Liposomal structure: A comparative study on light scattering and chromatography techniques

Liposomes play an important role in medical and pharmaceutical science as, nanoscale drug carriers. One of the most important features is their size and size distribution, influencing both their bio-distribution and their targeting efficiency to tumors and also therapeutic activity of liposomal antitumor drugs. In this study, the effect of preparation method and molecular interaction on size and shape of liposome was studied. The size and shape characterization of liposomes was performed by asymmetrical flow field-flow fractionation coupled online with multi-angle light scattering (AF4-MALS). The size distributions obtained by AF4-MALS were compared to mean particle sizes and size distribution measured with other standard method such as Photon Correlation Spectroscopy (PCS). Furthermore, the effect of molecular interaction (hydrophilic and hydrophobic model drugs) on liposomal structure was assessed.     

基于 RIE 的自适应窄带干扰抑制算法

针对直接序列扩频(direct sequence spread spectrum,DSSS)通信系统中窄带干扰(narrow-band interference,NBI)抑制问题,将窄带干扰存在性识别技术(recognition of interference existence,RIE)和变换域窄带干扰抑制算法相结合,提出了一种自适应窄带干扰抑制算法.该算法能根据接收到的信号,利用基于能限因子的RIE算法判断接收信号中是否含有窄带干扰信号,从而决定是否需要对其进行干扰抑制处理.理论分析表明,当接收信号中不合窄带干扰或干扰信号较小时,既可减少由于窄带干扰抑制算法对有用信号造成的损伤,提高误码率性能,又能降低系统处理的复杂度.仿真结果表明,自适应窄带干扰抑制方案抑制干扰误码率性能明显优于非自适应窄带干扰抑制方案.     

与分担值相关的亚纯函数的正规性

设F为区域D上的亚纯函数族,a,b、c为相互判别的有穷复数,d为任意有穷复数,k为不等于2的正整数,若对任意f∈F,满足f-d的零点重数至少为k,并且Ef（k）（a）С Ef（a）,Ef（b）СEf（b）及Ef（c）СEf（k）（c）,则F在区域D上正规,并举例说明了定理中对厂零点重数的限制,及a、b、c相互判别的限制是必要的．     

论构建和谐社会的道德价值观

伴随着中国社会的发展,人们的道德价值观也发生着深刻的变化。当代流行的道德价值观虽然提供了社会主义和谐社会的思想基础,同时也出现了影响社会和谐的音符。根据实现人自身和谐、人际关系和谐、人与社会关系和谐、人与自然关系和谐的要求,构建与强化和谐社会的道德价值观显得尤为重要。     

焦耳热和电极反应对混凝土电通量试验的影响

研究了电通量试验过程中通过被测混凝土试件的电流（,）随测试时间（t）的变化规律及其影响因素。结果表明：当混凝土抗渗性较好时I-t关系曲线起伏变化很小,基本上呈一条直线,而当混凝土抗渗性较差时,由于焦耳热效应和电极反应影响较大,导致在整个测试过程中I-t关系曲线起伏变化剧烈并最终影响混凝土电通量测试结果的准确性。根据I-t关系给出了试验测试过程中是否需要冷水浴的条件;建议采用试验开始时刻通过被测混凝土试件的初始电流值I0来计算混凝土的6h电通量,并给出了计算公式。     

Direct Shooting Method for the Numerical Solution of Higher-Index DAE Optimal Control Problems

A method for the numerical solution of state-constrained optimal control problems subject to higher-index differential-algebraic equation (DAE) systems is introduced. For a broad and important class of DAE systems (semiexplicit systems with algebraic variables of different index), a direct multiple shooting method is developed. The multiple shooting method is based on the discretization of the optimal control problem and its transformation into a finite-dimensional nonlinear programming problem (NLP). Special attention is turned to the mandatory calculation of consistent initial values at the multiple shooting nodes within the iterative solution process of (NLP). Two different methods are proposed. The projection method guarantees consistency within each iteration, whereas the relaxation method achieves consistency only at an optimal solution. An illustrative example completes this article.     

Local Energy Statistics in Spin Glasses

Recently, Bauke and Mertens conjectured that the local statistics of energies in random spin systems with discrete spin space should in most circumstances be the same as in the random energy model. We review some rigorous results confirming the validity of this conjecture. In the context of the SK models, we analyse the limits of the validity of the conjecture for energy levels growing with the volume of the system. In the case of the Generalised Random energy model, we give a complete analysis for the behaviour of the local energy statistics at all energy scales. In particular, we show that, in this case, the REM conjecture holds exactly up to energies E _N < β _c N, where β _c is the critical temperature. We also explain the more complex behaviour that sets in at higher energies. Research supported in part by the DFG in the Dutch-German Bilateral Research Group “Mathematics of Random Spatial Models from Physics and Biology” and by the European Science Foundation in the Programme RDSES.     

高校自然科学学报学术评价研究

文章以统计资料为基础,对科技期刊及其自然科学学报学术评价的科学性和客观性进行了分析讨论,认为对期刊学术质量的认定,尤其是对高校自然科学学报来说,一定要实事求是科学客观地看待,不能绝对化,只有这样才能作出正确的学术定位,从而促进期刊健康地发展。     

意义世界的勘明

中国在晚近100多年的时间里,围绕着人与自然、个人与群体、道义与功利这三个基本的价值领域,经历了前现代价值系统的变革和现代价值观建构的曲折过程。今人返观此前150年价值观的变革史,可以清晰地勾勒出它渐次演进的轨迹。现代性的意义世界正在勘明。     

浅谈市场经济对大学生价值观的影响

市场经济的发展导致传统的价值观念受挫,这在很大程度上影响到大学生的价值观念。为保证大学生的健康发展,寻求对策,显得尤为重要。