现场实测与CFD(计算流体动力学)模拟3个方面回顾与总结了国内外风致内压的研究进展,列举了各国风荷载规范对内压的描述.通过分析内压控制方程、影响因素以及研究方法中所存在的...